Tag: M.W=100-150

Duan, Wenlong published the artcilePolymorphs and Transformations of the Solid Forms of Organic Salts of 5-Sulfosalicylic Acid and Isonicotinamide, Recommanded Product: Isonicotinamide, the publication is Crystal Growth & Design (2020), 20(12), 7606-7614, database is CAplus.

Diversities of salts formed by 5-sulfosalicylic acid (5-SSA) and isonicotinamide (INA) were obtained by mechanochem. grinding and from solution, including 3 polymorphs of (5-SSA-2H)^–·(INA-H)⁺·H₂O (1) (form 1a, form 1b, and form 1c), dehydration phase (5-SSA-2H)₂^–·(INA-H)₂⁺ (2), solvent phases (5-SSA-2H)^–·(INA-H)⁺·MeOH (3) and (5-SSA-2H)₂^–·(INA-H)₂⁺·H₂O·MeOH (4), and stoichiometric form (5-SSA-2H)^–·(INA-H)⁺·(INA) (5). The work studies not only the stabilities of the 3 polymorphs and the relation between solvated 1 and desolvation phase 2 but also the interconversion of these crystalline phases. The dehydrated phase 2 and solvent phase 4 comprising 2 independent 5-SSA anions and 2 independent INA cations in the asym. unit form an individual ion pair and the corresponding H bonded networks. The solvent phase (5-SSA-2H)₂^–·(INA-H)₂⁺·H₂O·MeOH (4) shows the individual structural features of both (5-SSA-2H)^–·(INA-H)⁺·H₂O (1) and solvent phase (5-SSA-2H)^–·(INA-H)⁺·MeOH (3). All 7 salts build up layered structures but comprising a different H bonding network and can experience a reversible transformation. Quantum mechanics calculations are used to assess the stability of some of the crystalline phases under study. The example of salts of 5-SSA and INA comprising a diversity of solid forms reported here can be considered very rare, which provided a good model for the insight into the structural transformation of materials of interest. Diversities of salts formed by 5-sulfosalicylic acid (5-SSA) and isonicotinamide (INA), including 3 polymorphs of (5-SSA-2H)^–·(INA-H)⁺·H₂O (1), dehydrated (5-SSA-2H)₂^–·(INA-H)₂⁺ (2), solvent phases (5-SSA-2H)^–·(INA-H)⁺·MeOH (3) and (5-SSA-2H)₂^–·(INA-H)₂⁺·H₂O·MeOH (4), and stoichiometric form (5-SSA-2H)^–·(INA-H)⁺·(INA) (5), were obtained, and their reversible transformations were discussed.

Crystal Growth & Design published new progress about 1453-82-3. 1453-82-3 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is Isonicotinamide, and the molecular formula is C6H6N2O, Recommanded Product: Isonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Zhou, Jianlin published the artcileDual Self-Healing Anticorrosion Coatings Based on Multibranched Waterborne Polyurethane and TiO₂ Nanocapsule-Loaded Graphene Oxide, Quality Control of 2479-62-1, the publication is Advanced Materials Interfaces (2022), 9(9), 2102001, database is CAplus.

The study reports the successful fabrication of a novel dual self-healing anticorrosion coating based on benzotriazole loaded TiO₂ nanocapsule (BTC) modified graphene oxide sheets and the multibranched waterborne polyurethane (WPU). When corrosion occurs, the benzotriazole (BZT) in nanocapsules can be slowly released from the coating forming a passivation layer on the metal surface to isolate the corrosive mediums. The anticorrosion performance of coating is examined by performing electrochem. tests. As indicated from the results, after being immersed in 3.5 wt% NaCl for 7 d, the prepared coating shows excellent anticorrosion performance with inhibition efficiency of 99%. In addition, the φ in 10⁴ Hz increases from 10° to 30°, and Log|Z|_0.01Hz remains at nearly 4.5 with the immersing time extended to 30 d. Moreover, when the coating is phys. damaged, the damaged coating can be self-repaired by the reversible disulfide bonds in WPU and the releasing of the BZT simultaneously. Compared with other control anticorrosion coatings, the healed coating achieves significantly improved anticorrosion performance, and the damaged coating can still sustain the original anticorrosion performance after self-healing. This study proposes a novel fabrication strategy for self-healing materials, and it can contribute to the long-term use of anticorrosion coatings.

Advanced Materials Interfaces published new progress about 2479-62-1. 2479-62-1 belongs to amides-buliding-blocks, auxiliary class Monomers,Acrylamide Monomers, name is N-(2-Amino-2-oxoethyl)acrylamide, and the molecular formula is C8H16O2, Quality Control of 2479-62-1.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Zhou, Jianlin published the artcileSelf-Healing Titanium Dioxide Nanocapsules-Graphene/Multi-Branched Polyurethane Hybrid Flexible Film with Multifunctional Properties toward Wearable Electronics, Application In Synthesis of 2479-62-1, the publication is Advanced Functional Materials (2021), 31(29), 2011133, database is CAplus.

The integration of self-healing capabilities into flexible electronics arouses extensive attention. The application of self-healing electronics with multifunctional properties in a variety of exceptional environments has been identified to be significantly challenging and not yet proven to be fully viable thus far. In the present study, the self-healing octadecane loaded titanium dioxide nanocapsules (OTNs)-graphene/multi-branched polyurethane (PU) hybrid flexible multifunctional film is successfully prepared The prepared film exhibits a novel self-repair capability that consists of disulfide bonds in the leading chains for efficient self-healing of PU damage, as well as multiple amino groups in the branches for damage between OTNs-graphene and PU. Impacted by the constructed self-healing system and well-dispersed OTNs-graphene, the prepared flexible film demonstrates a prominent performance in piezoresistive sensing and a desirable outcome of UV protection properties, which can effectively prolong its service life, especially when used outdoors. Moreover, the film exhibits thermal insulating properties, capable of offering a suitable route for thermal protection of bio-integrated wearable electronic devices system. Thus, this self-healing multifunctional film is promising in wearable electronics, human-machine interaction, artificial intelligence devices, etc.

Advanced Functional Materials published new progress about 2479-62-1. 2479-62-1 belongs to amides-buliding-blocks, auxiliary class Monomers,Acrylamide Monomers, name is N-(2-Amino-2-oxoethyl)acrylamide, and the molecular formula is C15H24S, Application In Synthesis of 2479-62-1.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Robichaud, Brian A. published the artcileTitanium isopropoxide/pyridine mediated Knoevenagel reactions, SDS of cas: 15029-36-4, the publication is Tetrahedron Letters (2011), 52(51), 6935-6938, database is CAplus.

A Ti(OiPr)₄-pyridine-mediated Knoevenagel reaction between aromatic ketones and cyanoacetamides to provide Knoevenagel olefin products in good to excellent yields was reported. Almost in all cases studied, a single geometrical isomer was formed and isolated under the Ti(OiPr)₄-pyridine condensation conditions. This methodol. was also demonstrated as highly effective process between some other Knoevenagel active methylene compounds and aromatic ketones.

Tetrahedron Letters published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C5H8N2O, SDS of cas: 15029-36-4.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Merlo, Thais Cardoso published the artcileRelationship between volatile organic compounds, free amino acids, and sensory profile of smoked bacon, Synthetic Route of 1453-82-3, the publication is Meat Science (2021), 108596, database is CAplus and MEDLINE.

Flavor is one of the most important characteristics of smoked bacon, strongly affecting its liking by consumers. The smoking process, lipid oxidation and proteolysis contribute to bacon quality through the generation of odors and flavor compounds In this study, the relationships between free amino acids (FAAs), volatile organic compounds (VOCs) and sensory characteristics of smoked bacon stored for 60 days at 5°C were investigated. Smoked bacon stored for 30 days was characterized by VOCs associated with the smoking process and lipid oxidation After 30 days of storage, the bacon samples presented an increase in FAAs produced mainly by proteolysis. Smoked bacon was characterized by the attributes smoky, crunchy, salty, soft and bright. This study demonstrated that VOCs, FAAs and their interactions are responsible for generating sensory attributes and increasing overall liking.

Meat Science published new progress about 1453-82-3. 1453-82-3 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is Isonicotinamide, and the molecular formula is C6H6N2O, Synthetic Route of 1453-82-3.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Hagelloch, G. published the artcileThe bacteria-inhibiting effectiveness of some compounds with the :NC(:S) group, Application In Synthesis of 14294-10-1, the publication is Zeitschrift fuer Naturforschung (1951), 147-55, database is CAplus.

The predicated ability of :NC(:S) to act as a chelating agent for heavy metals prompted the testing of homologous compounds against staphylococci, coli bacteria, pleuropneumonia-like organisms, and tubercle bacteria. The following related groups were tested on nutrient and serum agar: dithiocarbamates and derivatives, thioamides, thioöxamide and derivatives, NCS in heterocyclic compounds, thioureas, and thiobiurets and derivatives The majority of the substances investigated were completely effective in concentrations of less than 10 mg.%.

Zeitschrift fuer Naturforschung published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, Application In Synthesis of 14294-10-1.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Mitzner, Elke published the artcileFormylation products of thioamides. V. Synthesis of aminomethylene thioureas from substituted thioureas and formamide chlorides, Related Products of amides-buliding-blocks, the publication is Zeitschrift fuer Chemie (1983), 23(1), 19-20, database is CAplus.

Iminoformylation of R¹R²NC(S)NH₂ [R¹R² = CH₂CH₂OCH₂CH₂, (CH₂)₄, R¹ = Ph, R² = H] with a mixture of HCONR₂³ [R₂³ = (CH₂)₅, Me₂, CH₂CH₂OCH₂CH₂, (CH₂)₄] gave 32-71% (aminomethylene)thioureas R¹R²NC(S)NCHNR₂³. Attempts to prepare PhNMeC(S)N:CHNR₂³ [R₂³ = (CH₂)₄] gave 21% of the hydrolysis product PhNMeN(S)NHCHO. Thiazoles I [R¹R² = CH₂CH₂OCH₂CH₂, R = Br, H; R¹R² = (CH₂)₄, R = Cl] were prepared by cyclizing R¹R²NC(S)N:CHNR₂³ with BrCH₂COC₆H₄R-4.

Zeitschrift fuer Chemie published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, Related Products of amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Liu, Hongji published the artcileBergenin-isonicotinamide (1:1) cocrystal with enhanced solubility and investigation of its solubility behavior, SDS of cas: 1453-82-3, the publication is Journal of Drug Delivery Science and Technology (2021), 102556, database is CAplus.

Bergenin (BER) is a bioactive compound used for the treatment of chronic bronchitis in China. However, its low solubility and permeation limits its oral bioavailability. In this study, a new BER: isonicotinamide (ISN) cocrystal (1: 1, molar ratio) was reported for the first time. BER-ISN shows better solubility and intrinsic dissolution rates (IDRs) in aqueous medias such as water, buffer solutions with pH = 1.2, 4.5, and 6.8 in comparison to BER monohydrate. For instance, the solubilities of BER-ISN and BER monohydrate in water were 3.72 ± 0.22 and 1.42 ± 0.006 mg/mL, resp., showing 2.62 times improvement. IDRs of BER-ISN and BER monohydrate were 29.90 ± 0.04 and 18.64 ± 0.27 mg/min/cm₂, resp., which was consistent with the solubility results. To explain the solubility behavior, phase solubility diagrams of BER monohydrate, ISN and BER-ISN in three pure organic solvents (ethanol, isopropanol and Et acetate) were performed according to the solubility product (Ksp) and complexes formation (K11) theory. The predicted solubilities are consistent with exptl. solubilities considering complexation effects. The Hildebrand solubility parameter (HSP) calculations support the results. Thus, BER-ISN cocrystal (1: 1) with improved solubility is a good candidate for further formulation development.

Journal of Drug Delivery Science and Technology published new progress about 1453-82-3. 1453-82-3 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is Isonicotinamide, and the molecular formula is C6H6N2O, SDS of cas: 1453-82-3.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Seng, Florin published the artcile2-Aminocarbonyl-1-hydroxybenzimidazole 3-oxides, Application In Synthesis of 15029-36-4, the publication is Synthesis (1972), 606, database is CAplus.

The 1-hydroxybenzimidazole 3-oxides I (R = H, Cl, Me, OMe; R1 = H, Me, Et, Ph, cyclohexyl) were prepared in 32-92% yield by treating the corresponding benzofuroxans with NCCH2CONHR1 and aqueous NaOH to precipitate the Na salts of I. Acidification of the Na salts yielded free I.

Synthesis published new progress about 15029-36-4. 15029-36-4 belongs to amides-buliding-blocks, auxiliary class Nitrile,Amine,Aliphatic hydrocarbon chain,Amide, name is 2-Cyano-N-ethylacetamide, and the molecular formula is C15H19BO2, Application In Synthesis of 15029-36-4.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Li, Jianting published the artcileStructural landscape investigations on bendable plastic crystals of isonicotinamide polymorphs, Related Products of amides-buliding-blocks, the publication is Chinese Chemical Letters, database is CAplus.

Three polymorphs (forms I, II and V) of isonicotinamide (INA) were mech. flexible and exhibited 1-dimensional (1D) plasticity. Anisotropic intermol. interactions contribute to the plasticity of single crystals: weak dispersive interactions between slip planes such as 1D columns in forms I and II or 2D layers in form V were stabilized by strong H bonds, allowing the layer or column′s surface to glide smoothly without hindrance. The disparity of intermol. interactions on plastic properties of INA polymorphic crystals was confirmed by energy framework anal., nanoindentation tests and micro-Raman spectroscopy.

Chinese Chemical Letters published new progress about 1453-82-3. 1453-82-3 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is Isonicotinamide, and the molecular formula is C6H6N2O, Related Products of amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics