In 2019,ChemistrySelect included an article by Porala, Subbanarasimhulu; Yerrabelly, Jayaprakash Rao; Kasireddy, Venkateshwar Reddy; Yerrabelly, Hemasri; Ghojala, Venkat Reddy; Rebelli, Pradeep. Synthetic Route of C9H19ClN2O2. The article was titled 《New and efficient synthesis of HCV NS3/4 A protease inhibitor Telaprevir》. The information in the text is summarized as follows:
An efficient and improved approach for the synthesis of HCV NS3/4 A (Hepatitis C virus Non-structural protein 3) protease inhibitor, Telaprevir has been developed, which involves the novel synthesis of key intermediates β-amino-α-hydroxy amide (I) and tripeptide acid (II). The synthesis of β-amino-α-hydroxy amide I was designed via the monochloro and dichloro intermediates using the crossed Claisen condensation followed by decarboxylation with good overall yield (29.62%). The tripeptide acid II was developed by the coupling of dipeptide acid with bicyclic nitrile followed by simple chem. conversions in less number of steps with good overall yield (61.2%). After reading the article, we found that the author used (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride(cas: 850252-34-5Synthetic Route of C9H19ClN2O2)
amides-buliding-blocks(cas:850252-34-5) is one of amino acids. Amino acids are organic compounds that contain both amino and carboxylic acid functional groups Although hundreds of amino acids exist in nature, by far the most prevalent are the alpha-amino acids, which comprise proteins.Synthetic Route of C9H19ClN2O2 Only 22 alpha amino acids appear in the genetic code.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics