Tag: M.W=200-250

Pant, Amar D.; Ruhela, R.; Limje, C.; Anil Kumar, S.; Singh, A. K.; Kumar, Suja A.; Sugandhi, S.; Kain, V.; Tomar, B. S. published the artcile< Evaluation of BenzoDODA grafted polymeric resin for rapid and reliable assaying of plutonium in sediment samples>, Category: amides-buliding-blocks, the main research area is plutonium BenzoDODA grafted polymeric resin sediment pollution; Alpha spectrometry; BenzoDODA grafted resin; Extraction chromatography; Plutonium; SPEC; Sediments.

The paper reports a new rapid radioanal. procedure for the determination of plutonium (Pu) in sediments by solid phase extraction chromatog. (SPEC) using Bis-(2-ethylhexyl) carbamoyl methoxy phenoxy-bis-(2-ethylhexyl) grafted resin, abbreviated as Benzodioxodiamide (BenzoDODA) grafted resin. The resin was synthesized and evaluated for its sorption behavior towards Pu in batch and column mode to determine its efficacy for selective recovery of Pu from sediment samples. The anal. procedure was based on the radiochem. separation of samples by acid digestion, followed by preconcentration of actinides by co-precipitation with Fe(OH)3 and finally selective recovery of Pu by SPEC using a column filled with BenzoDODA grafted resin. Pu was then radiometrically assayed by preparing alpha disk sources with electro-deposition followed by alpha spectrometry. The method was further validated with IAEA reference materials. This method gives reliable and reproducible results for the activity concentration of Pu in sediment samples within 24 h.

Journal of Environmental Radioactivity published new progress about Acid digestion. 5326-82-9 belongs to class amides-buliding-blocks, and the molecular formula is C10H20ClNO, Category: amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Bochenska, Maria; Banach, Robert; Zielinska, Anna; Kravtsov, Victor Ch. published the artcile< Lower rim substituted tert-butylcalix[4]arenes (I). The structure and complexing properties in ion-selective PVC membrane electrodes>, Computed Properties of 5326-82-9, the main research area is calixarene lower rim amide substituted preparation; ion selective PVC membrane electrode calixarenamide.

Di- and tetraamide tert-butylcalix[4]arenes were synthesized and described. Their ionophoric properties were studied in liquid membrane ion-selective electrodes. The correlation between the chem. structure (conformation in solution determined by 1H NMR) and potentiometric ion-selectivity and complex formation constant have been studied. The PVC membrane electrodes based on tetraamides I (R = n-Bu2N, morpholino, 1-piperidinyl, CH3(CH2)6MeN) show high sodium selectivity and are stable and long lasting. Disubstituted amides II (R = Et2N, n-Pr2N, i-Pr2N, n-Bu2N, i-Bu2N, morpholino, 1-piperidinyl) are selective for larger and more lipophilic ions, e.g., guanidinium ion. The crystal structure of the diamide II (R = n-Bu2N) was determined by single crystal X-ray anal. Crystals of II (R = n-Bu2N) are triclinic, space group P-1, with: a = 16,669(8), b = 17.795(10), c = 20.984(8) Å, α = 91.08(4)°, γ = 90.73(4)° and Z = 4. Ionophore II (R = n-Bu2N) possesses a distorted cone conformation and is substituted at the proximal phenol rings.

Journal of Inclusion Phenomena and Macrocyclic Chemistry published new progress about Conformation. 5326-82-9 belongs to class amides-buliding-blocks, and the molecular formula is C10H20ClNO, Computed Properties of 5326-82-9.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Kannan, Shanmugaperumal; Chetty, Kuna Venugopal; Venugopal, Venkatarama; Drew, Michael G. B. published the artcile< Extraction and coordination studies of the unexplored bifunctional ligand carbamoyl methyl sulfoxide (CMSO) with uranium(VI) and cerium(III) nitrates. Synthesis and structures of [UO2(NO3)2(PhSOCH2CONiBu2)] and [Ce(NO3)3(PhSOCH2CONBu2)2]>, Electric Literature of 5326-82-9, the main research area is carbamoylmethylsulfoxide preparation complexation cerium uranyl; cerium carbamoylmethylsulfoxide complex preparation; uranyl carbamoylmethylsulfoxide complex preparation; crystal structure cerium uranyl carbamoylmethylsulfoxide complex; extraction actinide carbamoylmethylsulfoxide.

The bifunctional carbamoyl Me sulfoxide ligands, PhCH2SOCH2CONHPh (L1), PhCH2SOCH2CONHCH2Ph (L2), PhSOCH2CONiPr2 (L3), PhSOCH2CONBu2 (L4), PhSOCH2CONiBu2 (L5) and PhSOCH2CON(C8H17)2 (L6) were synthesized and characterized by spectroscopic methods. The selected coordination chem. of L1, L3, L4 and L5 with [UO2(NO3)2] and [Ce(NO3)3] was evaluated. The structures of [UO2(NO3)2(PhSOCH2CONiBu2)] (10) and [Ce(NO3)3(PhSOCH2CONBu2)2] (12) were determined by single crystal x-ray diffraction methods. Preliminary extraction studies of ligand L6 with U(VI), Pu(IV) and Am(III) in tracer level showed an appreciable extraction for U(VI) and Pu(IV) in up to 10 M HNO3 but not for Am(III). Thermal studies on compounds [UO2(NO3)2( PhSOCH2CONiPr2)] (8) and 10 in air revealed that the ligands can be destroyed completely on incineration. The electron spray mass spectra of compounds 8 and 10 in acetone show that extensive ligand distribution reactions occur in solution to give a mixture of products with ligand to metal ratios of 1:1 and 2:1. However, 10 retains its solid state structure in CH2Cl2.

Dalton Transactions published new progress about Actinides Role: PEP (Physical, Engineering or Chemical Process), PROC (Process). 5326-82-9 belongs to class amides-buliding-blocks, and the molecular formula is C10H20ClNO, Electric Literature of 5326-82-9.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wang, Yu-Wei; Zheng, Lei; Jia, Feng-Cheng; Chen, Yun-Feng; Wu, An-Xin published the artcile< Oxidative ring-opening of isatins for the synthesis of 2-aminobenzamides and 2-aminobenzoates>, Recommanded Product: 2-Amino-4-bromobenzamide, the main research area is aminobenzamide aminobenzoate preparation; isatin alc ammonia tandem oxidative ring opening.

An efficient and practical isatin-based oxidative domino protocol has been developed for the facile synthesis of 2-aminobenzamides and 2-aminobenzoates. The robust nature of this reaction system is reflected by accessible starting materials, room temperature and high-yield gram-scale synthesis.

Tetrahedron published new progress about Aromatic esters Role: SPN (Synthetic Preparation), PREP (Preparation). 112253-70-0 belongs to class amides-buliding-blocks, and the molecular formula is C7H7BrN2O, Recommanded Product: 2-Amino-4-bromobenzamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Bhargava, P. N.; Prakash, Shree published the artcile< Synthesis of S-substituted-2-mercapto-3-aryl (or aralkyl)-4 (3H) quinazolinones: their CNS and antimicrobial activity>, Related Products of 5326-82-9, the main research area is quinazolinylthioacetamide; thioacetamide quinazolinyl; acetamide quinazolinylthio; central stimulant quinazolinylthioacetamide; bactericide quinazolinylthioacetamide; fungicide quinazolinylthioacetamide; quinazolinethiol chloroacetamide.

Quinazolinylthioacetamides I (R = Ph, 2-MeC6H4, 4-ClC6H4, 4-MeOC6H4, 4-EtOC6H4, R1 = CH2CHMe2, CH2Ph; R = 4-MeC6H4, R1 = CH2CHMe2; R = 3-MeC6H4, PhCH2, R1 = CH2Ph) were obtained by treating quinazolinethiols with ClCH2CONR12. I increased spontaneous motor activity in mice at 600 mg/kg but had no bactericidal or fungicidal activity.

Indian Journal of Pharmacy published new progress about Central nervous system stimulants. 5326-82-9 belongs to class amides-buliding-blocks, and the molecular formula is C10H20ClNO, Related Products of 5326-82-9.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zhang, Han; Liu, Huan; Luo, Xiao; Wang, Yuxi; Liu, Yuan; Jin, Hongwei; Liu, Zhenming; Yang, Wei; Yu, Peilin; Zhang, Liangren; Zhang, Lihe published the artcile< Design, synthesis and biological activities of 2,3-dihydroquinazolin-4(1H)-one derivatives as TRPM2 inhibitors>, COA of Formula: C7H7BrN2O, the main research area is dihydroquinazolinone preparation SAR human TRPM2 inhibitor; 2,3-Dihydroquinazolin-4(1H)-ones; Inhibitors; SAR; TRPM2; Virtual screening.

In this study, a series of novel 2,3-dihydroquinazolin-4(1H)-one derivatives, e.g. I was subsequently synthesized and characterized. Their inhibitory activity against the TRPM2 channel was evaluated by calcium imaging and electrophysiol. approaches. Some of the compounds exhibited significant inhibitory activity, especially 6-bromo-8-methyl-2-[3-(2-naphthyl)-1H-pyrazol-4-yl]-2,3-dihydro-1H-quinazolin-4-one which showed an IC50 of 3.7μM against TRPM2 and did not affect the TRPM8 channel. The summarized structure-activity relationship (SAR) provided valuable insights for further development of specific TRPM2 targeted inhibitors.

European Journal of Medicinal Chemistry published new progress about Homo sapiens. 112253-70-0 belongs to class amides-buliding-blocks, and the molecular formula is C7H7BrN2O, COA of Formula: C7H7BrN2O.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Guo, Zhijun; Zhang, Weiguang; Niu, Yanning; Tan, Minyu published the artcile< Solvent extraction and separation of thorium(IV) and uranium(VI) by an ether-amide type tripodand>, Synthetic Route of 5326-82-9, the main research area is solvent thorium uranium ether amide tripodand picrate fuel reprocessing.

1,1,1-Tris(N,N-diisobutylcarbamoyl-methylene-oxymethyl)propane (L) was prepared and characterized by using IR, 1H NMR and pos.-ion FAB mass spectra. The extraction of Th4+ and UO22+ with L was studied as a function of concentration of free extractant in an organic phase and of picrate in an aqueous phase from a picrate-nitrate medium at 293 ± 1 K, in view of nuclear fuel reprocessing. The extractability of L for Th4+ is larger than that for UO22+. Both extraction % of Th4+ and UO22+ decreased with an increase in the concentration of HNO3. The mechanism of extraction of Th4+ with L was proposed. The composition of extracted species of L with Th4+ in the organic phase is ThL(Pic)2(NO3)2. The results of extraction of trace 234Th4+ with L from the picrate-nitrate medium containing UO22- (the initial concentration of UO22+, CUO22+0 = 1.23 × 10-4 mol/dm3 (M)) agreed well with those from the extraction of single component solutions The tripodand is useful in separation of Th4+ and UO22+ from each other in picrate-nitrate media with a relatively high separation factor.

Radiochimica Acta published new progress about Nuclear fuel reprocessing. 5326-82-9 belongs to class amides-buliding-blocks, and the molecular formula is C10H20ClNO, Synthetic Route of 5326-82-9.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Gadzekpo, V. P. Y.; Hungerford, J. M.; Kadry, A. M.; Ibrahim, Y. A.; Xie, R. Y.; Christian, Gary D. published the artcile< Comparative study of neutral carriers in polymeric lithium ion selective electrodes>, Product Details of C10H20ClNO, the main research area is ionophore lithium selective electrode; lipophilic diamide ionophore lithium selective electrode; pyridine diamide ionophore lithium selective electrode; furan diamide ionophore lithium selective electrode; dioxanonane diamide ionophore lithium selective electrode; polyether diamide ionophore lithium selective electrode; ether diamide ionophore lithium selective electrode.

New lipophilic diamide compounds were synthesized and tested as ionophores for Li in poly(vinyl chloride) (PVC) membrane electrodes, including compounds with pyridine, furan, dioxanonane, and polyether backbones with different lipophilic diamide groups. The new ionophores were compared with previously reported ionophores under similar measurement conditions with the same plasticizer, tris(2-ethylhexyl) phosphate, in all membranes. Fixed interference and matched potential methods were used to determine relative selectivity coefficients for all the electrodes. The highest selectivity for Li relative to Na was obtained with N,N-dicyclohexyl-N’,N’-diisobutyl-cis-cyclohexane-1,2-dicarboxamide (140:1) and the 14-crown-4 ether, 3-dodecyl-3-methyl-1,5,8,12-tetraoxacyclotetradecane (125:1) when using NPOE (o-nitrophenyl octyl ether) plasticizer. The latter exhibited faster response at low Li concentrations It exhibited consistently high selectivity using different measurement methods and was stable for 5 mo.

Analytical Chemistry published new progress about Diamides. 5326-82-9 belongs to class amides-buliding-blocks, and the molecular formula is C10H20ClNO, Product Details of C10H20ClNO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Gatrone, Ralph C.; Kaplan, L.; Horwitz, E. Philip published the artcile< The synthesis and purification of the carbamoylmethylphosphine oxides>, COA of Formula: C10H20ClNO, the main research area is carbamoylmethylphosphine oxide preparation purification; phosphine oxide carbamoylmethyl.

The details of the synthesis and purification of sym. and unsym. carbamoylmethylphosphine oxides are described. The approaches used to provide a variety of substitution patterns around the two potential donor groups include the Arbusov, Michaelis-Becker, and Grignard reactions. Several methods for purifying the extractants were studied. The use of acidic and basic ion exchange resins in conjunction was developed for the removal of acidic impurities which are very troublesome to the extraction performances of these compounds

Solvent Extraction and Ion Exchange published new progress about Purification. 5326-82-9 belongs to class amides-buliding-blocks, and the molecular formula is C10H20ClNO, COA of Formula: C10H20ClNO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Cai, Yue-Ming; Zhang, Xin; An, Cui; Yang, Ye-Fei; Liu, Wei; Gao, Wen-Xia; Huang, Xiao-Bo; Zhou, Yun-Bing; Liu, Miao-Chang; Wu, Hua-Yue published the artcile< Catalyst-free oxidative N-N coupling for the synthesis of 1,2,3-triazole compounds with tBuONO>, Related Products of 112253-70-0, the main research area is benzotriazinone preparation; aminobenzamide coupling; benzothiadiazole preparation; aminothiol N S coupling; triazolopyridine preparation; pyridinyl methanamine coupling.

A catalyst-free method was developed to synthesize 1,2,3-benzotriazinones I [R = H, 6-Cl, 6-Br, etc.] and 1,2,3-benzothiadiazoles II [R1 = H, 6-Cl, 6-Br, etc.] from 2-amino-benzamides and 2-amino thiols. Of particular note was that the one-step synthesis route to access [1,2,3]triazolo[1,5-a]pyridines III [R2 = H, Ph, 4-ClC6H4; R3 = H, 7-Me, 7-Br] from pyridin-2-ylmethanamine was reported for the first time. This approach featured no use of catalyst, extremely mild conditions and excellent efficiency.

Organic Chemistry Frontiers published new progress about Amino thiols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112253-70-0 belongs to class amides-buliding-blocks, and the molecular formula is C7H7BrN2O, Related Products of 112253-70-0.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics