Category: 7465-88-5

Tian, Chao published the artcileVisible-Light Mediated ortho-Trifluoromethylation of Aniline Derivatives, Computed Properties of 7465-88-5, the main research area is visible light regioselective ortho trifluoromethylation aniline Langlois reagent photocatalyst.

A general visible-light mediated ortho-C-H trifluoromethylation of aniline derivatives by using a low-cost and stable Langlois reagent (CF3SO2Na) as the “”CF3″” source has been developed. In contrast to previous reports, this strategy allowed access to elusive trifluoromethyl lactams. Furthermore, mechanism experiments revealed that a copper/photoredox dual catalytic mechanism enabled general trifluoromethylation of aniline derivatives

Journal of Organic Chemistry published new progress about Photocatalysts. 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Computed Properties of 7465-88-5.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Tang, Yanling published the artcileEfficient Pd-Catalyzed Hydrodehalogenation of o-Haloanilides in Water, Recommanded Product: 4-Methoxy-N-phenylbenzamide, the main research area is anilide green preparation; haloanilide regioselective hydrodehalogenation palladium catalyst.

A practical methodol. for the synthesis of anilides RC(O)NHPh [R = Me, Bn, 4-FC6H4, etc.] via hydrodehalogenation of o-haloanilides using PdCl2 at 100°C under mild conditions in water was developed. The catalytic system could selectively dehalogenate both aryl chloride and aryl bromide and exhibit a broad functional group tolerance.

Synlett published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Recommanded Product: 4-Methoxy-N-phenylbenzamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yi, Xuewen published the artcileCopper-Catalyzed Radical N-Demethylation of Amides Using N-Fluorobenzenesulfonimide as an Oxidant, Related Products of amides-buliding-blocks, the main research area is copper catalyzed radical demethylation amide fluorobenzenesulfonimide.

An unprecedented N-demethylation of N-Me amides has been developed by use of N-fluorobenzenesulfonimide as an oxidant with the aid of a copper catalyst. The conversion of amides to carbinolamines involves successive single-electron transfer, hydrogen-atom transfer, and hydrolysis, and is accompanied by formation of N-(phenylsulfonyl)benzenesulfonamide. Carbinolamines spontaneously decompose to N-demethylated amides and formaldehyde, because of their inherent instability.

Organic Letters published new progress about Amines Role: SPN (Synthetic Preparation), PREP (Preparation) (carbinol). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Related Products of amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Du, Jinze published the artcileElectrochemical Oxidative ortho-Selective Trifluoromethylation of N-Arylamides, SDS of cas: 7465-88-5, the main research area is trifluoromethyl arylamide preparation regioselective; arylamide sodium trifluoromethanesulfinate electrochem oxidative trifluoromethylation.

A metal-catalyst-free and external-oxidant-free electrochem. oxidative radical C-H ortho-trifluoromethylation is presented. The reaction specifically occurred at the ortho-position of anilides RC(O)NHC6H4R1 (R = Ph, 2-furyl, 2-naphthyl, Me, etc., R1 = 3-Me, 4-Me, 4-Cl) without directing groups. Various anilides showed good tolerance to provide the desired products I in moderate to good yields. In addition, the gram-scale amplified product of benzanilide was obtained with a yield of 64%, which proved that it has a certain application potential.

ChemElectroChem published new progress about Electrochemical reaction (regioselective). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, SDS of cas: 7465-88-5.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Rahman, Mahbubur Md. published the artcileSynthesis of Sulfoxonium Ylides from Amides by Selective N-C(O) Activation, SDS of cas: 7465-88-5, the main research area is sulfoxonium ylide preparation; amide trimethylsulfoxonium iodide nitrogen carbon cleavage.

The direct synthesis of sulfoxonium ylides from amides by selective N-C(O) cleavage is presented. The reaction proceeds through the nucleophilic addition of dimethylsulfoxonium methylide to the amide bond in acyclic twisted amides under exceedingly mild room temperature conditions. A variety of amides can be employed, and the protocol can be applied to the late-stage derivatization of pharmaceuticals. Mechanistic studies outline the relative order of reactivity of amides.

Organic Letters published new progress about Bond cleavage (N-C(O)). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, SDS of cas: 7465-88-5.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yang, Dahyeon published the artcileNickel/briphos-catalyzed transamidation of unactivated tertiary amides, Recommanded Product: 4-Methoxy-N-phenylbenzamide, the main research area is tertiary amide transamidation primary amine nickel briphos catalyst.

The transamidation of tertiary amides was achieved via nickel catalysis in combination with briphos ligands. N-Methyl-N-phenylbenzamide derivatives reacted with primary amines in the presence of NiCl2/briphos ligand to provide the transamidated products in moderate to good yields. Primary aromatic amines delivered higher product yields than aliphatic amines.

Organic & Biomolecular Chemistry published new progress about Amides, tertiary Role: RCT (Reactant), RACT (Reactant or Reagent). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Recommanded Product: 4-Methoxy-N-phenylbenzamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zou, Long published the artcileVisible-light-induced Pd-catalyzed ortho-trifluoromethylation of acetanilides with CF3SO2Na under ambient conditions in the absence of an external photocatalyst, Formula: C14H13NO2, the main research area is regioselective trifluoromethylation acetaniline photocatalysis.

A visible-light-induced Pd-catalyzed ortho-trifluoromethylation of acetanilides with CF3SO2Na was developed. The reaction proceeded smoothly at room temperature in air without any external photocatalyst or additive, providing the desired products in moderate to good yields with good functional group tolerance and regioselectivity.

Chemical Communications (Cambridge, United Kingdom) published new progress about Optimization. 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Formula: C14H13NO2.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Xu, Ze-Ming published the artcileExogenous Photosensitizer-, Metal-, and Base-Free Visible-Light-Promoted C-H Thiolation via Reverse Hydrogen Atom Transfer, Safety of 4-Methoxy-N-phenylbenzamide, the main research area is benzothiazole preparation; photochem oxidative cyclization arylthioamide TEMPO catalyst; oxidative photochem intramol thiolation arylthioamide TEMPO catalyst; mechanism kinetics kinetic isotope effect photochem oxidative cyclization arylthioamide; reduction oxidation potential arylthioamide TEMPO.

N-Arylthioamides such as N-phenylthiobenzamide underwent photochem. visible-light oxidative cyclization reactions in the presence of TEMPO to yield benzothiazoles such as 2-phenylbenzothiazole without added photosensitizer, metal catalyst, or base. The mechanism of the reaction was studied by evaluation of the oxidation and reduction potentials of TEMPO and of selected reactants, determination of the kinetics of and kinetic isotope effects on the reaction, and mass spectrometric identification of reaction intermediates. The reaction likely occurs by absorption of visible light by thioamides to generate their excited states which undergo reverse hydrogen-atom transfer (RHAT) with 2,2,6,6-tetramethylpiperidine N-oxyl to form sulfur radicals; cyclization of the sulfur radicals onto the aryl ring followed by rearomatization via RHAT yields the benzothiazole products.

Organic Letters published new progress about Isotope effect. 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Safety of 4-Methoxy-N-phenylbenzamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics