Reference of 673-66-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 673-66-5, name is Azocan-2-one, This compound has unique chemical properties. The synthetic route is as follows.
Dimethyl sulfate (1.42 mL, 15 mmol) and 2-azacyclooctanone (1.91 g, 15 mmol) were added to a dried, argon flushed 2-necked round bottomed flask and the mixture was heated at 60 0C for 23 h. The mixture was then cooled to r.t. and added to a saturated aq. solution of Na2CO3 (100 mL). This solution was extracted with ether, dried over Na2SO4, filtrated and evaporated to give a brownish oil of the title compound (1.71 g, 81%). 1H NMR (CDCl3) delta: 3.62 (s, 3H); 3.44-3.40 (m, 2H); 2.34-2.30 (m, 2H); 1-71-1.65 (m, 2H); 1.64-1.58 (m, 2H); 1.50-1.44 (m, 2H); 1.42-1.35 (m, 2H).
The chemical industry reduces the impact on the environment during synthesis Azocan-2-one. I believe this compound will play a more active role in future production and life.
Reference:
Patent; ACADIA PHARMACEUTICALS INC.; WO2008/64136; (2008); A2;,
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