Related Products of 3073-59-4, A common heterocyclic compound, 3073-59-4, name is N,N’-(Hexane-1,6-diyl)diacetamide, molecular formula is C10H20N2O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Example 11 (Synthesis of methyl 1,6-hexamethylenedicarbamate) A glass test tube (outer diameter: 10 mm; length: 100 mm) having a cap was filled with 0.112 g (2.78 mmol) of magnesium oxide, 0.010 g (0.0275 mmol) of zinc(II) trifluoromethanesulfonate, 0.502 g (2.50 mmol) of hexamethylenebis(acetamide), and 0.905 g (10.0 mmol) of dimethyl carbonate, and a reaction was conducted at 180C for 2 hours. After cooling to room temperature, the resultant reaction solution was analyzed by gas chromatography. As a result, it was found that the conversion of 1,6-hexamethylenediacetamide was 99.8%, the yield of methyl 1,6-hexamethylenedicarbamate was 83.9 mol%, and the yield of methyl 1,6-hexamethylenemonocarbamate mono acetamide was 8.1%.
The synthetic route of 3073-59-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Ube Industries, Ltd.; EP2325167; (2011); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics