Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 97308-23-1, name is tert-Butyl aziridine-1-carboxylate, A new synthetic method of this compound is introduced below., Product Details of 97308-23-1
Step 4 To the solution tert-butyl aziridine-1-carboxylate LXXXVI (excess) in dioxane was added (2-aminioethyl)trimethylazanium dichloride LXXXIV (0.25 g; 1.8 mmol). The mixture was refluxed for 3 days. The solvent was removed under reduced pressure and the residue was purified on a silica gel column (100:1 CHCl3:MeOH) to give crude tert-butyl N-(2-{[2-(trimethylaminio)ethyl]amino}ethyl)carbamate chloride LXXXVII was used directly for step 5.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Mpex Pharmaceuticals, Inc.; US2008/318957; (2008); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics