Category: 530-40-5

Lieber, Charles M. published the artcileProbing polymer-induced reactivity effects in modified electrode/catalyst systems, Quality Control of 530-40-5, the publication is Journal of the Electrochemical Society (1986), 133(11), 442C-444C, database is CAplus.

To elucidate reactivity effects in modified electrode systems, the substitution kinetics of Ru(NH₃)₅(H₂O)²⁺ with substituted pyridines was selected: Ru(NH₃)₅(H₂O)²⁺ + R-Py → Ru(NH₃)₅(R-Py)²⁺ + H₂O; R-Py = pyridine derivatives: isonicotinamide, pyridine, 3-chloropyridine, or N,N-diethylisonicotinamide. A pyrolytic graphite electrode was modified with Nafion solutions to give in most cases a film thickness of ∼0.4 μm. Cyclic voltammograms were recorded and the kinetics and mechanistic implications were discussed. These results indicate that Nafion-modified electrodes may be utilized to effect chem. transformations that are quite different from those found in homogeneous solution

Journal of the Electrochemical Society published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Quality Control of 530-40-5.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Bald, Edward published the artcileThe synthetic utility of 2-halopyridinium salts. Preparation of pyridinemonocarboxylic esters and amides under mild conditions, Related Products of amides-buliding-blocks, the publication is Chemica Scripta (1979), 13(1), 47, database is CAplus.

The equimolar reaction of pyridinemonocarboxylic acids with alcs. or amines and 2-chloro-1-methylpyridinium iodide in the presence of 2 M amounts of Et₃N gave the corresponding pyridinemonocarboxylic esters or amides in good yields.

Chemica Scripta published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Related Products of amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Zhang, Jinqi published the artcileStudy on the aluminum amides conversion of esters to amides, Safety of N,N-Diethylisonicotinamide, the publication is Nanjing Daxue Xuebao, Ziran Kexue (1996), 32(2), 242-245, database is CAplus.

A convenient method was used for directly converting esters to amides by using the reagents derived from the reaction of trimethylaluminum with ammonium chloride, primary amines hydrochloride or secondary amines hydrochloride at high yield in relatively short reaction time and at low temperature Reactions of aluminum amides with aromatic esters were extensively studied and the influence of different substituting groups on the reaction was discussed. It was concluded that, if an electron-donating group was attached to the nitrogen atom instead of hydrogen, the reactivity of the aluminum amide would be increased, and, if an electron-withdrawing group was attached to benzene ring, the electron-deficiency of carboyl carbon would be increased, the yield of amides would be also increased.

Nanjing Daxue Xuebao, Ziran Kexue published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H11NO4, Safety of N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Wang, Shi-Meng published the artcileClickable coupling of carboxylic acids and amines at room temperature mediated by SO₂F₂: A significant breakthrough for the construction of amides and peptide linkages, Category: amides-buliding-blocks, the publication is Organic & Biomolecular Chemistry (2019), 17(16), 4087-4101, database is CAplus and MEDLINE.

A mild, simple, efficient and robust protocol was developed for the synthesis of amides RC(O)NR¹R² [R = Et, Ph, 2-furyl, 4-pyridyl, etc., R¹ = H, Et, Bn, etc., R² = Et, Ph, 3-pyridyl, etc.] via SO₂F₂-mediated clickable coupling of carboxylic acids with amines. Peptide linkages were also prepared using this methodol. The direct click reactions of acids and amines on gram scale were also demonstrated using an extremely easy work-up and purification process of washing with 1 M aqueous HCl to provide the desired amides in greater than 99% purity and excellent yields.

Organic & Biomolecular Chemistry published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C2H4ClNO, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Hu, Jingyan published the artcileAmidation Reaction of Quinoline-3-carboxylic Acids with Tetraalkylthiuram Disulfides under Simple Conditions: A facile Synthesis of Quinoline-3-carboxamides, SDS of cas: 530-40-5, the publication is Asian Journal of Organic Chemistry (2020), 9(12), 2191-2195, database is CAplus.

A highly efficient and simple procedure for the synthesis quinoline-3-carboxamides and their analogs via amidation reaction of quinoline-3-carboxylic acids with tetraalkylthiuram disulfides was developed. The reaction proceeded efficiently under simple reaction conditions and featured the generality of broad scope of substrates with good yields. This protocol provides a convenient procedure for the synthesis of various aza-heteroaromatic carboxamides, which is of pharmaceutical interest.

Asian Journal of Organic Chemistry published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, SDS of cas: 530-40-5.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Cheng, Chuanjie published the artcileA highly efficient Pd-C catalytic hydrogenation of pyridine nucleus under mild conditions, Recommanded Product: N,N-Diethylisonicotinamide, the publication is Tetrahedron (2009), 65(41), 8538-8541, database is CAplus.

A synergistic Pd-C catalytic hydrogenation of 4-pyridinecarboxamides straightforwardly to 4-piperidinecarboxamide hydrochlorides was developed in the presence of ClCH₂CHCl₂. It provided a novel strategy for highly efficient hydrogenation of pyridine nuclear by using low-cost Pd-C catalyst under mild conditions.

Tetrahedron published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Recommanded Product: N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Jiang, Biao-Lin published the artcileCobalt(II)/N,N’,N”-Trihydroxyisocyanuric Acid Catalyzed Aerobic Oxidative Esterification and Amidation of Aldehydes, Formula: C10H14N2O, the publication is Asian Journal of Organic Chemistry (2018), 7(5), 977-983, database is CAplus.

A protocol for a Co^II/N,N’,N”-trihydroxyisocyanuric acid (THICA)-catalyzed aerobic oxidative esterification and amidation of aldehydes has been developed. Preliminary insight into the mechanism indicates that such an oxidative C-O/N cross-coupling reaction proceeds by masking the aldehyde in a nucleophilic addition reaction with an alkoxy/amino source, thereby keeping the highly reactive formyl group from undesired oxidation This protocol for the oxidative esterification and amidation of aldehydes proceeds through two different pathways that are characterized by the intrinsic nucleophilicity of the alkanol and amine substrates. The former occurs in the presence of TsOH as a cocatalyst and orthoformates as the alkoxy sources, instead of alkanols, to efficiently afford the transient acetals. In contrast, the coupling of the more nucleophilic amines with aldehydes renders a readily accessible cross-coupling reaction that occurs without any cocatalyst but is limited by the potential inhibition of THICA upon nucleophilic substitution by an amine. Consequently, only sterically hindered amines were tolerated in this catalytic system, whereas further condensation occurred in the presence of primary amines to lead to imines.

Asian Journal of Organic Chemistry published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Formula: C10H14N2O.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Yam, Vivian Wing-Wah published the artcileSynthesis, photophysics, ion-binding studies, and structural characterization of organometallic rhenium(I) crown complexes, Recommanded Product: N,N-Diethylisonicotinamide, the publication is Organometallics (1995), 14(9), 4034-6, database is CAplus.

Re(I) complexes [Re(L)(CO)₃Cl] (1, L = I; 2, L = N-(2-pyridinylmethylene)phenylamine) and [Re(phen)(CO)₃(L’)]PF₆ (3, L’ = II; 4, L’ = 4-(N,N-diethylformamido)pyridine) were synthesized and their photophys. and cation binding properties studied. The x-ray crystal structure of 3 also was determined All the complexes exhibited long-lived intense yellow-green to orange-red emission upon visible light excitation both in the solid state and in fluid solutions at 298 K.

Organometallics published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C9H21NO3, Recommanded Product: N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Tian, Wan-Fa published the artcileVisible-Light Photoredox-Catalyzed Iminyl Radical Formation by N-H Cleavage with Hydrogen Release and Its Application in Synthesis of Isoquinolines, Category: amides-buliding-blocks, the publication is Organic Letters (2018), 20(5), 1421-1425, database is CAplus and MEDLINE.

An unprecedented visible-light photoredox-catalyzed iminyl radical formation by N-H cleavage with H₂ release has been developed. Its application in the synthesis of various isoquinolines, e.g., I, and related polyaromatics in high atom economy at ambient temperature by applying a photosensitizer, Acr⁺-Mes ClO₄^–, and a new cobalt catalyst, Co(dmgH)₂(4-CONMe₂Py)Cl is reported. Mechanistic investigations indicated that the generated iminyl radical initiates the cascade C-N/C-C bonds formation and the catalytic cycle occurs by a simultaneous oxidative as well as reductive quenching pathway.

Organic Letters published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C15H14O3, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Wang, Xinbo published the artcileAerobic oxidation of secondary benzylic alcohols and direct oxidative amidation of aryl aldehydes promoted by sodium hydride, Category: amides-buliding-blocks, the publication is Tetrahedron (2011), 67(19), 3406-3411, database is CAplus.

We reported herein new reactivities and possible mechanistic implications of a simplest oxidant (NaH/air) uncovered on a broad range of useful transformations, including aerobic alc. oxidations, allylic alc. isomerizations and oxidations, cyclopropyl alc. fragmentations, and direct aryl aldehyde oxidative amidations. These readily implementable transition-metal-free processes feature exceptional material accessibility, operational simplicity, and environmental compatibility, and add new dimensions to its synthetic utilities that are fairly robust yet had not previously been fully realized and systematically explored.

Tetrahedron published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C7H7ClN2S, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics