Application of 2564-07-0, The chemical industry reduces the impact on the environment during synthesis 2564-07-0, name is 2-Chloro-N-(2,3-dimethylphenyl)acetamide, I believe this compound will play a more active role in future production and life.
The procedure described in Example 8 was followed, substituting the product from Example 17A for N-chloroacetyl-3-nitroaniline, to provide the title compound (32% yield as a white solid. mp 124-126 C.; 1H NMR (300 MHz, DMSO-d6) ? 2.12 (s, 3H), 2.26 (s, 3H), 2.72 (m, 4H), 3.21 (s, 2H), 3.69 (m, 4H), 6.94 (dd, 1H, J=7.8, 4.8 Hz), 6.99 (br d, 1H, J=7.4 Hz), 7.07 (dd, 1H, J=7.4, 7.4 Hz), 7.45 (br d, 1H, J=7.8 Hz), 8.08 (dd, 1H, J=7.8, 2.0 Hz), 8.42 (dd, 1H, 4.8, 2.1 Hz), 9.42 (br s, 1H); MS (DCI/NH3) m/e 350 (M+H)+; Anal. calcd for C20H23N50.0.10H2O: C, 68.39; H, 6.66; N, 19.94. Found: C, 68.74; H, 6.58; N, 19.56.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Chloro-N-(2,3-dimethylphenyl)acetamide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Stewart, Andrew O.; Kolasa, Teodozyj; US2003/232836; (2003); A1;,
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