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Two electropolymerizable monomers with a methoxytriphenylamine core linked via amide groups to two triphenylamine (TPA) or N-phenylcarbazole (NPC) terminal groups, namely 4,4′-bis(4-diphenylaminobenzamido)-4 ”-methoxytriphenylamine (MeOTPA-(TPA)(2)) and 4,4′-bis(4 ”-(carbazol-9-yl)benzamido)-4-methoxytriphenylamine (MeOTPA-(NPC)(2)), were synthesized and characterized by FTIR and H-1 NMR spectroscopy, mass spectrometry, and cyclic voltammetry. The electrochemical polymerization reactions of these MeOTPA-cored monomers over indium tin oxide (ITO) electrode allow the generation of electroactive poly(amide-amine) films. The electro-generated polymer films exhibited reversible redox processes and multi-colored electrochromic behaviors upon electro-oxidation, together with moderate coloration efficiency and cycling stability. The optical density changes (Delta OD) were observed in the range of 0.18-0.68 at specific absorption maxima, with the calculated coloration efficiencies of 42-123 cm(2)/C. Single-layer electrochromic devices using the electrodeposited polymer films as active layers were fabricated for the preliminary investigation of their electrochromic applications.

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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Properties and Exciting Facts About (S)-2-Aminopropan-1-ol

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In an article, author is Guo, Ting, once mentioned the application of 2749-11-3, Name: (S)-2-Aminopropan-1-ol, Name is (S)-2-Aminopropan-1-ol, molecular formula is C3H9NO, molecular weight is 75.11, MDL number is MFCD00064412, category is amides-buliding-blocks. Now introduce a scientific discovery about this category.

Sulfonated 2D Covalent Organic Frameworks for Efficient Proton Conduction

Open 1D channels found in covalent organic frameworks are unique and promising to serve as pathways for proton conduction; how to develop high-rate yet stable transporting systems remains a substantial challenge. Herein, this work reports a strategy for exploring proton-conducting frameworks by engineering pore walls and installing proton-containing polymers into the pores. Amide-linked and sulfonated frameworks were synthesized from imine-linked precursors via sequentially engineering to oxidize into amide linkages and to further anchor sulfonic acid groups onto the pore walls, enabling the creation of sulfonated frameworks with high crystallinity and channel ordering. Integrating sulfonated polyether ether ketone chains into the open channels enables proton hopping to across the channels, greatly increases proton conductivity and enables a stable continuous run. These results suggest a way to explore proton-conducting COFs via systematic engineering of the wall and space of the open nanochannels.

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Properties and Exciting Facts About (S)-2-Aminopropan-1-ol

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In an article, author is Guo, Ting, once mentioned the application of 2749-11-3, Name: (S)-2-Aminopropan-1-ol, Name is (S)-2-Aminopropan-1-ol, molecular formula is C3H9NO, molecular weight is 75.11, MDL number is MFCD00064412, category is amides-buliding-blocks. Now introduce a scientific discovery about this category.

Sulfonated 2D Covalent Organic Frameworks for Efficient Proton Conduction

Open 1D channels found in covalent organic frameworks are unique and promising to serve as pathways for proton conduction; how to develop high-rate yet stable transporting systems remains a substantial challenge. Herein, this work reports a strategy for exploring proton-conducting frameworks by engineering pore walls and installing proton-containing polymers into the pores. Amide-linked and sulfonated frameworks were synthesized from imine-linked precursors via sequentially engineering to oxidize into amide linkages and to further anchor sulfonic acid groups onto the pore walls, enabling the creation of sulfonated frameworks with high crystallinity and channel ordering. Integrating sulfonated polyether ether ketone chains into the open channels enables proton hopping to across the channels, greatly increases proton conductivity and enables a stable continuous run. These results suggest a way to explore proton-conducting COFs via systematic engineering of the wall and space of the open nanochannels.

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Can You Really Do Chemisty Experiments About C3H9NO

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2749-11-3, Name is (S)-2-Aminopropan-1-ol, molecular formula is C3H9NO, Quality Control of (S)-2-Aminopropan-1-ol, belongs to amides-buliding-blocks compound, is a common compound. In a patnet, author is Dorame-Miranda, R. F., once mentioned the new application about 2749-11-3.

Limonia acidissima and Citrullus lanatus fruit seeds: Antimicrobial, thermal, structural, functional and protein identification study

An antimicrobial characterization along with thermal, structural, functional properties of L. acidissima and C. lanatus seeds were studied. Key proteins were identified in L. acidissima and C. lanatus seeds. The antimicrobial activity of L. acidissima protein hydrolysates was comparatively better than those of C. lanatus against the indicator strains used, i.e., Salmonella typhi, Pseudomonas aeruginosa, Escherichia coll. and Klebsiella pneumonia. The denaturation temperature for L. acidissima and C. lanatus protein hydrolysates were 92 and 72 degrees C, respectively. The FTIR analysis showed the presence of amide A, amide I, amide III and amide VI bands in the protein hydrolysates. The emulsifying activity index of the L. acidissima and C. lanatus seed protein hydrolysates were 53 and 29 m(2) /g, respectively. The emulsifying stability index for both hydrolysates was around 79%. The LCMS profile showed 4 proteins in L. acidisssima and 21 proteins in C. lanatus.

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In an article, author is Ahmad, T., once mentioned the application of 2749-11-3, Name: (S)-2-Aminopropan-1-ol, Name is (S)-2-Aminopropan-1-ol, molecular formula is C3H9NO, molecular weight is 75.11, MDL number is MFCD00064412, category is amides-buliding-blocks. Now introduce a scientific discovery about this category.

The construction of a lanthanide coordination polymer as ratiometric luminescent H2PO4- sensor

Ratiometric luminescence sensing has received particular attention as a technique with potential to provide precise and quantitative analyses. In this work, lanthanide coordination polymer Terp-TMC-Ln was synthesized, and tunable emission colors were achieved by altering the Eu3+/Tb3+ molar ratio. Besides, the appropriate triplet excited state energy of the terpyridine unit and the hydrogen bonding site of amide moiety enable Terp-TMC-Eu1Tb1 an ideal ratiometric and calorimetric luminescent anion sensor, to sensor and visualize H2PO4- over a wide concentration range. (C) 2017 Elsevier Ltd. All rights reserved.

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Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer’s disease

A series of urolithin amide (i.e., URO-4-URO-10 and THU-4-THU-10) derivatives was designed and synthesized, and their chemical structures were confirmed with spectroscopic techniques and elemental analysis. The title compounds and synthesis intermediates (THU-1-THU-10 and URO-1-URO-10) were evaluated for their potential to inhibit acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and monoamine oxidase B (MAO-B). Compounds THU-4 and THU-8 were found to be the most potent inhibitors for the cholinesterases and MAO-B, respectively. The docking studies were also employed to evaluate the binding modes of the most active compounds with AChE, BuChE, and MAO-B. Furthermore, the moderate-to-strong activities of the compounds were also displayed in amyloid-beta inhibition and antioxidant assay systems. The results pointed out that the urolithin scaffold can be employed in drug design studies for the development of multitarget ligands acting on various cascades shown to be important within the pathophysiology of Alzheimer’s disease.

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A polyacrylamide-based silica stationary phase for the separation of carbohydrates using alcohols as the weak eluent in hydrophilic interaction liquid chromatography

A hydrophilic interaction liquid chromatography (HILIC) stationary phase was prepared by a two-step synthesis method, immobilizing polyacrylamide on silica sphere particles. The stationary phase (named PA, 5 mu m dia) was evaluated using a mixture of carbohydrates in HILIC mode and the column efficiency reached 121,000 N m(-1). The retention behavior of carbohydrates on PA stationary phase was investigated with three different organic solvents (acetonitrile, ethanol and methanol) employed as the weak eluent. The strongest hydrophilicity of PA stationary phase was observed in both acetonitrile and methanol as the weak eluent, when compared with another two amide stationary phases. Attributing to its high hydrophilicity, three oligosaccharides (xylooligosaccharide, fructooligosaccharide and chitooligosaccharides) presented good retention on PA stationary phase using alcohols/water as mobile phase. Finally, PA stationary phase was successfully applied for the purification of galactooligosaccharides and saponins of Paris polyphylla. It is feasible to use safer and cheaper alcohols to replace acetonitrile as the weak eluent for green analysis and purification of polar compounds on PA stationary phase. (C) 2017 Published by Elsevier B.V.

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Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 2749-11-3, Name is (S)-2-Aminopropan-1-ol, molecular formula is C3H9NO, belongs to amides-buliding-blocks compound, is a common compound. In a patnet, author is Yoshimura, Fumihiko, once mentioned the new application about 2749-11-3, Formula: C3H9NO.

Backbone Cleavages of Protonated Peptoids upon Collision-Induced Dissociation: Competitive and Consecutive B-Y and A(1)-Y-X Reactions

Mass spectrometric techniques and more particularly collision-induced dissociation (CID) experiments represent a powerful method for the determination of the primary sequence of (bio)molecules. However, the knowledge of the ion fragmentation patterns say the dissociation reaction mechanisms is a prerequisite to reconstitute the sequence based on fragment ions. Previous papers proposed that protonated peptoids dissociate following an oxazolone-ring mechanism starting from the O-protonation species and leading to high mass Y sequence ions. Here we revisit this backbone cleavage mechanism by performing CID and ion mobility experiments, together with computational chemistry, on tailor-made peptoids. We demonstrated that the B/Y cleavages of collisionally activated O-protonated peptoids must involve the amide nitrogen protonated structures as the dissociating species, mimicking the CID behavior of protonated peptides. Upon the nucleophilic attack of the oxygen atom of the N-terminal adjacent carbonyl group on the carbonyl carbon atom of the protonated amide, the peptoid ions directly dissociate to form an ion-neutral complex associating an oxazolone ion to the neutral truncated peptoid residue. Dissociation of the ion/neutral complex predominantly produces Y ions due to the high proton affinity of the secondary amide function characteristic of truncated peptoids. Whereas the production of Y-x ions from acetylated peptoids also involves the B/Y pathway, the observation of abundant Y-x ions from non-acetylated peptoid ions is shown in the present study to arise from an A(1)-Y-x mechanism. The consecutive and competitive characters of the A(1)-Y-x and the B/Y mechanisms are also investigated by drift time-aligned CID experiments.

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The effects of gluten protein substation on chemical structure, crystallinity, and Ca in vitro digestibility of wheat-cassava snacks

Gluten protein based snacks have been a major concern for allergen, low nutrition and physio-chemical properties. In this study, wheat flour (WF) was replaced with cassava starch (CS) at different levels [10, 20, 30, 40 and 50%(w/w)] to prepare fried snacks. The addition of CS significantly (P < 0.05) increased hardness and pasting properties while gluten network, oil uptake, water holding capacity, and expansion were decreased. Fourier transform infrared spectroscopy revealed that the secondary structure of amide I, alpha-helix (1650-1660 cm(-1)), along with amide II region (1540 cm(-1)) changed when CS was added. Starch-protein complex was identified by X-ray diffraction analysis while no starch-protein-lipid complex was observed. The micrographs from scanning electron microscopy showed that starch-protein matrix was interrupted when >= 40%(w/w) CS was added. Furthermore, in vitro calcium bioavailability was decreased slightly with the addition of CS. The results suggest the feasibility of adding 40% CS as an alternative to WF in snacks.

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Related Products of 2749-11-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 2749-11-3, Name is (S)-2-Aminopropan-1-ol, SMILES is C[C@H](N)CO, belongs to amides-buliding-blocks compound. In a article, author is Freitas, Hercules Rezende, introduce new discover of the category.

Novel amide derivatives of 3-phenylglutaric acid as potent soluble epoxide hydrolase inhibitors

Soluble epoxide hydrolase (sEH) enzyme plays an important role in the metabolism of endogenous chemical mediators, epoxyeicosatrienoic acids, which are involved in the regulation of blood pressure and inflammation. According to the pharmacophoric model suggested for sEH inhibitors, some new amide-based derivatives of 3-phenylglutaric acid were designed, synthesized and biologically evaluated. Docking study illustrated that the amide group as a primary pharmacophore had a suitable distance from the three amino acids of Tyr383, Tyr466 and Asp335 for effective hydrogen binding. Most of the compounds showed moderate to high sEH inhibitory activities in in vitro test in comparison with 12-(3-Adamantan-1-yl-ureido)-dodecanoic acid, as a potent urea-based sEH inhibitor. Compound 6o with phenethyl in R position exhibited the highest activity with IC50 value of 0.5 nM. Graphic abstract In this study, some new amide-based derivatives of 3-phenylglutaric acid were designed, synthesized and biologically evaluated. Most of the synthesized compounds provided nanomolar range inhibition against sEH enzyme. The best observed IC50 value was 0.5 nM. Incorporating a carboxylic moiety into these structures by forming carboxylate salts would increase the solubility and improving physicochemical properties. [GRAPHICS] .

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