Tag: 300-400

Sapozhnikova, Yelena;Nunez, Alberto;Johnston, John Retired published 《Screening of chemicals migrating from plastic food contact materials for oven and microwave applications by liquid and gas chromatography – Orbitrap mass spectrometry》 in 2021. The article was appeared in 《Journal of Chromatography A》. They have made some progress in their research.SDS of cas: 112-84-5 The article mentions the following:

Contamination of food with chems. migrating from food contact materials (FCMs) is an important area of food safety. This study was aimed to investigate migration of chems. from plastic FCMs used for microwave and conventional oven heating. Migration tests were conducted for samples of microwave trays, microwave oven bags, and oven bags. GC- and LC-Orbitrap mass spectrometry (MS) was used for non-targeted screening and identification of chems. with mass error <5 ppm. A non-targeted identification approach was validated with isotopically labeled chems. to establish acceptable criteria for identification of migrated compounds A total of 74 migrated compounds were tentatively identified: 24 chems. by GC-Orbitrap MS with electron ionization (EI), plus 35 and 19 by LC-Orbitrap MS electrospray ionization (ESI) with pos. and neg. polarities, resp. Four migrated chems. were identified by more than one instrumental anal. Both intentionally added substances (IAS), i.e. additives used in the production of polymeric materials and plastics, and non-intentionally added substances (NIAS), i.e. derivatives and degradation/oxidation products of IAS, were identified among the migrated chems. The levels of 25 migrated chems. were significantly different (p < 0.05) between microwave treatments and conventional oven treatments, where 20 migrants had higher levels for microwave compared with 5 for conventional oven treatments. For several identified chems., no previous reports on their migration from FCMs were found. The experimental procedure involved many compounds, such as cis-13-Docosenamide (cas: 112-84-5) .

cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.SDS of cas: 112-84-5 It has a role as a human metabolite, a rat metabolite, a mammalian metabolite, a plant metabolite and an EC 3.1.1.7 (acetylcholinesterase) inhibitor.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Prasathkumar, Murugan;Raja, Kannan;Vasanth, Krishnan;Khusro, Ameer;Sadhasivam, Subramaniam;Sahibzada, Muhammad Umar Khayam;Gawwad, Mohamed Ragab Abdel;Al Farraj, Dunia A.;Elshikh, Mohamed S. published 《Phytochemical screening and in vitro antibacterial, antioxidant, anti-inflammatory, anti-diabetic, and wound healing attributes of Senna auriculata (L.) Roxb. leaves》 in 2021. The article was appeared in 《Arabian Journal of Chemistry》. They have made some progress in their research.Recommanded Product: 112-84-5 The article mentions the following:

This study was aimed to determine total phytochem. components as well as in vitro antibacterial, antioxidant, anti-inflammatory, anti-diabetic, and wound healing attributes of Senna auriculata (L.) Roxb. leaves extract Among different solvent extracts tested, methanolic extract revealed maximum alkaloid, flavonoids, phenolic, and tannin contents of 90.41 ± 0.15 mg atropine equivalent/g, 156.64 ± 0.97 mg quercetin equivalent/g, 155.44 ± 1.65 mg gallic acid equivalent/g, and 121.31 ± 2.34 mg gallic acid equivalent/g of extract, resp. Antibacterial activity of methanolic extract was determined against indicator pathogens using agar well diffusion assay which exhibited potential activity against Bacillus subtilis. Antioxidant, anti-inflammatory, anti-diabetic, and wound healing attributes of methanolic extract were analyzed using standard methodologies. The extract exhibited potential antioxidant traits by scavenging ABTS (IC₅₀ value – 224.2 μg/mL) and DPPH (IC₅₀ value – 76.24 μg/mL) in a concentration dependent manner. Further, the extract demonstrated significant anti-inflammatory activities at varied doses with IC₅₀ value of 55.7 μg/mL. The methanolic extract exhibited promising rates of α-amylase and α-glucosidase inhibition with IC₅₀ values of 49.45 and 38.72 μg/mL, resp. Further, the extract showed no toxicity on L929 mouse fibroblast cell lines (99.66 ± 0.14% cell viability). Most importantly, the treatment of cell monolayer of L929 mouse fibroblast cell lines with methanolic extract showed high rate (100%) of wound healing trait. GC-MS anal. of methanolic extract revealed the presence of Mome inositol, 13-Docosenamide, (Z)-, Cycloheptasiloxane, tetradecamethyl-, and Octadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester as predominant compounds In conclusion, the biol. properties of S. auriculata leaves suggested its vast role as ideal antibacterial, antioxidant, anti-inflammatory, anti-diabetic, and wound healing agents in future. The experimental procedure involved many compounds, such as cis-13-Docosenamide (cas: 112-84-5) .

cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.Recommanded Product: 112-84-5 It is commonly used as a slip additive in the plastic manufacturing industry.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wang, Jifeng;He, Min;Guo, Wenjun;Zhang, Yanhong;Sui, Xin;Lin, Jianan;Liu, Xiaoran;Li, Hui;Li, Jing;Yang, Qing;Kan, Mo;Zhang, Zhuang;Ming, Sitong;Qu, Xiaobo;Li, Na published 《Microbiome-metabolomics reveals endogenous alterations of energy metabolism by the dushen tang to attenuate D-galactose-induced memory impairment in rats》 in 2021. The article was appeared in 《BioMed Research International》. They have made some progress in their research.Formula: C22H43NO The article mentions the following:

Aging affects the brain function in elderly individuals, and Dushen Tang (DST) is widely used for the treatment of senile diseases. In this study, the protective effect of DST against memory impairment was evaluated through the Morris water maze (MWM) test and transmission electron microscopy (TEM). A joint anal. was also performed using LC-MS metabolomics and the microbiome. The MWM test showed that DST could significantly improve the spatial memory and learning abilities of rats with memory impairment, and the TEM anal. showed that DST could reduce neuronal damage in the hippocampus of rats with memory impairment. Ten potential biomarkers involving pyruvate metabolism, the synthesis and degradation of ketone bodies, and other metabolic pathways were identified by the metabolomic anal., and it was found that 3-hydroxybutyric acid and lactic acid were involved in the activation of cAMP signaling pathways. The 16S rDNA sequencing results showed that DST could regulate the structure of the gut microbiota in rats with memory impairment, and these effects were manifested as changes in energy metabolism These findings suggest that DST exerts a good therapeutic effect on rats with memory impairment and that this effect might be mainly achieved by improving energy metabolism These findings might lead to the potential development of DST as a drug for the treatment of rats with memory impairment.cis-13-Docosenamide (cas: 112-84-5) were involved in the experimental procedure.

cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.Formula: C22H43NO It is commonly used as a slip additive in the plastic manufacturing industry.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Gubala, Dajana;Fox, Laura J.;Harniman, Robert;Hussain, Hadeel;Robles, Eric;Chen, Meng;Briscoe, Wuge H. published 《Heads or tails: Nanostructure and molecular orientations in organised erucamide surface layers》 in 2021. The article was appeared in 《Journal of Colloid and Interface Science》. They have made some progress in their research.Product Details of 112-84-5 The article mentions the following:

Despite the widespread industrial usage of erucamide as a slip additive to modify polymer surface properties, a controversy appears to have persisted regarding the nanostructure of erucamide surface layers, particularly the mol. orientation at the outermost layer. The erucamide nanostructure and mol. orientation, along with its surface coverage, hydrophobicity, and adhesive response, can be tuned by simply varying the erucamide concentration in the solution from which the spin coated layer is prepared Synchrotron X-ray reflectivity (XRR) allowed a comprehensive characterization of the out-of-plane structural parameters (e.g. mol. packing and thickness) of the erucamide layers prepared via spin coating from nonaqueous solution on silica. Complementary Atomic Force Microscopy (AFM) imaging with high lateral resolution revealed localised in-plane structures. Contact angle measurements provided information on the wettability of erucamide-coated surfaces. Peak Force Quant. Nanomech. Mapping (QNM) allowed a correlation between the erucamide nanostructure with the surface nanomech. properties (i.e. adhesive response). Our results reveal erucamide surface nanostructures on silica as patchy monolayers, isolated circular bilayers/rounded rectangle-like aggregates and overlapping plate-like multilayers as the erucamide concentration in the spin coating solution was varied. In all the cases, XRR and AFM results were consistent with the picture that the erucamide tails were oriented outwards. The QNM adhesion force mapping of all the observed morphologies also supported this mol. orientation at the outermost erucamide monolayer. The wettability study further confirmed this conclusion with the observed increase in the surface hydrophobicity and coverage upon increasing erucamide concentration, with the macroscopic water contact angle θ = 92.9° ± 2.9° at the highest erucamide concentration of 2 wt%.cis-13-Docosenamide (cas: 112-84-5) were involved in the experimental procedure.

cis-13-Docosenoamide(cas: 112-84-5) was employed as: standard in determination of fatty acid amides in polyethylene packaging film by GC/MS;slip agent for polymers to reduce their friction coefficient and to make films easier to handle.Product Details of 112-84-5

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Recommanded Product: cis-13-Docosenamide《Effects of nanocrystallization on surface migration of polypropylene/slip agent composites in accelerated aging》 was published in 2022. The authors were Won, Jong Sung;Lee, Jae Min;Lee, Pil Gyu;Choi, Hyeong Yeol;Kwak, Tae Joon;Lee, Seung Goo, and the article was included in《Journal of Materials Science》. The author mentioned the following in the article:

The accelerated thermal aging of plastics causes the migration of additives onto specimen surfaces. This is commonly called the “blooming” or “whitening” phenomenon and has long been an issue in the automotive applications of thermoplastic composites. Still, there is a lack of scientific reports regarding crystallization behavior to our best knowledge. This study investigates the mechanism and characteristics of slip agent migration onto injection-molded composite surfaces depending on the behavior of nanocrystn. with thermal aging and develops a method to evaluate the correlation between the internal and external crystallization size and migration of the composites. Slip agent migration was investigated by increasing the spherulite size of PP/slip agent composites, as measured by X-ray diffraction anal. at different periods. It was found that as the crystalline area increased, the low mol. weight slip agents present in the amorphous region migrated to the specimen surface owing to the absence of interactions with the polymer. In addition, surface elemental anal., lightness, and roughness confirmed that the slip agents migrated to the surface in accelerated thermal aging conditions. The findings of this work provide a better understanding of the correlation between thermal aging and the migration phenomenon of slip agents on the surfaces of thermoplastic composites.cis-13-Docosenamide (cas: 112-84-5) were involved in the experimental procedure.

cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.Recommanded Product: cis-13-Docosenamide It is commonly used as a slip additive in the plastic manufacturing industry.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Safety of cis-13-Docosenamide《Anti-inflammatory and anti-asthmatic effects of TMDCT decoction in eosinophilic asthma through Treg/ Th17 balance》 was published in 2022. The authors were Zhou, Yumei;Zhao, Haihong;Wang, Tieshan;Zhao, Xiaoshan;Wang, Ji;Wang, Qi, and the article was included in《Frontiers in Pharmacology》. The author mentioned the following in the article:

Tuo-Min-Ding-Chuan decoction (TMDCT) is a Traditional Chinese Medicine (TCM) formula consisting of twelve herbs that can relieve the symptoms and treat allergic asthma. Yet, the underlying mechanism of action is still unclear. In this study, we investigated the effect of TMDCT in regulating Treg/Th17 cells immune balance and explored potential metabolic and gut biomarkers associated with Treg and Th17 cells in eosinophilic asthma mice treated by TMDCT. We found that TMDCT increases Treg cells percentage and decreases Th17 cells percentage in the ovalbumin (OVA) -induced eosinophilic asthma mice model. Furthermore, Imidazoleacetic acid, DL-glutamine, L-pyroglutamic acid, 2-deoxy-D-glucose were preliminary identified as biomarkers in plasma metabolites treated by TMDCT, meanwhile genus Desulfovibrio, genus Butyricimonas and genus Prevotella 9 were preliminary identified as gut microbiota biomarkers after TMDCT treatment. These results provide an exptl. foundation for the treatment of allergic asthma with Chinese herbal compoundscis-13-Docosenamide (cas: 112-84-5) were involved in the experimental procedure.

cis-13-Docosenoamide(cas: 112-84-5) was employed as: standard in determination of fatty acid amides in polyethylene packaging film by GC/MS;slip agent for polymers to reduce their friction coefficient and to make films easier to handle.Safety of cis-13-Docosenamide

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zhang, Xin;Zheng, Yuanrong;Zhou, Ran;Ma, Ming published 《Comprehensive identification of molecular profiles related to sensory and nutritional changes in Mongolian cheese during storage by untargeted metabolomics coupled with quantification of free amino acids》 in 2022. The article was appeared in 《Food Chemistry》. They have made some progress in their research.Application of 112-84-5 The article mentions the following:

Non-targeted metabolomics was used to study metabolites with low mol. weight which may contribute to quality deterioration of Mongolian cheese during storage. Microbiol. anal., pH, FAAs (free amino acids), volatile compounds, and sensory evaluation of the cheese during storage were also studied. A total of 278 metabolites were identified in Mongolian cheese, of which 51 metabolites were used as differential metabolites, including amino acids, peptides, organic acids, lipids, and carbohydrates. Bitter amino acids, bitter peptide (Phe-Ile), and organic acids (sinapic acid, butyric acid) increased during storage. Metabolic pathway anal. showed that differential metabolites were mainly related to amino acid metabolism, such as β-alanine metabolism and glycine, serine, and threonine metabolism Moreover, accompanied with the increased contents of short-chain fatty acids, 2-undecanone and Et esters, strength of odor and unpleasant smell increased but overall acceptability decreased during Mongolian cheese storage. This research provides suitable strategies for quality control of Mongolian cheese during shelf life.cis-13-Docosenamide (cas: 112-84-5) were involved in the experimental procedure.

cis-13-Docosenoamide(cas: 112-84-5) was employed as: standard in determination of fatty acid amides in polyethylene packaging film by GC/MS;slip agent for polymers to reduce their friction coefficient and to make films easier to handle.Application of 112-84-5

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

COA of Formula: C22H43NOIn 2022, Chen, Zhi-Feng;Lin, Qin-Bao;Dong, Ben;Zhong, Huai-Ning;Wang, Zhi-Wei published 《Comparison of the ability of UV-Vis and UPLC-Q-TOF-MS combined with chemometrics to discriminate recycled and virgin polyethylene》. 《Journal of Hazardous Materials》published the findings. The article contains the following contents:

A growing attention is attracted to the use of recycled plastics as food contact materials, and its chem. safety research and discrimination approach are indispensable. In current study, UV-visible spectrometry (UV-Vis) and ultra-performance liquid chromatog. quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) were used to provide spectral and mass fingerprinting for polyethylene (PE). Coupling with chemometrics, two methods were developed to discriminate recycled and virgin PE. UV-Vis combined with chemometrics could be a more accessible, simpler and faster approach. 237-331 nm in UV spectrum was regarded as marker region selected by orthogonal partial least-squares discrimination anal. (OPLS-DA) and the accuracy of both calibration and validation set could reach 100% in linear discrimination anal. (LDA) based on this region. Besides, 2314 ions were detected by UPLC-Q-TOF-MS and processed by MS-DIAL. 48 candidate chems. were identified, including ketone, esters, carboxylic acid, alcs. and phenols, amine, nitriles, aldehydes and others. Possible origins of these compounds could be classified as plastic, food, drug, cosmetics and pesticide related. Many of these compounds are highly toxic, especially pesticide related, indicating that recycling in closed loop or sorting by the recycled plastic articles is very necessary if the recycled PE is going to be used as food contact material. To complete the study, the researchers used cis-13-Docosenamide (cas: 112-84-5) .

cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.COA of Formula: C22H43NO It has a role as a human metabolite, a rat metabolite, a mammalian metabolite, a plant metabolite and an EC 3.1.1.7 (acetylcholinesterase) inhibitor.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Formula: C22H43NOIn 2021, Cui, Huan;Gao, Weichang;Lin, Yechun;Zhang, Jie;Yin, Runsheng;Xiang, Zhangmin;Zhang, Song;Zhou, Shuping;Chen, Wensheng;Cai, Kai published 《Development of microwave-assisted extraction and dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry for determination of organic additives in biodegradable mulch films》. 《Microchemical Journal》published the findings. The article contains the following contents:

Organic additives are extensively used as ingredients in biodegradable mulch films. They are swiftly released into the environment, which may have an ecotoxicol. impact on plant growth and development, as well as on soil microbial community abundance and function. Herein, a method based on the application of microwave-assisted extraction (MAE) and dispersive liquid-liquid microextraction (DLLME) was developed to analyze eighty organic additives by gas chromatog.-mass spectrometry in poly(butylene adipate terephthalate) (PBAT) biodegradable mulch films. This was a comprehensive study, including the identification of organic additives, optimization of MAE and DLLME methods, anal. of isocyanate conversion, and evaluation of the matrix effect (ME). Under the optimized exptl. conditions, this method exhibited excellent detection capabilities for organic additives, except for 5 kinds of isocyanates and their reaction products, with coefficients of determination R² > 0.999 and lack of fit P > 0.05 in linear regression parameters. A negligible ME was observed The relative recoveries were 93.0-109.8%, and the repeatability and reproducibility varied within the ranges of 2.06-8.76% and 2.38-10.23%, resp. The limits of detection and limits of quantitation were 0.0008-0.0586μg g^-1 and 0.003-0.195μg g^-1, resp. The developed method was further successfully applied to the anal. of organic additives in PBAT biodegradable mulch films from four different manufacturers. Interestingly, the Venn diagram and principal component anal. showed that different manufacturing origins display obvious characteristic differences in the organic additive types and concentrationscis-13-Docosenamide (cas: 112-84-5) were involved in the experimental procedure.

cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.Formula: C22H43NO It is commonly used as a slip additive in the plastic manufacturing industry.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthetic Route of C22H43NOIn 2021, Power, Andrew;White, Philip;McHugh, Brendan;McGovern, Evin;Murphy, Sinead;Berrow, Simon;Schlingermann, Moira;Gately, Cillian;Tannian, Marissa;Newton, Stephen;Crowley, Denis;O′Hea, Linda;Boyle, Brian;O′Connor, Ian published 《Legacy and emerging contaminants in common guillemot Uria aalge eggs in Ireland and Wales》. 《Chemosphere》published the findings. The article contains the following contents:

Guillemot eggs from multiple Irish colonies and one Welsh colony were analyzed for legacy pollutants such as polychlorinated biphenyls (PCBs), polybrominated di-Ph ethers (PBDEs) and other organochlorine compounds (OCs), as well as metals. Stable isotope ratios of carbon (δ¹³C) and nitrogen (δ¹⁵N) were measured in eggs to understand the influence of diet on contaminant levels detected. Wide-scope target and suspect screening techniques were used on a single guillemot egg, providing novel information on contaminants of emerging concern. Stable isotope ratio anal. showed that guillemots from Great Saltee Island and Lambay Island (Ireland′s east coast) had a similar carbon source (δ¹³C) and fed at similar trophic levels (δ¹⁵N), pollutant levels were higher in eggs from Lambay Island near Dublin, Ireland′s industrialised capital city. Guillemot eggs from Aughris Head (Atlantic west coast of Ireland), and Skomer Island (Wales) had differing isotopic niches to other colonies. Egg samples from Aughris Head had the lowest levels of pollutants in this study (with the exception of mercury) and amongst the lowest levels reported worldwide. In contrast, Skomer Island had the highest level of pollutants with higher concentrations of Σ16PCB, Σ6PBDE and HCB than Irish colonies, most likely a result of its proximity to historically industrial areas. Levels of PCBs, p,p′ -DDE and mercury in guillemot eggs have decreased over time according to this study, in concurrence with worldwide trends. Levels of pollutants in guillemot eggs, in this study, fall below existing thresholds for adverse effects in other species, with the exception of mercury. And cis-13-Docosenamide (cas: 112-84-5) was used in the research process.

cis-13-Docosenoamide(cas: 112-84-5) is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia.Synthetic Route of C22H43NO It has a role as a human metabolite, a rat metabolite, a mammalian metabolite, a plant metabolite and an EC 3.1.1.7 (acetylcholinesterase) inhibitor.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics