25412-53-7, name is 4-Acetamidobenzylamine, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Product Details of 25412-53-7
EXAMPLE 50 N-(4-acetylamino-phenylmethyl)-3-(4′-trifluoromethylbiphenyl-2-carbonylamino)-benzoic acid amide Prepared analogously to Example 7 from 3-(4′-trifluoromethylbiphenyl-2-carbonylamino)-benzoic acid and 4-acetylaminobenzylamine in dichloromethane with the addition of propanephosphonic acid cycloanhydride and N-methylmorpholine. Yield:38% of theory Rf value:0.60 (silica gel; dichloromethane/ethanol=9:1)
The synthetic route of 25412-53-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Priepke, Henning; Hauel, Norbert; Thomas, Leo; Mark, Michael; Dahmann, Georg; US2002/32238; (2002); A1;,
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