Adding a certain compound to certain chemical reactions, such as: 533-17-5, name is N-(2-chlorophenyl)acetamide, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 533-17-5, Formula: C8H8ClNO
General procedure: A mixture of N-phenylacetamide(2a, 135 mg, 1.0 mmol), iodine (254 mg, 1 mmol), TBHP (387 mg, 3.0 mmol, 70% in water) and toluene (2.0 mL) was added successively in a round-bottom flask, and the resulting soln. stirred for 24 h at 80 C. The mixture was then subjected to purification by preparative thin-layer chromatography (PE-EtOAc, 10:3) to afford product 3aa.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, N-(2-chlorophenyl)acetamide, other downstream synthetic routes, hurry up and to see.
Reference:
Conference Paper; Chen, Cui; Liu, Weibing; Zhou, Peng; Beilstein Journal of Organic Chemistry; vol. 12; (2016); p. 2250 – 2255;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics