Tag: 200-300

Mass spectra of N-aryl(arylsulfonyl)-4-aminophenols (-naphthols) was written by Avdeenko, A. P.. And the article was included in Voprosy Khimii i Khimicheskoi Tekhnologii in 1988.COA of Formula: C13H13NO3S This article mentions the following:

The mass spectra of title compounds I (R = Ph, p-tolyl, 2-naphthyl; R¹ = H, Cl, CHMe₂; R² = H, Cl; R³ = H, Me), II (R = H, Me; R¹ = H, SO₂Ph, Cl), and III (R = R¹ = H, Cl; R = Cl, R¹ = H) at 12 and 70 eV were analyzed. The most characteristic decomposition path for the mol. ions of I is ejection of the arylsulfonyl radical. In the experiment, the researchers used many compounds, for example, N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6COA of Formula: C13H13NO3S).

N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.COA of Formula: C13H13NO3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Debenzylative Sulfonylation of Tertiary Benzylamines Promoted by Visible Light was written by Fu, Ying;Wu, Qing-Kui;Du, Zhengyin. And the article was included in European Journal of Organic Chemistry in 2021.Related Products of 383-31-3 This article mentions the following:

An efficient, general, inexpensive, and environmentally friendly photosynthesis of sulfonamides via visible light promoted debenzylative sulfonylation of tertiary benzylamines is described. Compared to the traditional S-N coupling reactions, which are promoted by oxidative C-N bond cleavage of sym. tertiary alkylamines, this strategy provides a selective C-N bond cleavage protocol and avoids the use of transition-metal, explosive oxidants, and ligands. In the experiment, the researchers used many compounds, for example, 4-Fluoro-N,N-dimethylbenzenesulfonamide (cas: 383-31-3Related Products of 383-31-3).

4-Fluoro-N,N-dimethylbenzenesulfonamide (cas: 383-31-3) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Related Products of 383-31-3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Silver Recovery from Laundry Washwater: The Role of Detergent Chemistry was written by Nawaz, Tabish;Sengupta, Sukalyan. And the article was included in ACS Sustainable Chemistry & Engineering in 2018.Synthetic Route of C10H16N2O4 This article mentions the following:

The use of Ag nanoparticles as an antimicrobial agent on textiles is rising. Ag leaching during laundry and its subsequent discharge in the environment pose ecotoxicol. risks. Removing Ag from laundry washwater is therefore an environmental necessity, but its recovery also leads to environmental sustainability. Low Ag concentration, competition from other cations (such as Ca²⁺, Mg²⁺, and Na⁺), and complexity of the detergent matrix make the recovery process challenging. This study uses a thiol-group functionalized ion-exchange resin in a fixed-bed column to remove Ag from laundry washwater and recover it as Ag₂S nanoparticles or high-purity powder. The role of each detergent component in affecting Ag speciation and the resin performance was analyzed. Builders and bleaching agents are reported to neg. impact the resin performance; pH and cocationic species (Ca²⁺) concentration are critical parameters for the successful recovery. This work demonstrates a closed-loop sustainable scheme by recycling and reusing the resin and the regenerant solution over 5 cycles. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Synthetic Route of C10H16N2O4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Synthetic Route of C10H16N2O4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

C-H Oxygenation Reactions Enabled by Dual Catalysis with Electrogenerated Hypervalent Iodine Species and Ruthenium Complexes was written by Massignan, Leonardo;Tan, Xuefeng;Meyer, Tjark H.;Kuniyil, Rositha;Messinis, Antonis M.;Ackermann, Lutz. And the article was included in Angewandte Chemie, International Edition in 2020.COA of Formula: C9H10BrNO2 This article mentions the following:

The catalytic generation of hypervalent iodine(III) reagents by anodic electrooxidation was orchestrated towards an unprecedented electrocatalytic C-H oxygenation of weakly coordinating aromatic amides and ketones. Thus, catalytic quantities of iodoarenes in concert with catalytic amounts of ruthenium(II) complexes set the stage for versatile C-H activations with ample scope and high functional group tolerance. Detailed mechanistic studies by experiment and computation substantiate the role of the iodoarene as the electrochem. relevant species towards C-H oxygenations with electricity as a sustainable oxidant and mol. hydrogen as the sole byproduct. Para-Selective C-H oxygenations likewise proved viable in the absence of directing groups. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2COA of Formula: C9H10BrNO2).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.COA of Formula: C9H10BrNO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner-Wadsworth-Emmons olefination/cyclisation was written by Muir, Calum W.;Kennedy, Alan R.;Redmond, Joanna M.;Watson, Allan J. B.. And the article was included in Organic & Biomolecular Chemistry in 2013.Application In Synthesis of 4-Bromo-N-methoxy-N-methylbenzamide This article mentions the following:

4H-Quinolizin-4-ones are a unique class of heterocycle with valuable physicochem. properties and which are emerging as key pharmacophores for a range of biol. targets. A tandem Horner-Wadsworth-Emmons olefination/cyclization method has been developed to allow facile access to substituted 4H-quinolizin-4-ones encoded with a range of functional groups. E.g., tandem Horner-Wadsworth-Emmons olefination/cyclization of 1-phenyl-2-(pyridin-2-yl)ethanone (I) with tri-Et phosphonoacetate gave 92% 4H-quinolizin-4-one derivative (II). I was prepared as 3:1 keto:enol and approx. 3.8:1 enol olefin stereoisomers. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Application In Synthesis of 4-Bromo-N-methoxy-N-methylbenzamide).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Application In Synthesis of 4-Bromo-N-methoxy-N-methylbenzamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Fluoro-Substituted Methyllithium Chemistry: External Quenching Method Using Flow Microreactors was written by Colella, Marco;Tota, Arianna;Takahashi, Yusuke;Higuma, Ryosuke;Ishikawa, Susumu;Degennaro, Leonardo;Luisi, Renzo;Nagaki, Aiichiro. And the article was included in Angewandte Chemie, International Edition in 2020.HPLC of Formula: 116332-61-7 This article mentions the following:

The external quenching method based on flow microreactors allows the generation and use of short-lived fluoro-substituted methyllithium reagents, such as fluoromethyllithium, fluoroiodomethyllithium, and fluoroiodostannylmethyllithium. Highly chemoselective reactions were developed, opening new opportunities in the synthesis of fluorinated mols. using fluorinated organometallics. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7HPLC of Formula: 116332-61-7).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.HPLC of Formula: 116332-61-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Decolorization kinetics and properties of triphenodioxazine reactive dyes in sodium perborate-TAED bleaching system was written by Zhang, Jun;Zhu, Yang. And the article was included in Advanced Materials Research (Durnten-Zurich, Switzerland) in 2012.Recommanded Product: 10543-57-4 This article mentions the following:

The decolorization behaviors of a triphenodioxazine reactive dye (C.I. Reactive Blue 198) in the activated oxygen bleach system containing sodium perborate (PB) and tetra-acetylethylenediamine (TAED) were investigated. The decolorization kinetics of the dye was found to follow the first-order kinetic model and the rate constant of decolorization increased significantly with increasing temperature The activation energy for decolorizing reaction was 50.41 kJ/mol. The highest rate constant appeared at pH 8. The triphenodioxazine reactive dye showed poor stability to activated oxygen washing. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Recommanded Product: 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Recommanded Product: 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Low temperature bleaching of cotton cheese with peroxide activator TAED was written by Shi, Wen-zhao;Xing, Jian-wei;Ren, Zhi-gang;Xu, Cheng-shu;Liu, Jin-shu. And the article was included in Yinran in 2013.Reference of 10543-57-4 This article mentions the following:

This paper aiming at the high energy consumption and fiber damage in traditional high-temperature scouring and bleaching pretreatment of cotton cheese, low-temperature pretreatment process with tetra acetyl ethylene diamine (TAED) is introduced. The effect of dosages of hydrogen peroxide and TAED, caustic soda, temperature and time on whiteness, capillary effect and tensile strength is discussed and compared with that of traditional process. The results show that the optimal process conditions are NaOH 2 g/L, H₂O₂ (30%) 6 g/L, TAED 6 g/L, treating at 60 °C for 10 min, and then holding at 80 °C for 30 min. The yams pretreated with optimal process feature higher breaking strength, similar whiteness and capillary effect, shortened process time and procedure. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Reference of 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Reference of 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Phytosterol recognition via rationally designed molecularly imprinted polymers was written by Schwarz, Lachlan J.;Leung, Brenda K. Y.;Danylec, Basil;Harris, Simon J.;Boysen, Reinhard I.;Hearn, Milton T. W.. And the article was included in C in 2018.Category: amides-buliding-blocks This article mentions the following:

Molecularly imprinted polymers (MIPs) prepared via a semi-covalent imprinting strategy using stigmasteryl methacrylate as a polymerizable template have been evaluated by static binding methods for their ability to selectively capture other valuable phytosterol targets, including campesterol and brassicasterol. Design criteria based on mol. modeling procedures and interaction energy calculations were employed to aid the selection of the co-monomer type, as well as the choice of co-monomer:template ratios for the formation of the pre-polymerization complex. These novel hybrid semi-covalently imprinted polymers employed N,N’-dimethylacryl-amide (N,N’-DMAAM) as the functional co-monomer and displayed specific binding capacities in the range 5.2-5.9 mg sterol/g MIP resin. Their binding attributes and selectivities towards phytosterol compounds were significantly different to the corresponding MIPs prepared via non-covalent procedures or when compared to non-imprinted polymers. Cross-reactivity studies using stigmasterol, ergosterol, cholesterol, campesterol, and brassicasterol as single analytes revealed the importance of the A-ring C-3-β-hydroxyl group and the orientational preferences of the D-ring alkyl chain structures in their interaction in the templated cavity with the N,N’-dimethylamide functional groups of the MIP. Finally, to obtain useful quantities of both campersterol and brassicasterol for these investigations, improved synthetic routes have been developed to permit the conversion of the more abundant, lower cost stigmasterol via a reactive aldehyde intermediate to these other sterols. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Category: amides-buliding-blocks).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Graphene Oxide: A Metal-Free Carbocatalyst for the Synthesis of Diverse Amides under Solvent-Free Conditions was written by Patel, Khushbu P.;Gayakwad, Eknath M.;Patil, Vilas V.;Shankarling, Ganapati S.. And the article was included in Advanced Synthesis & Catalysis in 2019.HPLC of Formula: 2387-23-7 This article mentions the following:

An environment-friendly, inexpensive, carbocatalyst, graphene oxide (GO) which promoted efficient, metal-free transamidation of various carboxamides RC(O)NH₂ (R = Ph, pyridin-2-yl, H, Me, etc.) with aliphatic, cyclic, and aromatic amines NH(R¹)(R²) [R¹ = H, Ph; R² = n-Bu, Ph, cyclohexyl, pyridin-2-yl, etc.; R¹R² = -(CH₂)₄-, -CH₂CH₂OCH₂CH₂-] and 2-aminothiophenol is demonstrated. The protocol is equally applicable to phthalimides such as 1H-isoindole-1,3(2H)-dione, 5-methyl-1H-isoindole-1,3(2H)-dione, ureas R³NHC(O)NH₂ (R³ = H, Ph), and thioamide determining its adaptability. The oxygenated functionalities such as carbonyl (-C=O), epoxy (-O-), carboxyl (-COOH) and hydroxyl (-OH), present on graphene oxide surface impart acidic properties to the catalyst. The graphene oxide being heterogeneous in nature, work efficiently under solvent-free reaction conditions providing desired products RC(O)N(R¹)(R²), I, R¹NHC(O)NHR² in good to excellent yields. The one-pot synthesis of 2,3-dihydro-5H-benzo[b]-1,4-thiazepin-4-one moiety by GO catalyzed Aza Michael addition followed by intramol. transamidation is also described. A plausible reaction mechanistic pathway involving H-bonding is discussed. The graphene oxide can be recycled and reused up to five cycles without much loss in catalytic activity. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7HPLC of Formula: 2387-23-7).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.HPLC of Formula: 2387-23-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics