Category: 713-41-7

Adding a certain compound to certain chemical reactions, such as: 713-41-7, name is 2-Amino-4-(trifluoromethyl)benzamide, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 713-41-7, Quality Control of 2-Amino-4-(trifluoromethyl)benzamide

Production Example 3 (1) 0753] A mixture of 1.0 g of 2-amino-4-trifluromethylbenzamide, 813 mg of 2-ethylsulfanylbenzaldehyde, 764 mg of sodium bisulfite and 4 ml of DMA was stirred at 150C for 8 hours. A saturated aqueous sodium bicarbonate solution and water were added to the cooled reaction mixture, and the precipitated solid was filtered. The resulting solid was washed with water and n-hexane and then dried to obtain 1.49 g of 2-(2-ethylsulfanylphenyl)-7-trifluoromethyl-3H-quinazolin-4 -one. 2-(2-Ethylsulfanylphenyl)-7-trifluoromethyl-3H-quinaz olin-4-one [0754] 1H-NMR(CDCl3)delta: 10.46(1H, brs), 8.43(1H, d), 8.11(1H, s), 7.91(1H, dd),7.72(1H, dd), 7.54 (1H, dd),7.50(1H, td), 7.41(1H, td), 2.92(2H, q), 1.28(3H, t).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-Amino-4-(trifluoromethyl)benzamide, and friends who are interested can also refer to it.

Reference:
Patent; SUMITOMO CHEMICAL COMPANY LIMITED; TAKAHASHI, Masaki; ITO, Mai; NOKURA, Yoshihiko; TANABE, Takamasa; SHIMIZU, Chie; EP2865671; (2015); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Related Products of 713-41-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 713-41-7, name is 2-Amino-4-(trifluoromethyl)benzamide belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

-(4-Chlorophenyl)-7-trifluoromethyl-3H-quinazolin To a stirred suspension of 2-amino-4-(trifluoromethyl)benzamide (33.6 g, 0.16 mol) in water (750 mL) was added dropwise 4-chlorobenzaldehyde. Iron trichloride hexahydrate (133 g) was then added in portions. The reaction mixture was then heated at reflux for 24 h. After allowing the suspension to cool to room tempera- ture, the precipitate was isolated by vacuum filtration washing with water (3 x 500 mL) and dried under vacuum (10 mbar, 50C). Yield = 50 g, 94%; HPLC-mass spectrometry (LC-MS): 3.7 min, 325 (M+).

The synthetic route of 2-Amino-4-(trifluoromethyl)benzamide has been constantly updated, and we look forward to future research findings.

Reference:
Patent; BASF SE; GROss, Steffen; POHLMAN, Matthias; NARINE, Arun; ROSENBAUM, Claudia; DESHMUKH, Prashant; DICKHAUT, Joachim; BANDUR, Nina Gertrud; KOeRBER, Karsten; KAISER, Florian; VON DEYN, Wolfgang; LANGEWALD, Juergen; CULBERTSON, Deborah L.; EBUENGA, Cecille; WO2011/36074; (2011); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics