Category: 28797-48-0

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 28797-48-0, name is 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one

EXAMPLE 7 5,11-Dihydro-11-[[[2-(1-ethyl-2-pyrrolidinyl)ethyl]amino]acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Prepared analogously to Example 1 from 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 2-(2-aminoethyl)-1-ethylpyrrolidine. Yield: 9.5% of theory, Mp.: 109-111 C. (ethyl acetate/cyclohexane 2/1 v/v).

According to the analysis of related databases, 28797-48-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Mihm; Gerhard; Eberlein; Wolfgang; Engel; Wolfhard; Trummlitz; Gunter; Mayer; Norbert; de Jonge; Adrian; Doods; Henri; US5002943; (1991); A;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Application of 28797-48-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 28797-48-0, name is 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

EXAMPLE 36 11-[[4-[2-[2-(Diethylamino)ethoxy]ethyl]-1-piperidinyl]-acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Prepared analogously to Example 1 from 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-[2-[2-(diethylamino)ethoxy]ethyl]piperidine (Bp0.009 mmHg 96-102 C.) in a yield of 46% of theory. Colourless crystals, m.p. 130-131 C. (acetonitrile).

The synthetic route of 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Dr. Karl Thomae, GmbH; US5175158; (1992); A;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 28797-48-0, name is 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one, This compound has unique chemical properties. The synthetic route is as follows., Safety of 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one

EXAMPLE 7 5,11-Dihydro-11-[[[2-(1-ethyl-2-pyrrolidinyl)ethyl]amino]acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Prepared analogously to Example 1 from 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 2-(2-aminoethyl)-1-ethylpyrrolidine. Yield: 9.5% of theory, Mp.: 109-111 C. (ethyl acetate/cyclohexane 2/1 v/v).

According to the analysis of related databases, 28797-48-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Mihm; Gerhard; Eberlein; Wolfgang; Engel; Wolfhard; Trummlitz; Gunter; Mayer; Norbert; de Jonge; Adrian; Doods; Henri; US5002943; (1991); A;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Adding a certain compound to certain chemical reactions, such as: 28797-48-0, name is 11-(2-Chloroacetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one, belongs to amides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 28797-48-0, Formula: C14H10ClN3O2

EXAMPLE 13 5,11-Dihydro-11-[[4-(1-methyl-4-piperidinyl)-1-piperidinyl]acetyl]- 6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Prepared analogously to Example 1 from 11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-(1-methyl-4-piperidinyl)piperidine in a yield of 23% of theory. Colourless crystals, m.p. 208-211 C. (ethyl acetate).

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Reference:
Patent; Dr. Karl Thomae, GmbH; US5175158; (1992); A;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics