Category: 5455-98-1

On September 30, 2021, Frick-Delaittre, Elena; Westhues, Stefan; Wolf, Aurel; Koopmans, Carsten; Koenig, Thomas; Guertler, Christoph; Laemmerhold, Kai; Thiel, Daniel; Movahhed, Sohajl published a patent.Electric Literature of 5455-98-1 The title of the patent was Method for the production of thermoplastic polyoxazolidinones. And the patent contained the following:

The invention relates to a process for producing thermoplastic polyoxazolidinones, comprising copolymerization of a diisocyanate compound (A) with a bisepoxide compound (B) in the presence of a catalyst (C) and a compound (D) optionally in a solvent (E); wherein the compound (D) is one or more compounds selected from the group consisting of monofunctional isocyanate, monofunctional epoxide, cyclic carbonate, monofunctional alc., monofunctional amine, preferred monofunctional epoxide; wherein the process is performed at reaction temperatures of ≥ 178 – ≤ 230°, preferred ≥ 182 – ≤ 220°, more preferred ≥ 188 – ≤ 210°; most preferred ≥ 190 – ≤ 205°; wherein the bisepoxide compound (B) comprises 2,4′-isopropylidenediphenol diglycidyl ether (2,4′ BADGE) and 4,4′-isopropylidenediphenol diglycidyl ether (4,4′ BADGE); and wherein the molar ratio of 2,4′-isopropylidenediphenol diglycidyl ether (2,4′ BADGE) is from >3 mol-% to <11 mol preferable >4 mol-% to <9 mol more preferable >5 mol-% to <8 mol related to the sum of 2,4'-isopropylidenediphenol diglycidyl ether (2,4' BADGE) and 4,4'-isopropylidenediphenol diglycidyl ether (4,4' BADGE). Thermoplastic polyoxazolidinone obtainable by the inventive process is also claimed. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Electric Literature of 5455-98-1

The Article related to thermoplastic polyoxazolidinone polymerization, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Electric Literature of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 29, 2021, Frick-Delaittre, Elena; Westhues, Stefan; Wolf, Aurel; Koopmans, Carsten; Koenig, Thomas; Guertler, Christoph; Laemmerhold, Kai; Thiel, Daniel; Movahhed, Sohajl published a patent.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione The title of the patent was Method for the production of thermoplastic polyoxazolidinones. And the patent contained the following:

The invention relates to a process for producing thermoplastic polyoxazolidinones, comprising copolymerization of a diisocyanate compound (A) with a bisepoxide compound (B) in the presence of a catalyst (C) and a compound (D) optionally in a solvent (E); wherein the compound (D) is one or more compounds selected from the group consisting of monofunctional isocyanate, monofunctional epoxide, cyclic carbonate, monofunctional alc., monofunctional amine, preferred monofunctional epoxide; wherein the process is performed at reaction temperatures of ≥ 178 – ≤ 230°, preferred ≥ 182 – ≤ 220°, more preferred ≥ 188 – ≤ 210°; most preferred ≥ 190 – ≤ 205°; wherein the bisepoxide compound (B) comprises 2,4′-isopropylidenediphenol diglycidyl ether (2,4′ BADGE) and 4,4′-isopropylidenediphenol diglycidyl ether (4,4′ BADGE); and wherein the molar ratio of 2,4′-isopropylidenediphenol diglycidyl ether (2,4′ BADGE) is from >3 mol-% to <11 mol preferable >4 mol-% to <9 mol more preferable >5 mol-% to <8 mol related to the sum of 2,4'-isopropylidenediphenol diglycidyl ether (2,4' BADGE) and 4,4'-isopropylidenediphenol diglycidyl ether (4,4' BADGE). Thermoplastic polyoxazolidinone obtainable by the inventive process is also claimed. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to thermoplastic polyoxazolidinone polymerization, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 7, 2020, Koopmans, Carsten; Laemmerhold, Kai; Guertler, Christoph; Frick-Delaittre, Elena; Wolf, Aurel; Simon, Joachim; Wang, Min; Thiel, Daniel; Leitner, Walter published a patent.HPLC of Formula: 5455-98-1 The title of the patent was Method for the production of thermoplastic polyoxazolidinone polymers. And the patent contained the following:

The invention relates to a process for producing thermoplastic polyoxazolidinones, comprising copolymerization of a diisocyanate compound (A) with a bisepoxide compound (B) in the presence of a catalyst (C) and a compound (D) in a solvent (E), characterized in that, the bisepoxide compound (B) comprises isosorbide diglycidyl ether, the catalyst (C) is selected from the group consisting of alkali halogenides and earth alkali halogenides, and transition metal halogenides, the compound (D) is selected from the group consisting of monofunctional isocyanate, monofunctional epoxide, and wherein the process comprises: (a) placing the solvent (E) and the catalyst (C) in a reactor to provide a mixture; and (b) adding the diisocyanate compound (A), the bisepoxide compound (B), and the compound (D) to the mixture resulting from step (a). Thermoplastic polyoxazolidinone obtainable by the inventive process is also claimed. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).HPLC of Formula: 5455-98-1

The Article related to thermoplastic polyoxazolidinone polymerization, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.HPLC of Formula: 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 1, 2020, Tong, Yutao; Cheng, Ruihua; Yu, Lingling; Liu, Boping published an article.Formula: C11H9NO3 The title of the article was New strategies for synthesis of amino-functionalized poly(propylene carbonate) over SalenCo(III)Cl catalyst. And the article contained the following:

New strategies for synthesis of amino-functionalized poly(propylene carbonate) (PPC) were applied by terpolymn. of carbon dioxide, propylene oxide, with (a) N-(2,3-epoxypropyl)-2-phthalimide (Monomer A)/N-(2-oxiranylmethyl)-1 or (b) N-(2-oxiranylmethyl)-1,1-dimethylethyl ester (Monomer B) over SalenCo(III)Cl/PPNCl catalysts system, followed by the removal of the resp. protecting groups. The SalenCo(III)Cl presented high activity and yielded the terpolymer with high polycarbonate selectivity, carbonate linkage content, as well as high head-to-tail stereoregularity (>99%). In terpolymn., the Monomer A contents in PPC-Pht were easily regulated up to 12.0 mol%. However, the protecting groups could not be completely removed because of the degradation of PPC-NH2-A during the deprotection process. Meanwhile, when terpolymn. with Monomer B, PPC-butoxy carbonyl was obtained varied the Monomer B contents from 1.3 to 4.5 mol%, and could be transformed completely into the amino-functionalized PPC-NH2-B without significant backbone degradation The contact angles of the functionalized PPC-NH2s prepared by two strategies showed the expected increase in hydrophilicity with the increasing content of amino entities. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Formula: C11H9NO3

The Article related to polypropylene carbonate amino functionalized salen catalyst, Plastics Manufacture and Processing: Formulating Procedures and Compositions and other aspects.Formula: C11H9NO3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 23, 2014, Qin, Bing; Li, Xin; Liang, Bo published a patent.Electric Literature of 5455-98-1 The title of the patent was Novel cyclic acetal, cyclic ketal diamines epoxy curing agents and degradable polymers and composites based thereon. And the patent contained the following:

The title curing agent can generate a degradable crosslinked polymer by performing polymerization reaction with an epoxy resin. The degradable crosslinked polymer can be degraded in a mixed system of acid and solvent under the condition of heating and stirring. This reinforced composite is prepared using the curing agent, the epoxy resin, and auxiliary materials. This reinforced composite can be degraded in a mixed system of acid and solvent under the condition of heating and stirring, and can be recovered and reutilized after neutralization. This reinforced composite has high mech. performance, and wide range of application. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Electric Literature of 5455-98-1

The Article related to degradable cyclic acetal ketal diamine crosslinking agent epoxy resin, Plastics Manufacture and Processing: Formulating Procedures and Compositions and other aspects.Electric Literature of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Rassou, Somasoudrame; Illy, Nicolas; Tezgel, Ozgul; Guegan, Philippe published an article in 2018, the title of the article was Anionic ring-opening polymerization of N-glycidylphthalimide: Combination of phosphazene base and activated monomer mechanism.Computed Properties of 5455-98-1 And the article contains the following content:

Anionic ring-opening polymerization of glycidyl phthalimide, initiated with alc.-phosphazene base systems and based on monomer activation with a Lewis acid (iBu3Al), has been studied. No propagation occurred for initiator: iBu3Al ratios less or equal to 1:3. For larger Lewis acid amounts, the first anionic ring-opening polymerizations of glycidyl phthalimide were observed Polymers were carefully characterized by NMR, MALDI-TOF mass spectrometry, and size exclusion chromatog. and particular attention was given to the detection of eventual transfer or side-reactions. However, polymer precipitation and transfer reaction to aluminum derivative were detrimental to monomer conversion, polymerization control, and limited polymer chain molar masses. The influence of reaction temperature and solvent on polymer precipitation and transfer reactions was studied and reaction conditions have been optimized leading to afford end-capped poly(glycidyl phthalimide) with narrow molar mass distributions. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Computed Properties of 5455-98-1

The Article related to anionic ringopening polymerization glycidylphthalimide phosphazene monomer mechanism, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Computed Properties of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 31, 2017, Lv, Jiang-bo; Ma, Jing-zhi; Cheng, Kang; Chen, Chang; Hu, Jiang-huai; Zeng, Ke; Yang, Gang published an article.Computed Properties of 5455-98-1 The title of the article was Insights into phthalonitrile/epoxy blends modification system from non-competitive cure system based on alicyclic anhydride. And the article contained the following:

A series of polymer blends were prepared from 1,3-bis(3,4-dicyanophenoxy)benzene (3BOCN) and epoxy resin with Me tetrahydrophthalic anhydride as curing agent. The curing behavior and curing kinetics of the blends were studied by differential scanning calorimetry. The apparent activation energy of the blends with various contents of 3BOCN was higher than that of the blends without 3BOCN. A model experiment suggested that there is no obvious reaction between phthalonitrile and epoxy. The thermal and mech. properties of the polymer blends were evaluated. The polymer blends exhibit high storage modulus and char yield compared with the neat epoxy. The polymer blends show ductile fracture morphol. by SEM images. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Computed Properties of 5455-98-1

The Article related to phthalonitrile oligomeric plasticizer alicyclic anhydride cured epoxy blend property, Plastics Manufacture and Processing: Formulating Procedures and Compositions and other aspects.Computed Properties of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 26, 2017, Peters, Edward Norman; Na, Ying; Ma, Shuailei; Yang, Jian published a patent.Electric Literature of 5455-98-1 The title of the patent was Method for production of cured epoxy material and composite core for aluminum conductor composite core reinforced cable. And the patent contained the following:

A method of forming a cured epoxy material comprises reacting a phenylene ether oligomer with an anhydride hardener to form a first product, adding an epoxy resin to the first product to form a second product, and curing the second product. The method provides an improved balance of heat resistance and toughness relative to corresponding methods in which the phenylene ether oligomer is pre-reacted with the epoxy resin prior to addition of hardener, and in which all components are mixed simultaneously. The cured epoxy material can be used in the composite core of an aluminum conductor composite core reinforced cable. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Electric Literature of 5455-98-1

The Article related to oligophenylene ether anhydride hardener prereaction epoxy resin curing, aluminum conductor epoxy resin composite core reinforced cable, Plastics Manufacture and Processing: Formulating Procedures and Compositions and other aspects.Electric Literature of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 19, 2014, Ahmed, Mahbub; Ashall-Kelly, Alexander; Gueritz, Louisa; McKenna, Jeffrey; McKenna, Joseph; Mutton, Simon; Parmar, Rakesh; Shepherd, Jon; Wright, Paul published a patent.Recommanded Product: 5455-98-1 The title of the patent was Azacycloalkanopyrrolopyrimidinedione derivatives as CFTR modulators and their preparation. And the patent contained the following:

The invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;a nd its therapeutic uses. The invention further provides a combination of pharmacol. active agents and a pharmaceutical composition Compounds of formula I wherein A is (CHR4)n; R1 is (un)substituted Ph, (un)substituted C4-7 cycloalkenyl and (un)substituted 5- to 6- membered heteroaryl; R2 is (un)substituted C1-6 alkyl, (un)substituted C3-7 cycloalkyl, (un)substituted C4-7 cycloalkenyl, etc.; R3 is Me and Et; when X is S, then Z is CHR4a and n is 1; when X is CHR4b, then Z is NR5 and N is 1 and 2; when Z is CHR4b, then Z is CHR4a and n is 0, 1 and 2; when X is C=CH2, CF2 and C(CH3)2, then Z is CHR4a and n is 0 and 1; R4 is H, C1-4 alkyl,C1-4 haloalkyl, Ph, etc.; R4a is H, C1-4 alkyl, C1-4 hydroxyalkyl, etc.; R4b is H and Me; R5 is H and C1-4 alkyl, etc.; and pharmaceutically acceptable salts thereof, are claimed. Example compound II was prepared by cyclization of 6-(2-mercaptoethyl)-1,3-dimethyl-5-phenyl-1,6-dihydropyrrolo[3,4-d]pyrimidine-2,4-dione with 5-methylfuran-2-carboxaldehyde. The invention compounds were evaluated for their CFTR modulatory activity (some data given). The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Recommanded Product: 5455-98-1

The Article related to azacycloalkanopyrrolopyrimidinedione preparation cftr modulator, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Recommanded Product: 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 19, 2014, Ahmed, Mahbub; Ashall-Kelly, Alexander; Bloomfield, Graham Charles; Gueritz, Louisa; McKenna, Jeffrey; McKenna, Joseph; Mutton, Simon; Parmar, Rakesh; Sheperd, Jon; Wright, Paul published a patent.Application In Synthesis of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione The title of the patent was Preparation of tricyclic compounds as CFTR channel inhibitors for treating polycystic kidney disease and diarrhea. And the patent contained the following:

The invention provides tricyclic compounds of general formula I or a pharmaceutical salt thereof, their use for inhibiting the CFTR channel, and methods of treating disease using same, particularly polycystic kidney disease and diarrhea. For I, R1 is Ph, (C4-C7)cycloalkenyl or a 5-6-membered heteroaryl ring, all optionally substituted; R2 is (C1-C6)alkyl, (C3-C7)cycloalkyl, (C4-C7)cycloalkenyl, etc., all optionally substituted; each R3 independently is Me or ethyl; R4 is hydrogen, (C1-C4)alkyl, halo(C1-C4)alkyl, etc.; R4′ is H or methyl; R4a is hydrogen, (C1-C4)alkyl, halo(C1-C4)alkyl, etc.; and X is O, NH, NMe, or -CH2-O- wherein the O atom is attached to the -C(R4)(R4′) atom of the ring. Pharmaceutical compositions containing I, alone or in combination with other active agents, are also disclosed. Synthetic procedures for preparing I are exemplified. Example compound (R)-II was prepared by reacting intermediate III with 5-methylfuran-2-carboxaldehyde and subjecting the racemate formed to chiral separation Using the Ion Works Quatro assay (R)-II had a CFTR IC50 of 1.58 μM. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Application In Synthesis of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to tricyclic compound preparation cftr channel inhibitor polycystic kidney disease, diarrhea treatment tricyclic compound cftr channel inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Application In Synthesis of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics