Tag: M.W=150-200

Tang, SY; Liu, Y; Li, LJ; Ren, XH; Li, J; Yang, GY; Li, H; Yuan, BX in [Tang, Shanyu; Li, Longjia; Ren, Xuanhe; Li, Jiao; Yang, Guanyu; Li, Heng; Yuan, Bingxin] Zhengzhou Univ, Dept Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China; [Liu, Yan] Zhengzhou Univ, Sch Life Sci, Zhengzhou 450001, Henan, Peoples R China published Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S-H/N-H in 2019, Cited 44. Name: Diphenylmethanamine. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A practical and scalable electrochemical oxidation of S-H and N-H was developed. This oxidant-and catalyst-free electrochemical process enables S-N bond formation with inexpensive nickel electrodes in an undivided cell. This procedure exhibits broad substrate scopes and good functional-group compatibility. A 50 g scale oxidative coupling augurs well for industrial applications.

Name: Diphenylmethanamine. About Diphenylmethanamine, If you have any questions, you can contact Tang, SY; Liu, Y; Li, LJ; Ren, XH; Li, J; Yang, GY; Li, H; Yuan, BX or concate me.

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An article New approach for induction of alkyl moiety to aliphatic amines by NaBH(OAc)(3) with carboxylic acid WOS:000533533000015 published article about N-ALKYLATION in [Tamura, Satoru; Sugawara, Aoi; Sato, Erika; Sato, Fuka; Sato, Keigo; Kawano, Tomikazu] Iwate Med Univ, Sch Pharm, Dept Med & Organ Chem, Yahaba, Iwate 0283694, Japan in 2020.0, Cited 13.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Product Details of 91-00-9

We had found the novel N-alkylation method, which utilizes carboxylic acids as alkyl sources with sodium triacetoxyborohydride [NaBH(OAc)(3)]. Our methodology had been revealed to have some advantages over the reported similar procedures. Through the further investigation about our method, it was disclosed that acetonitrile was the suitable solvent and N-alkylation for aliphatic amines were also smoothly proceeded. On the way of the research, we discovered that 4-hydroxybutyl moiety was induced to aniline by use of old THF containing peroxidic materials. (C) 2020 Elsevier Ltd. All rights reserved.

About Diphenylmethanamine, If you have any questions, you can contact Tamura, S; Sugawara, A; Sato, E; Sato, F; Sato, K; Kawano, T or concate me.. Product Details of 91-00-9

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An article Highly Active Chiral Dilithium(I) Binaphthyldisulfonate Catalysts for Enantio- and Chemoselective Strecker-Type Reactions WOS:000485090400053 published article about TRIMETHYLSILYL CYANIDE; ENANTIOSELECTIVE CYANOSILYLATION; PRACTICAL SYNTHESIS; AMINO-ACIDS; CYANATION; IMINES; PENTACOORDINATE; HYDROCYANATION; REACTIVITY; ALDIMINES in [Hatano, Manabu; Nishio, Kosuke; Mochizuki, Takuya; Nishikawa, Keisuke; Ishihara, Kazuaki] Nagoya Univ, Grad Sch Engn, Chikusa Ku, Furo Cho, Nagoya, Aichi 4648603, Japan in 2019.0, Cited 84.0. Product Details of 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

An enantioselective Strecker-type reaction of aldimines and ketimines was developed by using a chiral dilithium(I) binaphthyldisulfonate as a chiral acid-base cooperative catalyst. The present catalytic system features an extremely short reaction time (10 min to 4 h), unlike conventional catalytic systems. Along with the design of stronger chiral Li(I) Lewis acid catalysts, a highly reactive pentacoordinate silicate generated in situ could promote the reactions. In particular, instead of unstable N-Bn Strecker products, more stable N-CH2 (9-anthryl) and N-CH2 (1-naphthyl) Strecker products could be obtained in high yields with high enantioselectivities. By a switch of the present and previous catalyst systems, chemoselective cyanation to a ketoaldimine could be performed, respectively. Moreover, mechanistic investigations provided useful information regarding the active catalysts, catalytic cycles, and possible transition states.

Product Details of 91-00-9. About Diphenylmethanamine, If you have any questions, you can contact Hatano, M; Nishio, K; Mochizuki, T; Nishikawa, K; Ishihara, K or concate me.

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Authors Chang, YJ; Cao, M; Chan, JZ; Zhao, CY; Wang, YK; Yang, R; Wasa, M in AMER CHEMICAL SOC published article about in [Chang, Yejin; Cao, Min; Chan, Jessica Z.; Zhao, Cunyuan; Wang, Yuankai; Yang, Rose; Wasa, Masayuki] Boston Coll, Merkert Chem Ctr, Dept Chem, Chestnut Hill, MA 02467 USA in 2021.0, Cited 123.0. SDS of cas: 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

We disclose a catalytic method for beta-C(sp(3))-H functionalization of N-alkylamines for the synthesis of enantiomerically enriched beta-substituted amines, entities prevalent in pharmaceutical compounds and used to generate different families of chiral catalysts. We demonstrate that a catalyst system comprising of seemingly competitive Lewis acids, B(C6F5)(3), and a chiral Mg- or Sc-based complex, promotes the highly enantioselective union of N-alkylamines and alpha,beta-unsaturated compounds. An array of delta-amino carbonyl compounds was synthesized under redox-neutral conditions by enantioselective reaction of a N-alkylamine-derived enamine and an electrophile activated by the chiral Lewis acid co-catalyst. The utility of the approach is highlighted by late-stage beta-C-H functionalization of bioactive amines. Investigations in regard to the mechanistic nuances of the catalytic processes are described.

About Diphenylmethanamine, If you have any questions, you can contact Chang, YJ; Cao, M; Chan, JZ; Zhao, CY; Wang, YK; Yang, R; Wasa, M or concate me.. SDS of cas: 91-00-9

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Recommanded Product: 91-00-9. Samuelsen, S; Santilli, C; Ahlquist, MSG; Madsen, R in [Samuelsen, SimoneV.; Santilli, Carola; Madsen, Robert] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark; [Ahlquist, Marten S. G.] KTH Royal Inst Technol, Dept Theoret Chem & Biol, Sch Engn Sci Chem Biotechnol & Hlth, S-10691 Stockholm, Sweden published Development and mechanistic investigation of the manganese(iii) salen-catalyzed dehydrogenation of alcohols in 2019.0, Cited 64.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

The first example of a manganese(III) catalyst for the acceptorless dehydrogenation of alcohols is presented. N,N’-Bis(salicylidene)-1,2-cyclohexanediaminomanganese(III) chloride (2) has been shown to catalyze the direct synthesis of imines from a variety of alcohols and amines with the liberation of hydrogen gas. The mechanism has been investigated experimentally with labelled substrates and theoretically with DFT calculations. The results indicate a metal-ligand bifunctional pathway in which both imine groups in the salen ligand are first reduced to form a manganese(III) amido complex as the catalytically active species. Dehydrogenation of the alcohol then takes place by a stepwise outer-sphere hydrogen transfer generating a manganese(III) salan hydride from which hydrogen gas is released.

Recommanded Product: 91-00-9. About Diphenylmethanamine, If you have any questions, you can contact Samuelsen, S; Santilli, C; Ahlquist, MSG; Madsen, R or concate me.

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I found the field of Chemistry very interesting. Saw the article Reductive Deamination with Hydrosilanes Catalyzed by B(C6F5)(3) published in 2020.0. Safety of Diphenylmethanamine, Reprint Addresses Oestreich, M (corresponding author), Tech Univ Berlin, Inst Chem, Str 17 Juni 115, D-10623 Berlin, Germany.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

The strong boron Lewis acid tris(pentafluorophenyl)borane B(C6F5)(3) is known to catalyze the dehydrogenative coupling of certain amines and hydrosilanes at elevated temperatures. At higher temperature, the dehydrogenation pathway competes with cleavage of the C-N bond and defunctionalization is obtained. This can be turned into a useful methodology for the transition-metal-free reductive deamination of a broad range of amines as well as heterocumulenes such as an isocyanate and an isothiocyanate.

Safety of Diphenylmethanamine. About Diphenylmethanamine, If you have any questions, you can contact Fang, HQ; Oestreich, M or concate me.

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Amide – Wikipedia,
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In 2020.0 EUR J MED CHEM published article about HUMAN BRAIN; ARECAIDINE; AGONIST; LOGP; OPPORTUNITIES; GUVACINE; SUBTYPES in [Ozenil, Marius; Pacher, Katharina; Balber, Theresa; Vraka, Chrysoula; Mitterhauser, Markus; Wadsak, Wolfgang; Hacker, Marcus; Pichler, Verena] Med Univ Vienna, Dept Biomed Imaging & Image Guided Therapy, Div Nucl Med, Vienna, Austria; [Balber, Theresa; Mitterhauser, Markus] Ludwig Boltzmann Inst Appl Diagnost, Vienna, Austria; [Roller, Alexander] Univ Vienna, Fac Chem, Xray Struct Anal Ctr, Vienna, Austria; [Holzer, Wolfgang; Spreitzer, Helmut] Univ Vienna, Fac Life Sci, Dept Pharmaceut Chem, Vienna, Austria; [Wadsak, Wolfgang] CBmed GmbH, Ctr Biomarker Res Med, Graz, Austria in 2020.0, Cited 50.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. COA of Formula: C13H13N

Supported by their involvement in many neurodegenerative disorders, muscarinic acetylcholine receptors ( mAChRs) are an interesting target for PET imaging. Nevertheless, no radiotracer is established in clinical routine. Within this work we aim to develop novel PET tracers based on the structure of arecoline. Fifteen novel arecoline derivatives were synthesized, characterized and tested for their affinity to the mAChRs M1-M5 and the conceivable off-target acetylcholinesterase. Five arecoline derivatives and arecoline were labeled with carbon-11 in good yields. Arecaidine diphenylmethyl ester (3b), arecaidine bis(4-fluorophenyl)methyl ester (3c) and arecaidine (4-bromophenyl)(4-fluorophenyl)methyl ester (3e) showed a tremendous gain in mAChR affinity compared to arecoline and a pronounced subtype selectivity for M1. Metabolic stability and serum protein binding of [C-11] 3b and [C-11] 3c were in line with properties of established brain tracers. Nonspecific binding of [C-11]3c was prevalent in kinetic and endpoint experiment on living cells as well as in autoradiography on native mouse brain sections, which motivates us to decrease the lipophilicity of this substance class prior to in vivo experiments. (C) 2020 The Author(s). Published by Elsevier Masson SAS.

COA of Formula: C13H13N. About Diphenylmethanamine, If you have any questions, you can contact Ozenil, M; Pacher, K; Balber, T; Vraka, C; Roller, A; Holzer, W; Spreitzer, H; Mitterhauser, M; Wadsak, W; Hacker, M; Pichler, V or concate me.

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Shen, MH; Li, C; Xu, QS; Guo, B; Wang, R; Liu, XQ; Xu, HD; Xu, DF in [Shen, Mei-Hua; Li, Chen; Xu, Qing-Song; Guo, Bin; Wang, Rui; Liu, Xiaoqian; Xu, Hua-Dong; Xu, Defeng] Changzhou Univ, Sch Pharm, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Jiangsu, Peoples R China published Allylation and alkylation of oxindoleketimines via imine umpolung strategy in 2021.0, Cited 77.0. SDS of cas: 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

When treated with an alkoxide base like t-BuOK in aprotic solvent, N-diphenylmethyl imino oxindoles, made conveniently through condensation of corresponding isatins with N-diphenylmethyl amine, are deprotonated to form azaallyl anions. Allylation and alkylation of this type of intermediates proceed smoothly with diverse C-electrophiles. Acidic work up finishes 3-amino-3-allyl/alkyl oxindoles. The overall transformation equals to an umpolung process at the C3 of isatins. (c) 2021 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

About Diphenylmethanamine, If you have any questions, you can contact Shen, MH; Li, C; Xu, QS; Guo, B; Wang, R; Liu, XQ; Xu, HD; Xu, DF or concate me.. SDS of cas: 91-00-9

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I found the field of Chemistry very interesting. Saw the article Development of a Large-Scale Route to Glecaprevir: Synthesis of the Macrocycle via Intramolecular Etherification published in 2020.0. Quality Control of Diphenylmethanamine, Reprint Addresses Cink, RD (corresponding author), AbbVie Inc, Proc Res & Dev, N Chicago, IL 60064 USA.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

Glecaprevir was identified as a potent hepatitis C virus (HCV) protease inhibitor, and a large-scale synthesis was required to support the late-stage clinical trials and subsequent commercial launch. The large-scale synthetic route to glecaprevir required the development of completely new synthetic approaches to the two key structural features: the 18-membered macrocycle 3 and the difluoromethyl-substituted cyclopropyl amino acid 4. In this first manuscript, we describe the route development for the macrocycle 3; the second manuscript will describe the development of a new synthetic route to the difluoromethyl-substituted cyclopropyl amino acid 4 and the final assembly of glecaprevir. The large-scale synthetic route to the macrocycle employed a unique intramolecular etherification reaction as the key step in the macrocycle synthesis, avoiding the scalability limitations of the ring-closing metathesis (RCM) reaction of the enabling route. The large-scale synthetic route to the macrocycle was successfully used to produce the amount of glecaprevir required to support the late-stage clinical development.

About Diphenylmethanamine, If you have any questions, you can contact Kallemeyn, JM; Engstrom, KM; Pelc, MJ; Lukin, KA; Morrill, WH; Wei, HJ; Towne, TB; Henle, J; Nere, NK; Welch, DS; Shekhar, S; Ravn, MM; Zhao, G; Fickes, MG; Ding, C; Vinci, JC; Marren, J; Cink, RD or concate me.. Quality Control of Diphenylmethanamine

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Authors Peng, K; Luo, Q; Zhang, YC; Xia, JB in ELSEVIER SCI LTD published article about SOLID-STATE SYNTHESIS; TEMPERATURE SENSOR; CATALYZED POLYCONDENSATION; CONJUGATED POLYMER; POLY(3,4-ETHYLENEDIOXYTHIOPHENE); POLY(IMINOARYLENE)S; POLYTHIOPHENE; CELLS in [Peng, Kai; Luo, Qi; Zhang, Yichi; Xia, Jiangbin] Wuhan Univ, Coll Chem & Mol Sci, Hubei Key Lab Organ & Polymer Optoelect Mat, Wuhan 430072, Peoples R China; [Xia, Jiangbin] Wuhan Univ, Coll Chem & Mol Sci, Minist Educ, Engn Res Ctr Organosilicon Cpds & Mat, Wuhan 430072, Peoples R China in 2020.0, Cited 42.0. Application In Synthesis of Diphenylmethanamine. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

C-Br/N-H bulk polycondensation is firstly proposed and corresponding poly(3,4-dinitm-thiophen-2-yl aryl-amine)s derivatives have been successfully obtained with quantitative yield. Typical crystal analysis reveals that its effective reaction points distance (RPD, distance between Br and H atom) is 5.083 angstrom, which is 66.7% longer than the sum of van der Waals radius (r(w)) of bromine and hydrogen atoms (3.05 angstrom). Carbazole-based monomer was explored as a thermalsensor with excellent relative sensitivity (S-a) of 0.45% K-1.

About Diphenylmethanamine, If you have any questions, you can contact Peng, K; Luo, Q; Zhang, YC; Xia, JB or concate me.. Application In Synthesis of Diphenylmethanamine

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics