Category: 360-92-9

Bannwitz, Sven published the artcileSynthesis and Structure-Activity Relationships of Lapacho Analogues. 2. Modification of the Basic Naphtho[2,3-b]furan-4,9-dione, Redox Activation, and Suppression of Human Keratinocyte Hyperproliferation by 8-Hydroxynaphtho[2,3-b]thiophene-4,9-diones, Recommanded Product: N,N-Diethyl-2,2,2-trifluoroacetamide, the publication is Journal of Medicinal Chemistry (2014), 57(14), 6226-6239, database is CAplus and MEDLINE.

The basic structure of linearly anellated lapacho quinones, naphtho[2,3-b]furan-4,9-dione, was modified in the search for novel agents against keratinocyte hyperproliferation. The synthesis and structure-activity relationships of several heterocycle-fused naphthoquinones as well as a full range of 2- and 7-substituted derivatives of one of these, 8-hydroxynaphtho[2,3-b]thiophene-4,9-dione, are described. Out of a total of 71 analogs, particularly 2-thenoyl-substituted (I; R = 2-thienyl), 2-nicotinoyl-substituted (I; R = 3-pyridine), and 2-oxadiazole-substituted (I; R = Et) compared favorably with the antipsoriatic agent anthralin. Their potency for suppression of keratinocyte hyperproliferation, which was evaluated using HaCaT cells as a model, was combined with comparably low membrane-damaging effects toward keratinocytes, as established by the release of lactate dehydrogenase activity from the cytoplasm of the cells. With respect to the mechanism of action, redox activation of lapacho quinones by one- and two-electron reduction in isolated enzymic assays was studied, and their potential to generate superoxide was confirmed in the keratinocyte-based hyperproliferation assay.

Journal of Medicinal Chemistry published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Recommanded Product: N,N-Diethyl-2,2,2-trifluoroacetamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Mironov, V. F. published the artcileSynthesis and reactivity of halophosphoranes containing hexafluoroisopropyl substituents, Application of N,N-Diethyl-2,2,2-trifluoroacetamide, the publication is Zhurnal Organicheskoi Khimii (1994), 30(8), 1200-3, database is CAplus.

A symposium lecture with 21 references on preparation and reactions of [(CF₃)₂CHO]₄PCl. E.g., reaction of [(CF₃)₂CHO]₄PCl with (CF₃CO)₂O gave [(CF₃)₂CHO]₄PO₂CCF₃, which when treated with chloral gave [(CF₃)₂]₄POCH(CCl₃)O₂CCF₃. Treating [(CF₃)₂CHO]₄PCl with benzaldehyde, chloral, or acrolein gave, resp., [(CF₃)₂CHO]₄POCH(Cl)Ph, [(CF₃)₂CHO]₄POCH(Cl)CCl₃, or a mixture of [(CF₃)₂CHO]₄POCH(Cl)CH:CH₂ and E- and Z-[(CF₃)₂CHO]₄POCH:CHCH₂Cl.

Zhurnal Organicheskoi Khimii published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Application of N,N-Diethyl-2,2,2-trifluoroacetamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Yagupol’skii, Yu. L. published the artcileN-Substituted perfluoroalkyl thioamides and their derivatives, Quality Control of 360-92-9, the publication is Zhurnal Organicheskoi Khimii (1976), 12(10), 2213-17, database is CAplus.

RCONR1R2 (R = CF3, C3F7, C6F13; R1R2 = Et2, N-methylbenzothiazol-2-ylidene; R1 = H, R2 = Ph, benzothiazol-2-yl) reacted with P2S5 in pyridine to give the corresponding RCSNR1R2 (I) in 45-95% yield. Treating I with Cl gave RCCl2NR1R2 (R1 ≠ H) and RCCl:NR2. Treating I and PhNHCSPh with SF4 yielded RCF2NR1R2 and PhN:CFPh, resp.

Zhurnal Organicheskoi Khimii published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C20H21ClN4O4, Quality Control of 360-92-9.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Pierce, Arleen C. published the artcileAction of primary and secondary amines on trihalogenated esters, Application of N,N-Diethyl-2,2,2-trifluoroacetamide, the publication is Journal of Organic Chemistry (1963), 658-62, database is CAplus.

The reactions of a series of trichloro- and trifluoroacetates with primary and secondary amines were investigated at room temperature When the trichlorinated esters were treated with primary amines, acyl-oxygen cleavage occurred predominantly. A haloform-type cleavage took place when the same esters were treated with secondary amines. Trifluorinated esters were found to yield exclusively amides regardless of the amine used. In the trichloroacetate series the order of decreasing acyl-oxygen cleavage with BuNH₂ was found to be: PhO > CH₂:CHO > MeO equal or nearly equal to EtO > Me₃CO > PhCH₂O. When the same esters were treated with piperidine, the order of decreasing acyl-oxgyen cleavage was found to be: PhO > CH₂:CHO > CH₂:CHCH₂O equal or nearly equal to PhCH₂O > Me₃CO > MeO equal or nearly equal to EtO. Steric hindrance in both the ester and the amine influenced the type of cleavage that occurred. Solvents such as MeCN or dioxane increased the percent of haloform-type cleavage while CCl₄ induced exclusive acyl-oxygen cleavage. The infrared carbonyl stretching frequencies of all esters, amides, and carbamates prepared in this study were measured with a precision of ±2 cm^-1.

Journal of Organic Chemistry published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Application of N,N-Diethyl-2,2,2-trifluoroacetamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Pierce, Arleen C. published the artcileReactions of trihalogenated esters with triethylamine and anions, Recommanded Product: N,N-Diethyl-2,2,2-trifluoroacetamide, the publication is Journal of Organic Chemistry (1962), 3968-73, database is CAplus.

The reactions of several trihalogenated esters with triethylamine were studied at room temperature All the trihalogenated esters formed quaternary ammonium compounds with triethylamine. In the case of the trifluoro esters, the formation of N,N-diethyltrifluoroacetamide and an ether was a competing reaction. Amide formation was not observed for the tribromo and trichloro esters, at room temperature, but occurred with methyl thioltrichloroacetate. During this study it was observed that methyl trichloroacetate behaved as an alkylating agent toward sodium phenoxide, while ethyl trifluoroacetate behaved as an acylating agent. A significant feature of this work is the alkylating ability of alkyl trichloroacetates, at room temperature This property makes methyl trichloroacetate a potentially useful methylating agent to replace toxic compounds such as diazomethane or dimethyl sulfate.

Journal of Organic Chemistry published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Recommanded Product: N,N-Diethyl-2,2,2-trifluoroacetamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Luo, Zhongli published the artcileOne-Pot Synthesis of Tertiary Amides from Organic Trichlorides through Oxygen Atom Incorporation from Air by Convergent Paired Electrolysis, Computed Properties of 360-92-9, the publication is Journal of Organic Chemistry (2021), 86(8), 5983-5990, database is CAplus and MEDLINE.

A convergent paired electrolysis catalyzed by a B12 complex for the one-pot synthesis of a tertiary amide from organic trichlorides has been developed. Various readily available organic trichlorides, such as benzotrichloride and its derivatives, chloroform, dichlorodiphenyltrichloroethane (DDT), trichloro-2,2,2-trifluoroethane (CFC-113a), and trichloroacetonitrile (CNCCl₃), were converted to amides in the presence of tertiary amines through oxygen incorporation from air at room temperature The amide formation mechanism in the paired electrolysis, which was mediated by a cobalt complex, was proposed.

Journal of Organic Chemistry published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Computed Properties of 360-92-9.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Fritz, H. published the artcileStudies on organophosphorus compounds. XXVI. Synthesis and carbon-13 NMR spectra of N,N-dialkyl thioamides, Category: amides-buliding-blocks, the publication is Bulletin des Societes Chimiques Belges (1978), 87(7), 525-34, database is CAplus.

By a new sulfuration reagent, the dimer of p-methoxyphenylthionophosphine sulfide, a series of thioamides were prepared in almost quant. yields from the corresponding amides. Carbon-13 NMR spectra of tertiary thioamides of formic, acetic, trifluoroacetic, propionic, and butyric acids were completely assigned with the aid of extensive double resonance and shift reagent experiments and the data obtained were compared with those of the analogous amides. A linear relation between the carbon-13 chem. shifts of the C:S of ethylthioamides and C:O of the corresponding amide was found.

Bulletin des Societes Chimiques Belges published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Pailer, Matthias published the artcileDetermination of primary and secondary amines as amides by means of gas chromatography on packed and capillary columns, COA of Formula: C6H10F3NO, the publication is Monatshefte fuer Chemie (1966), 97(6), 1541-53, database is CAplus.

A very large number of phthalyl, succinyl, trifluoroacetyl, and pentafluoropropionyl derivatives of primary and secondary amines were prepared in order to investigate their suitability for gas-chromatog. separation, in studies on tobacco smoke amines. The best results were obtained with trifluoroacetyl derivatives (Makisumi and Saroff, CA 62, 13847b). Cooled 0.01 mole amine in 5 ml. absolute Et2O was treated with 0.01 mole (CF3CO)2O at -5°. The mixture was kept for 1 hr. and treated with 20 ml. Et2O (CH2Cl2 for difficultly soluble derivatives) and processed as usual to give 90-5% of the following F3CCONR1R2 (R1, R2, m.p., b.p./mm., and n20D given): Me, H, 48-49.5°, 80°/11, -; Et, H, -, 90°/11, 1.3600; Pr, H, -, 100°/11, 1.3718; iso-Pr, H, 52-3°, 60°/0.01, -; allyl, H, -, 100°/11, 1.3849; CH:CH2, H, -, 95°/11, 1.3932; MeO(CH2)3, H, -, 110°/11, 1.3900; Bu, H, -, 105°/11, 1.3803; EtMeCH, H, -, 95°/11, 1.3802; iso-Bu, H, -, 95°/11, 1.3792; tert-Bu, H, 44-5°, 70°/11, -; Am, H, -, 110°/11, 1.3901; PrMeCH, H, -, 45°/0.001, 1.3879; Et2CH, H, 52-3°, 105°/11, -; EtMeCHCH2, H, -, 115°/11, 1.3910; iso-Am, H, -, 115°/11, 1.3890; n-C6H13, H, -, 120°/11, 1.3969; n-C7H15, H, -, 135°/11, 1.4031; n-C8H17, H, -, 160°/11, 1.4089; EtBuCHCH2, H, -, 80°/0.001, 1.4117; n-C13H27, H, 62-3°, 100°/0.001, -; n-C15H31, H, 72-3°, 120°/0.001, -; n-C16H33, H, 69-70°, 140°/0.001, -; n-C18H37, H, 70-2°, 150°/0.001, -; 9-octadecenyl, H, -, 140°/0.001, -; cyclopentyl, H, 73°, 80°/0.001, -; cyclohexyl, H, 94-4.5°, 80°/0.001, -; cycloheptyl, H, 61-2°, 80°/0.001, -; MePhCH, H, -, 70°/0.001, -; PhCH2CH2, H, 55-6°, 70°/0.001, -; PhCH2, H, 73.5-4.5°, 70°/0.001, -; styryl, H, 105-7°, 110°/0.001, -; Me, Me, -, 50°/11, 1.3632; Me, Et, -, 60°/11, 1.3741; Et, Et, -, 65°/11, 1.3798; Pr, Pr, -, 85°/11, 1.3938; iso-Pr, iso-Pr, 52-3°, 85°/11, -; Pr, iso-Pr, -, 85°/11, 1.3929; allyl, allyl, -, 90°/11, 1.4124; Bu, Bu, -, 110°/11, 1.4045; sec-Bu, sec-Bu, -, 95°/11, 1.4072; iso-Bu, iso-Bu, -, 95°/11, 1.4031; iso-Bu, Bu, -, 100°/11, 1.4052; tert-Bu, iso-Pr, -, 80°/11, 1.4035; Am, Am, -, 120°/11, 1.4121; n-C8H17, Et, -, 150°/11, 1.4146; n-C8H17, n-C8H17, -, 130°/0.05, 1.4305; n-C18H37, Me, 31-3°, 160°/0.001, -; cyclohexyl, cyclohexyl, sublimes 210°, 120°/0.05, -; PhCH2, PhCH2, -, 125°/0.05, 1.5278; (R1R2N =) Δ3-pyrrolyl, -, 90°/11, 1.4195; (R1R2N =) pyrrolidinyl, -, 90°/11, 1.4082; (R1R2N =) 2-methylpyrrolidinyl, -, 100°/11, -; (R1R2N =) 3-methylpyrrolidinyl, -, 100°/11, 1.4094; (R1R2N =) 2-ethylpyrrolidinyl, -, 105°/11, 1.4141; (R1R2N =) 2-propylpyrrolidinyl, -, 110°/11, 1.4188; (R1R2N =) 2-phenylpyrrolidinyl, -, 115°/0.05, 1.4911; (R1R2N =) 2-pyrridylpyrrolidinyl, -, 125°/0.05, 1.4962; (R1R2N =) 2,3-dimethylpyrrolidinyl, -, 100°/11, 1.4129; (R1R2N =) 2,4-dimethylpyrrolidinyl, -, 95°/11, 1.4080; (R1R2N =) 2,5-dimethylpyrrolidinyl, -, 90°/11, 1.4116; (R1R2N =) 3,4-dimethylpyrrolidinyl, -, 130°/11, -; (R1R2N =) piperidino, -, 90°/11, 1.4170; (R1R2N =) 2-methylpiperidino, -, 105°/11, 1.4205; (R1R2N =) 3-methylpiperidino, -, 100°/11, 1.4175; (R1R2N =) 4-methylpiperidino, -, 105°/11, 1.4181; (R1R2N =) 2-ethylpiperidino, -, 110°/11, 1.4246; (R1R2N =) 2,3-dimethylpiperidino, -, 115°/11, 1.4246; (R1R2N =) 2,4-dimethylpiperidino, -, 110°/11, 1.4201; (R1R2N =) 2,6-dimethylpiperidino, -, 110°/11, 1.4262; (R1R2N =) morpholino, -, 115°/11, 1.4182; Ph, H, 89-90°, 50°/0.001, -; 2-MeC6H4, H, 78-9°, 60°/0.001, -; 3-MeC6H4, H, 64.5-5.5°, 70°/0.001, -; 4-MeC6H4, H, 111°, 70°/0.001, -; 2-EtC6H4, H, 92-3°, 80°/0.001, -; 4-EtC6H4, H, 103-4°, 80°/0.001, -; 2,3-Me2C6H3, H, 97°, 80°/0.001, -; 2,4-Me2C6H3, H, 91°, 75°/0.001, -; 2,5-Me2C6H3, H, 84-6°, 75°/0.001, -; 2,6-Me2C6H3, H, 89-90°, 80°/0.001, -; 3,4-Me2C6H3, H, 73°, 80°/0.001, -; 3,5-Me2C6H3, H, 83-5°, 80°/0.001, -; 2,4,6-Me3C6H2, H, 139-40°, 90°/0.001, -; 2-HOC6H4, H, sublimes 167-9°, 110°/0.001, -; 3-HOC6H4, H, 131-2°, 115°/0.001, -; 4-HOC6H4, H, 172-3°, 120°/0.001, -; 2-MeOC6H4, H, 50-50.5°, 90°/0.001, -; 3-MeOC6H4, H, 75°, 105°/0.001, -; 4-MeOC6H4, H, 112°, 105°/0.001, -; 2-EtOC6H4, H, 141-2°, 110°/0.001, -; 1-C10H7, H, 102-3°, 100°/0.001, -; 2-C10H7, H, 146-7.5°, 120°/0.001, -; 2-fluorenyl, H, 201-2°, 160°/0.001, -; 9-fluorenyl, H, sublimes, 160°/0.001, -; 4-stilbenyl, H, 213-14°, 180°/0.001, -; azobenzene, H, 178-9°, 120°/0.001, -; 1-(2-HOC10H6), H, 168-9.5°, 140°/0.001, -; 2-PhC6H4, H, 99-101°, 100°/0.001, -; 4-PhC6H4, H, 200°, 190°/0.001, -; 2-pyridyl, H, 75-7°, 75°/0.001, -; 3-pyridyl, H, 127-8°, 110°/0.001, -; 5-isoquinolyl, H, 202-4°, 155°/0.001, -; 8-isoquinolyl, H, 215°, 140°/0.001, -; Ph, Me, 26-7°, 120°/11, 1.4681; Ph, Et, -, 120°/11, 1.4680; Ph, iso-Pr, 88-9°, 80°/0.001, -; PhCH2, Ph, 88-9°, 80°/0.001, -; 2-MeC6H4, Me, -, 125°/11, 1.4729; 2-MeC6H4, Et, -, 130°/11, 1.4731; 1-C10H7, Ph, 97-9°, 130°/0.001, -; 2-C10H7, Ph, 75-7°, 140°/0.001, -; Ph, Ph, 71-2°; 100°/0.001, -. Following (F3CCONH)2R were also prepared (R, m.p., and b.p./mm. given): CH2CH2, 204-6°, 140°/0.001; (CH2)3, 116-17°, 110°/0.005; (CH2)4, 155-7°, 120°/0.002; (CH2)5, 110-12°, 140°/0.002; (CH2)6, 121-3°, 150°/0.002; 1,2-C6H4, 158-8.5°, 130°/0.002; 1,3-C6H4, sublimes 225-8°, 140°/0.002; 1,4-C6H4, 249-50°, 160°/0.01; 4-methyl-1,2-phenylene, sublimes 197-9°, 150°/0.002; 4-methyl-1,3-phenylene, 183-4°, 160°/0.002; 5-methyl-1,4-phenylene, 190.5-1.5°, 150°/0.008; 2,2′-C6H4C6H4, 161-2°, 160°/0.001; 2,2′-C6H4CH:CHC6H4, sublimes 270°, 195°/0.01, -. Following CF3CF2CONHR were prepared (R, m.p., and b.p./0.001 mm. given): Ph, 98-9°, 65°; 2-MeC6H4, 78-9°, 65°; 3-MeC6H4, 52-3°, 70°; 4-MeC6H4, 111-12°, 75°; 2-EtC6H4, 64-5°, 70°; 4-EtC6H4, 121-2°, 80°; 2,3-Me2C6H3, 89-90°, 80°; 2,4-Me2C6H3, 55-7°, 75°; 2,5-Me2C6H3, 101-2°, 80°; 2,6-Me2C6H3, 108-9°, 80°; 3,4-Me2C6H3, 82-3°, 80°; 3,5-Me2C6H3, 94-5°, 80°; 2,4,6-Me3C6H2, 90-1°, 90°. Also prepared were: 2-trifluoroacetylpyrrole, m. 48.5°, 1,4-bis(trifluoroacetyl)piperazine, m. 111.5-12.5°, and 3-trifluoroacetylinodle m. 215-16°.

Monatshefte fuer Chemie published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, COA of Formula: C6H10F3NO.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Smith, Christine C. published the artcileThe synthesis and application of a diazirine-modified uridine analogue for investigating RNA-protein interactions, COA of Formula: C6H10F3NO, the publication is RSC Advances (2014), 4(89), 48228-48235, database is CAplus.

The roles played by many ncRNAs remain largely unknown. Similarly, relatively little is known about the RNA binding proteins involved in processing ncRNA. Identification of new RNA/RNA binding protein (RBP) interactions may pave the way to gain a better understanding of the complex events occurring within cells during gene expression and ncRNA biogenesis. The development of chem. tools for the isolation of RBPs is of paramount importance. In this context, we report on the synthesis of the uridine phosphoramidite U^Dz that bears a diazirine moiety on the nucleobase. RNA probes containing U^Dz units were irradiated in the presence of single-stranded DNA binding protein (SSB), which is also known to bind ssRNAs, and shown to efficiently (15% yield) and selectively cross-link to the protein. The corresponding diazirine-modified uridine triphosphate U^DzTP was synthesized and its capacity to act as a substrate for the T7 RNA polymerase was tested in transcription assays. U^DzTP was accepted with a maximum yield of 38% for a 26mer RNA containing a single incorporation and 28% yield for triple consecutive incorporations. Thus, this uridine analog represents a convenient biochem. tool for the identification of RNA binding proteins and unraveling the role and function played by ncRNAs.

RSC Advances published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C7H13ClNNaO5S, COA of Formula: C6H10F3NO.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Sleevi, P. published the artcileTrifluoroacetyl chloride for characterization of organic functional groups by fluorine-19 nuclear magnetic resonance spectrometry, Formula: C6H10F3NO, the publication is Analytical Chemistry (1979), 51(12), 1931-4, database is CAplus.

The potential utility of trifluoroacetyl chloride as an anal. ¹⁹F NMR reagent to characterize alcs., phenols, thiols, and primary and secondary amines is discussed. The ¹⁹F chem. shift and yield data for trifluoroacetyl derivatives of approx. 50 model compounds are presented. The importance of an added organic base (2,6-lutidine) in derivative preparation for phenols, and primary and secondary amines is also discussed.

Analytical Chemistry published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C18H34N4O5S, Formula: C6H10F3NO.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics