Tag: M.W=150-200

Titskii, G. D. published the artcileIsoparametric correlations in reactions of 4-R-N-arylpyridinium salts with arylamines, Recommanded Product: N,N-Diethylisonicotinamide, the publication is Theoretical and Experimental Chemistry (Translation of Teoreticheskaya i Eksperimental’naya Khimiya) (2000), 35(4), 215-220, database is CAplus.

Isoparametric dependencies of the structure of the reagents (including noncatalytic rate constants, substitution constants (σ⁰), basicity constants, and charges at the reaction centers) were obtained for the reactions between 4-R-N-(2,4-dinitrophenyl)pyridinium salts with arylamines. The electron-acceptor 4-R-substituents studied reduced the pos. charge on the reaction center (the α-atom) and the N atom of the N-arylpyridinium cation.

Theoretical and Experimental Chemistry (Translation of Teoreticheskaya i Eksperimental’naya Khimiya) published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C9H9F5Si, Recommanded Product: N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Joris, L. published the artcileEffects of polar aprotic solvents on linear free-energy relations in hydrogen-bonded complex formation, Application of N,N-Diethyl-2,2,2-trifluoroacetamide, the publication is Journal of the American Chemical Society (1972), 94(10), 3438-42, database is CAplus.

The effects of polar aprotic solvents on linear free-energy relations in H-bonded complex formation were studied. The behavior of strong pKa bases has suggested the utility of the concept of solvent-induced (partial) ionization in H-bonded complexes as distinct from partial H-bonded ion-pair formation or ionic dissociation

Journal of the American Chemical Society published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Application of N,N-Diethyl-2,2,2-trifluoroacetamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Schmidt, Joachim published the artcileBasic hydrolysis of N-alkyltrifluoroacetamides in 50% ethanol. Are these reactions suitable for determining steric substituent constants?, Category: amides-buliding-blocks, the publication is Wissenschaftliche Zeitschrift der Paedagogischen Hochschule Karl Liebknecht Potsdam (1987), 31(1), 23-31, database is CAplus.

The velocity constants for the second-order basic hydrolysis of CF₃CONRR¹ [R = Me, Et, Pr, Me₂CH, Bu, Me₂CHCH₂, Me(CH₂)_n (n = 4, 5, 6, 7), Me₂CHCH₂CH₂, Me₃C, R¹ = H (I); R = R¹ = H, Me, Et, Pr] in 50% aqueous EtOH, determined at ≤75% reaction, had good LFER with Charton υ(OR) or υ(NHR) steric constants The extensive deprotonation of I was kinetically characterized.

Wissenschaftliche Zeitschrift der Paedagogischen Hochschule Karl Liebknecht Potsdam published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Giurg, M. published the artcileHydrogen peroxide oxidation of N,N-dimethylhydrazones promoted by selenium compounds, titanosilicalites or acetonitrile, Application of 2,4-Dichlorobenzamide, the publication is Polish Journal of Chemistry (2002), 76(12), 1713-1720, database is CAplus.

Hydrogen peroxide oxidation of aldehyde dimethylhydrazones promoted by the title reagents has been investigated. Depending on the substrate, nitriles or amides were obatined as the major products accompanied by carboxylic acids and aldehydes. Formation of nitriles using H₂O₂ in acetonitrile without base is limited to electron-rich substrates. Reaction of electron-deficient dimethylhydrazones with hydrogen peroxide and aqueous sodium carbonate in acetonitrile/water gives amides as the major products. Aliphatic, unsaturated and aromatic nitriles are prepared by the oxidation of the corresponding aldehyde dimethylhydrazones with hydrogen peroxide in the presence of poly(bis-9,10-anthracenyl) diselenide (PADS) as a catalyst. A mechanism for the oxidation of N,N-dimethylhydrazones is proposed; peroxyiminoacetic acid is suggested as the active oxidant in situ.

Polish Journal of Chemistry published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Application of 2,4-Dichlorobenzamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Wang, Zi-Qiang published the artcileElectrochemical Synthesis of 3,5-Disubstituted-1,2,4-thiadiazoles through NH₄I-Mediated Dimerization of Thioamides, Product Details of C8H9NOS, the publication is Advanced Synthesis & Catalysis (2018), 360(21), 4043-4048, database is CAplus.

A electrochem. method for the synthesis of 3,5-disubstituted-1,2,4-thiadiazoles through NH₄I-mediated dimerization of thioamides is reported. Using the inexpensive NH₄I as electrolyte and catalyst, this electrosynthesis approach requires no oxidizing agents and enables the convenient production of diverse 1,2,4-thiadiazole products. The approach is an example of S-N bond construction through the electrochem. method.

Advanced Synthesis & Catalysis published new progress about 64559-06-4. 64559-06-4 belongs to amides-buliding-blocks, auxiliary class Amine,Benzene,Amide,Ether, name is 3-Methoxybenzothioamide, and the molecular formula is C16H14O6, Product Details of C8H9NOS.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Srinivasan, S. published the artcileFormamide as an ammonia synthon in amination of acid chlorides, Recommanded Product: 2,4-Dichlorobenzamide, the publication is Synthetic Communications (2010), 40(23), 3538-3543, database is CAplus.

The use of formamide as a convenient source of ammonia was explored for the direct transformation of acid chlorides to primary amides. Various aliphatic, alicyclic aromatic, and heterocyclic acid chlorides are converted to the corresponding carboxamides in good yields (75-94%).

Synthetic Communications published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C10H10O2, Recommanded Product: 2,4-Dichlorobenzamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Zali-Boeini, Hassan published the artcileTribromo Phloroglucinol as a Novel and Highly Efficient Reagent for the Conversion of Benzothioamides to the Corresponding 1,2,4-Thiadiazoles, Quality Control of 2447-79-2, the publication is Synthetic Communications (2015), 45(14), 1681-1687, database is CAplus.

2,4,6-Tribromo-1,3,5-trihydroxybenzene (TBTHB) as a reagent was efficiently reacted with 6 molar equivalents of benzothioamides in DMSO (DMSO), and the corresponding 3,5-diaryl-1,2,4-thiadiazoles were obtained in almost quant. yields (91-98%) and in short times (15-20 min) with the formation of hexahydroxybenzene as a rather valuable byproduct.

Synthetic Communications published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C12H13NO3, Quality Control of 2447-79-2.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Wang, Bin published the artcileNew and convergent synthesis of saflufenacil, Safety of N-Methyl-N-isopropylsulfamoyl amide, the publication is Journal of Heterocyclic Chemistry (2020), 57(1), 151-156, database is CAplus.

A new practical and hundred-gram scale synthesis of saflufenacil, a protoporphyrinogen oxidase (PPO) inhibitor herbicide was described. The key intermediate N-methyl-N-iso-Pr sulfamide was obtained from sulfuryl chloride isocyanate, t-butanol and N-methyl-N-isopropylamine in 74.8% yield over 3 steps. Saflufenacil was prepared in 48.6% yield over 8 steps and 98.7% purity (HPLC).

Journal of Heterocyclic Chemistry published new progress about 372136-76-0. 372136-76-0 belongs to amides-buliding-blocks, auxiliary class Sulfamide,Amine,Aliphatic hydrocarbon chain, name is N-Methyl-N-isopropylsulfamoyl amide, and the molecular formula is C4H6O3, Safety of N-Methyl-N-isopropylsulfamoyl amide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Gabryelski, Wlad. published the artcileAbsorption of ultra-violet light by some organic substances. XXVIII, Recommanded Product: N,N-Diethylisonicotinamide, the publication is Bulletin International de l’Academie Polonaise des Sciences et des Lettres, Classe des Sciences Mathematiques et Naturelles, Serie A: Sciences Mathematiques (1933), 87-94, database is CAplus.

cf. C. A. 24, 21. The following substances do not cause selective absorption of ultra-violet light between 4900 and 2100 A. U.: cellobiose (in H₂O), raffinose, acetylcellobiose, β-acetyllactobiose (in CHCl₃), acetylsucrose (in CHCl₃), acetylmaltose (in CHCl₃). The 2 absorption bands with maximum at 2680 and 3200 A. U., which appear when glucose is treated with NaOH in weak concentrations (C. A. 26, 5078) are probably due to the aldehyde form, for if the NaOH is neutralized with HCl after a short time, the original spectrum showing practically no selective absorption is obtained. Prolonged action of OH^– on glucose gives a product showing selective absorption which does not disappear on addition of acid.

Bulletin International de l’Academie Polonaise des Sciences et des Lettres, Classe des Sciences Mathematiques et Naturelles, Serie A: Sciences Mathematiques published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Recommanded Product: N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Mayhoub, Abdelrahman S. published the artcileOptimizing thiadiazole analogues of resveratrol versus three chemopreventive targets, Name: 2,4-Dichlorobenzamide, the publication is Bioorganic & Medicinal Chemistry (2012), 20(1), 510-520, database is CAplus and MEDLINE.

Chemoprevention is an approach to decrease cancer morbidity and mortality through inhibition of carcinogenesis and prevention of disease progression. Although the trans stilbene derivative resveratrol has chemopreventive properties, its action is compromised by weak non-specific effects on many biol. targets. Replacement of the stilbene ethylenic bridge of resveratrol with a 1,2,4-thiadiazole heterocycle and modification of the substituents on the two aromatic rings afforded potential chemopreventive agents with enhanced potencies and selectivities when evaluated as inhibitors of aromatase and NF-κB and inducers of quinone reductase 1 (QR1).

Bioorganic & Medicinal Chemistry published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Name: 2,4-Dichlorobenzamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics