Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 259796-12-8, name is 3,5-Dichloro-N-methoxy-N-methylbenzamide, A new synthetic method of this compound is introduced below., Safety of 3,5-Dichloro-N-methoxy-N-methylbenzamide
3,5-Dichloro-N-methoxy-N-methylbenzamide 12b (1.0 g, 4.27 mmol) was dissolved in 20 mL of dry tetrahydrogenEthylmagnesium chloride reagent (8.5 mL, 8.5 mmol, 1 M/THF) was added dropwise to furan at 0 C and allowed to react at room temperature for 2 hours. Add 20mLSaturate the ammonium chloride solution and quench the reaction. Extracted with ethyl acetate (825 mg, colorless oil), yield: 95.2%.
The synthetic route of 259796-12-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Zhejiang Haizheng Pharmaceutical Co., Ltd.; Guan Dongliang; Wang Zhongli; Bai Hua; Liu Zhubo; Meng Lichen; Zhao Weifeng; Ling Long; Wang Yan; (78 pag.)CN109574927; (2019); A;,
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