Category: 89-73-6

Li, Zhenbiao;Wei, Yingying;Cao, Zidan;Jiang, Shu;Chen, Yi;Shao, Xingfeng published 《The Jasmonic Acid Signaling Pathway is Associated with Terpinen-4-ol-Induced Disease Resistance against Botrytis cinerea in Strawberry Fruit》 in 2021. The article was appeared in 《Journal of Agricultural and Food Chemistry》. They have made some progress in their research.Recommanded Product: 89-73-6 The article mentions the following:

Terpinen-4-ol, the main component of tea tree oil, markedly increases the disease resistance of postharvest strawberry fruit. To understand the mechanism underlying the enhancement of disease resistance, a high-throughput RNA-seq was used to analyze gene transcription in terpinen-4-ol-treated and untreated fruit. The results show that terpinen-4-ol induces the expression of genes in the jasmonic acid (JA) biosynthesis pathway, secondary metabolic pathways such as phenylpropanoid biosynthesis, and pathways involved in plant-pathogen interactions. Terpinen-4-ol treatment reduced disease incidence and lesion diameter in strawberry fruit inoculated with Botrytis cinerea. Terpinen-4-ol treatment enhanced the expression of genes involved in JA synthesis (FaLOX, FaAOC, and FaOPR3) and signaling (FaCOI1), as well as genes related to disease defense (FaPAL, FaCHI, and FaGLU). In contrast, treatment with the JA biosynthesis inhibitor salicylhydroxamic acid (SHAM) accelerated disease development and inhibited the induction of gene expressions by terpinen-4-ol. We conclude that the JA pathway participates in the induction of disease resistance by terpinen-4-ol in strawberry fruit. More generally, the results illuminate the mechanisms by which disease resistance is enhanced by essential oils. And N,2-Dihydroxybenzamide (cas: 89-73-6) was used in the research process.

N,2-Dihydroxybenzamide(cas: 89-73-6) is a hydroxamic acid that inhibits the activity of p-hydroxybenzoic acid (PHBA) reductase, an enzyme involved in the conversion of PHBA to benzoic acid. Recommanded Product: 89-73-6 The compound has been shown to inhibit mitochondrial membrane potential and mitochondrial functions, leading to cell death.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Vega de Luna, Felix;Cordoba-Granados, Juan Jose;Dang, Kieu-Van;Roberty, Stephane;Cardol, Pierre published 《In vivo assessment of mitochondrial respiratory alternative oxidase activity and cyclic electron flow around photosystem I on small coral fragments》 in 2020. The article was appeared in 《Scientific Reports》. They have made some progress in their research.Name: N,2-Dihydroxybenzamide The article mentions the following:

The mutualistic relationship existing between scleractinian corals and their photosynthetic endosymbionts involves a complex integration of the metabolic pathways within the holobiont. Respiration and photosynthesis are the most important of these processes and although they have been extensively studied, our understanding of their interactions and regulatory mechanisms is still limited. In this work we performed chlorophyll-a fluorescence, oxygen exchange and time-resolved absorption spectroscopy measurements on small and thin fragments (0.3 cm2) of the coral Stylophora pistillata. We showed that the capacity of mitochondrial alternative oxidase accounted for ca. 25% of total coral respiration, and that the high-light dependent oxygen uptake, commonly present in isolated Symbiodiniaceae, was negligible. The ratio between photosystem I (PSI) and photosystem II (PSII) active centers as well as their resp. electron transport rates, indicated that PSI cyclic electron flow occurred in high light in S. pistillata and in some branching and lamellar coral species freshly collected in the field. Altogether, these results show the potential of applying advanced biophys. and spectroscopic methods on small coral fragments to understand the complex mechanisms of coral photosynthesis and respiration and their responses to environmental changes. The experimental procedure involved many compounds, such as N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) is widely used for a variety of roles in biology and medicine as a chelating therapy.Name: N,2-DihydroxybenzamideIt inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Mazorra Morales, Luis Miguel;Cosme Silva, Glaucia Michelle;Santana, Diederson Bortolini;Pireda, Saulo F.;Dorighetto Cogo, Antonio Jesus;Heringer, Angelo Schuabb;de Oliveira, Tadeu dos Reis;Reis, Ricardo S.;dos Santos Prado, Luis Alfredo;de Oliveira, Andre Vicente;Silveira, Vanildo;Da Cunha, Maura;Barros, Claudia F.;Facanha, Arnoldo R.;Baldet, Pierre;Bartoli, Carlos G.;da Silva, Marcelo Gomes;Oliveira, Jurandi G. published 《Mitochondrial dysfunction associated with ascorbate synthesis in plants》 in 2022. The article was appeared in 《Plant Physiology and Biochemistry (Issy-les-Moulineaux, France)》. They have made some progress in their research.Product Details of 89-73-6 The article mentions the following:

Mitochondria are the major organelles of energy production; however, active mitochondria can decline their energetic role and show a dysfunctional status. Mitochondrial dysfunction was induced by high non-physiol. level of L-galactone-1,4-lactone (L-GalL), the precursor of ascorbate (AsA), in plant mitochondria. The dysfunction induced by L-GalL was associated with the fault in the mitochondrial electron partition and reactive oxygen species (ROS) over-production Using mitochondria from RNAi-plant lines harbouring silenced L-galactone-1,4-lactone dehydrogenase (L-GalLDH) activity, it was demonstrated that such dysfunction is dependent on this enzyme activity. The capacity of alternative respiration was strongly decreased by L-GalL, probably mediated by redox-inactivation of the alternative oxidase (AOX) enzyme. Although, alternative respiration was shown to be the key factor that helps support AsA synthesis in dysfunctional mitochondria. Experiments with respiratory inhibitors showed that ROS formation and mitochondrial dysfunction were more associated with the decline in the activities of COX (cytochrome oxidase) and particularly AOX than with the lower activities of respiratory complexes I and III. The application of high L-GalL concentrations induced proteomic changes that indicated alterations in proteins related to oxidative stress and energetic status. However, supra-optimal L-GalL concentration was not deleterious for plants. Instead, the L-GalLDH activity could be pos. Indeed, it was found that wild type plants performed better growth than L-GalLDH-RNAi plants in response to high non-physiol. L-GalL concentrations The experimental procedure involved many compounds, such as N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) has also been shown to be active against wild-type strains of Candida glabrata, but not against resistant mutants. Product Details of 89-73-6 This drug may have therapeutic potential for bone cancer and metabolic disorders such as obesity.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Application of 89-73-6In 2021, Chen, Tomer;Cohen, Dekel;Itkin, Maxim;Malitsky, Sergey;Fluhr, Robert published 《Lipoxygenase functions in ¹O₂ production during root responses to osmotic stress》. 《Plant Physiology》published the findings. The article contains the following contents:

Drought induces osmotic stress in roots, a condition simulated by the application of high-mol.-weight polyethylene glycol. Osmotic stress results in the reduction of Arabidopsis thaliana root growth and production of 1O2 from an unknown non-photosynthetic source. Reduced root growth can be alleviated by application of the 1O2 scavenger histidine (HIS). Here, we examined the possibility that 1O2 production involves Russell reactions occurring among the enzymic products of lipoxygenases (LOXs), the fatty acid hydroperoxides. LOX activity was measured for purified soybean (Glycine max) LOX1 and in crude Arabidopsis root extracts using linoleic acid as substrate. Formation of the 13(S)-Hydroperoxy-9(Z),11(E)-octadecadienoic acid product was inhibited by salicylhdroxamic acid, which is a LOX inhibitor, but not by HIS, whereas 1O2 production was inhibited by both. D2O, which specifically extends the half-life of 1O2, augmented the LOX-dependent generation of 1O2, as expected from a Russell-type reaction. The addition of linoleic acid to roots stimulated 1O2 production and inhibited growth, suggesting that the availability of LOX substrate is a rate-limiting step. Indeed, water stress rapidly increased linoleic and linolenic acids by 2.5-fold in roots. Mutants with root-specific microRNA repression of LOXs showed downregulation of LOX protein and activity. The lines with downregulated LOX displayed significantly less 1O2 formation, improved root growth in osmotic stress, and an altered transcriptome response compared with wild type. The results show that LOXs can serve as an enzymic source of dark 1O2 during osmotic stress and demonstrate a role for 1O2 in defining the physiol. response. To complete the study, the researchers used N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) can be used:To prepare phenylboronic acid-based bioconjugates for chromatographic applications;As a ligand to synthesize Fe(III), Cu(II), Ni(II) and Zn(II) complexes.Application of 89-73-6

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Recommanded Product: N,2-DihydroxybenzamideIn 2020, Salerno, Elvin V.;Eliseeva, Svetlana V.;Schneider, Bernadette L.;Kampf, Jeff W.;Petoud, Stephane;Pecoraro, Vincent L. published 《Visible, Near-Infrared, and Dual-Range Luminescence Spanning the 4f Series Sensitized by a Gallium(III)/Lanthanide(III) Metallacrown Structure》. 《Journal of Physical Chemistry A》published the findings. The article contains the following contents:

Ga³⁺/Ln³⁺ metallacrowns (MCs) [LnGa₈(shi)₈(OH)₄]Na·xMeOH·yH₂O (Ln-1, Ln = Pr³⁺, Nd³⁺, Sm³⁺-Yb³⁺ and analog Y³⁺; H₃shi = salicylhydroxamic acid) is presented. Ln-1 were obtained by reacting Ga³⁺ and Ln³⁺ nitrate salts with the H₃shi ligand. X-ray single crystal unit cell anal. confirmed that all MCs are isostructural. The crystal structure was solved for the Nd³⁺ analog and revealed that Nd³⁺ is centered between 2 [12-MC_Ga^III_N(shi)-4] MC rings and bound to 8 hydroximate O ions (4 from each ring) in a pseudosquare antiprismatic fashion adopting a pseudo-D_4h symmetry. Pulsed gradient spin echo diffusion ordered ¹H NMR spectroscopy and electrospray ionization mass spectrometry confirmed that the structure of Ln-1 remains intact in MeOH solutions while mass spectrometry suggests that 4 OH^– bridges are exchanged with MeO^–/CD₃O^–. An exceptional ability of this series of MCs to sensitize the characteristic emission of Ln³⁺ was confirmed with the observation of bright red and green emission signals of Eu-1 and Tb-1, NIR emissions of Yb-1 and Nd-1, and dual-range emissions of Pr-1, Sm-1, Dy-1, Ho-1, Er-1, and Tm-1 in the solid state upon excitation into ligand-centered bands at 340 nm. The luminescence properties of Ln-1 (Ln = Nd³⁺, Sm³⁺, Eu³⁺, Tb³⁺, Dy³⁺, and Yb³⁺) were also studied in MeOH and CD₃OD solutions For Eu-1 and Yb-1 MCs, more extensive analyses of the photophys. properties were performed, which included the determination of radiative lifetimes, intrinsic quantum yields, and sensitization efficiencies. The absolute quantum yields (Q_Ln^L) of Ln-1 in the visible and NIR ranges were determined In the case of Sm-1, the values of Q_Ln^L in MeOH and CD₃OD solutions are exceptionally high, i.e., 10.1(5) and 83(1)%. Values obtained for Yb-1, i.e., 0.78(4)% in MeOH and 8.4(1)% in CD₃OD, are among the highest ones reported today for Yb³⁺ complexes formed with nondeuterated and nonhalogenated ligands. The experimental procedure involved many compounds, such as N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) can be used:To prepare phenylboronic acid-based bioconjugates for chromatographic applications;As a ligand to synthesize Fe(III), Cu(II), Ni(II) and Zn(II) complexes.Recommanded Product: N,2-Dihydroxybenzamide

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Liu, Ying;Zhang, Hua;Cui, Yan;Zheng, Yanli;Chen, Hui;Hu, Zhangli;Wu, Qingyu published 《Distinct roles of alternative oxidase pathway during the greening process of etiolated algae》 in 2021. The article was appeared in 《Science China: Life Sciences》. They have made some progress in their research.Safety of N,2-Dihydroxybenzamide The article mentions the following:

The vital function of mitochondrial alternative oxidase (AOX) pathway in optimizing photosynthesis during plant de-etiolation has been well recognized. However, whether and how AOX impacts the chloroplast biogenesis in algal cells remains unclear. In the present study, the role of AOX in regulating the reassembly of chloroplast in algal cells was investigated by treating Auxenochlorella protothecoides with salicylhydroxamic acid (SHAM), the specific inhibitor to AOX, in the heterotrophy to autotrophy transition process. Several lines of evidences including delayed chlorophyll accumulation, lagged reorganization of chloroplast structure, altered PSI/PSII stoichiometry, and declined photosynthetic activities in SHAM treated cells indicated that the impairment in AOX activity dramatically hindered the development of functioning chloroplast in algal cells. Besides, the cellular ROS levels and antioxidant enzymes activities were increased by SHAM treatment, and the perturbation on the balance of NAD⁺/NADH and NADP⁺/NADPH ratios was also observed in A. protothecoides lacking AOX activity, indicating that AOX was essential in promoting ROS scavenging and keeping the redox homeostasis for algal chloroplast development during greening. Our study revealed the essentiality of mitochondrial AOX pathway in sustaining algal photosynthetic performance and provided novel insights into the physiol. roles of AOX on the biogenesis of photosynthetic organelle in algae.N,2-Dihydroxybenzamide (cas: 89-73-6) were involved in the experimental procedure.

N,2-Dihydroxybenzamide(cas: 89-73-6) has also been shown to be active against wild-type strains of Candida glabrata, but not against resistant mutants. Safety of N,2-Dihydroxybenzamide This drug may have therapeutic potential for bone cancer and metabolic disorders such as obesity.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Miao, Yongchao;Wen, Shuming;Feng, Qicheng;Liao, Runpeng published 《Enhanced adsorption of salicylhydroxamic acid on ilmenite surfaces modified by Fenton and its effect on floatability》 in 2021. The article was appeared in 《Colloids and Surfaces, A: Physicochemical and Engineering Aspects》. They have made some progress in their research.Name: N,2-Dihydroxybenzamide The article mentions the following:

This work reports a new method of using Fenton to oxidize and modify the ilmenite surface using salicylhydroxamic acid (SHA) as the collector. The activation mechanism of this process was studied by analyzing changes that occurred on the ilmenite surface. Micro-flotation showed that the maximum recovery of ilmenite after treatment with Fenton increased by 37% and attributed to the increase in the adsorbed SHA amount on the ilmenite surface. Zeta potential and XPS measurement data showed that Fenton promoted the conversion of Fe2+→Fe3+ on the ilmenite surface that enhanced SHA adsorption. After adding Fenton, the Fe-SHA complex (formed in the pulp) interacted with the O sites of ilmenite surfaces, and improved the ilmenite floatability. The IR spectra of the ilmenite+Fenton+SHA system showed several intense bands that indicated enhanced SHA chemisorption on the ilmenite surface. Thus, ilmenite treatment with the Fenton promoted its surface reactivity caused SHA to bind with the ilmenite surface and enhanced the ilmenite floatability.N,2-Dihydroxybenzamide (cas: 89-73-6) were involved in the experimental procedure.

N,2-Dihydroxybenzamide(cas: 89-73-6) is widely used for a variety of roles in biology and medicine as a chelating therapy.Name: N,2-DihydroxybenzamideIt inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Rauguth, Andreas;Kredel, Alexander;Carrella, Luca M.;Rentschler, Eva published 《3d/4f Sandwich Complex Based on Metallacrowns》. The research results were published in《Inorganic Chemistry》 in 2021.COA of Formula: C7H7NO3 The article conveys some information:

A novel lanthanide double-decker complex with nickel metallacrowns (MCs) as coordinating ligands has been synthesized. In the 3d/4f metallacrown complex Tb^III[12-MC_Ni^IIN(shi)-4]₂, the central lanthanide ion is sandwiched between two [12-MC-4] units, forming an almost ideal square-antiprismatic coordination sphere. The resulting zenithal angles at the central lanthanide ion are smaller than those for previously reported sandwich compounds Magnetic measurements reveal an energy barrier of 346 K under zero field and up to 585 K under 3200 Oe, the highest reported for metallacrowns with D_4d symmetry. And N,2-Dihydroxybenzamide (cas: 89-73-6) was used in the research process.

N,2-Dihydroxybenzamide(cas: 89-73-6) is a hydroxamic acid that inhibits the activity of p-hydroxybenzoic acid (PHBA) reductase, an enzyme involved in the conversion of PHBA to benzoic acid. COA of Formula: C7H7NO3 The compound has been shown to inhibit mitochondrial membrane potential and mitochondrial functions, leading to cell death.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Luo, Yin;Tang, Haishuang;Zhang, Zhaolong;Zhao, Rui;Wang, Chuanchuan;Hou, Wenguang;Huang, Qinghai;Liu, Jianmin published 《Pharmacological inhibition of epidermal growth factor receptor attenuates intracranial aneurysm formation by modulating the phenotype of vascular smooth muscle cells》 in 2022. The article was appeared in 《CNS Neuroscience & Therapeutics》. They have made some progress in their research.Name: N,2-Dihydroxybenzamide The article mentions the following:

To study the effect of pharmacol. inhibition of epidermal growth factor receptor (EGFR) on intracranial aneurysm (IA) initiation. Human IA samples were analyzed for the expression of p-EGFR and alpha smooth muscle actin (α-SMA) by immunofluorescence (IF). Rat models of IA were established to evaluate the ability of the EGFR inhibitor, erlotinib, to attenuate the incidence of IA. We analyzed anterior cerebral artery tissues by pathol. and proteomic detection for the expression of p-EGFR and relevant proteins, and vessel casting was used to evaluate the incidence of aneurysms in each group. Rat vascular smooth muscle cells (VSMCs) and endothelial cells were extracted and used to establish an in vitro co-culture model in a flow chamber with or without erlotinib treatment. We determined p-EGFR and relevant protein expression in VSMCs by immunoblotting anal. Epidermal growth factor receptor activation was found in human IA vessel walls and rat anterior cerebral artery walls. Treatment with erlotinib markedly attenuated the incidence of IA by inhibiting vascular remodeling and pro-inflammatory transformation of VSMC in rat IA vessel walls. Activation of EGFR in rat VSMCs and phenotypic modulation of rat VSMCs were correlated with the strength of shear stress in vitro, and treatment with erlotinib reduced phenotypic modulation of rat VSMCs. In vitro experiments also revealed that EGFR activation could be induced by TNF-α in human brain VSMCs. These results suggest that EGFR plays a critical role in the initiation of IA and that the EGFR inhibitor erlotinib protects rats from IA initiation by regulating phenotypic modulation of VSMCs. The experimental procedure involved many compounds, such as N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) can be used:To prepare phenylboronic acid-based bioconjugates for chromatographic applications;As a ligand to synthesize Fe(III), Cu(II), Ni(II) and Zn(II) complexes.Name: N,2-Dihydroxybenzamide

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

SDS of cas: 89-73-6《Significance of dimeric surfactant on kinetic study of organophosphorus compounds》 was published in 2022. The authors were Lakra, Jyotsna;Tikariha, Deepti;Kumar, Birendra, and the article was included in《International Journal of Chemical Kinetics》. The author mentioned the following in the article:

Dimeric surfactants have shown significant role on hydrolysis of organo-phosphorus compounds In this study, we have studied the kinetic hydrolysis of p-nitrophenyl acetate (PNPA), p-nitrophenyl benzoate (PNPB), and p-dinitrophenyl di-Ph phosphate (PNPDPP) in presence of novel dimeric surfactants 12-4-12, 2Br- (butanediyl-1,4-bis(dimethyldodecylammonium bromide)), 12-4(OH)-12, 2Br- (2-butanol-1,4-bis(dimethyldodecylammonium bromide)) with conventional nucleophiles, benzohydroxamic acid (BHA), and salicylhydroxamic acid (SHA) by spectrophotometry at 27°C. Kinetic study on effect of micelles on reaction rates have been investigated and rationalization effects of micelles determination using kinetic model. The exptl. kinetic data were fitted with micellar pseudophase model for determination micellar substrate binding and parameters. The second order rate constant is processed for comparing the reactivities in aqueous and micellar pseudophase. And N,2-Dihydroxybenzamide (cas: 89-73-6) was used in the research process.

N,2-Dihydroxybenzamide(cas: 89-73-6) is a hydroxamic acid that inhibits the activity of p-hydroxybenzoic acid (PHBA) reductase, an enzyme involved in the conversion of PHBA to benzoic acid. SDS of cas: 89-73-6 The compound has been shown to inhibit mitochondrial membrane potential and mitochondrial functions, leading to cell death.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics