Synthetic Route of 67279-23-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 67279-23-6, name is 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione, This compound has unique chemical properties. The synthetic route is as follows.
Step 2: Preparation of 1,4-dichloro-5,6,7,8-tetrahydrophthalazine (compound 1c) The compound 1b (1 g, 6.02 mmol) was dissolved into phosphorus oxychloride (8 ml). The air in the system was replaced 3 times with nitrogen gas. The system was warmed up to a temperature of 110 C. and stirred for 3 h. The reaction was stopped and then naturally cooled. The reaction solution was slowly dripped into ice water. The mixture was adjusted to pH 10 with a 1N sodium hydroxide aqueous solution and extracted 3 times with ethyl acetate. Organic phases were combined, and the organic phase was washed with saturated brine and concentrated to dry, to obtain a compound 1c (1.1 g).
The chemical industry reduces the impact on the environment during synthesis 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Terns, Inc.; YU, Shanghai; LI, Ben; (28 pag.)US2020/190064; (2020); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics