Nguyen, Vu Thanh published the artcileOne-pot three-component synthesis of 1-amidoalkyl naphthols and polyhydroquinolines using a deep eutectic solvent: A green method and mechanistic insight, Name: 2-Chloroacetamide, the publication is New Journal of Chemistry (2021), 45(4), 2053-2059, database is CAplus.
The multicomponent synthesis of 1-amidoalkyl naphthols I [R1 = n-Pr, Ph, 4-MeC6H4, 2-furyl, etc., R2 = Ph, CH2Cl] and polyhydroquinolines II [R = furan-2-yl, Ph, 2-ClC6H4, etc.] was developed as an atom-economic procedure catalyzed by a deep eutectic solvent ([CholineCl][ZnCl2]3). The reactions proceeded smoothly at low temperatures for a short reaction time without the use of toxic and volatile organic solvents. Deep eutectic solvents were capable of not only allowing multicomponent reactions to proceed in high yield but also controlling the selectivity towards desired products. Mechanistic insights were examined by HRMS (ESI) to propose a plausible mechanism. Furthermore, [CholineCl][ZnCl2]3 could be recycled up to three consecutive cycles with an insignificant loss of catalytic activity under the optimized conditions.
New Journal of Chemistry published new progress about 79-07-2. 79-07-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Aliphatic hydrocarbon chain,Amide,Inhibitor, name is 2-Chloroacetamide, and the molecular formula is C2H4ClNO, Name: 2-Chloroacetamide.
Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics