2430-27-5, name is 2-Propylpentanamide, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 2430-27-5
General procedure: To a solution of the appropriate drug (D1-CONH2,1.00 mmol) in CH2Cl2 (5 mL) at 0 – 5 oC wasadded oxalyl chloride (1.30 mmol) drop-wise and refluxed for 24 h. The reactionmixture was concentrated and the residue was dissolved in DCE (5 mL). To thiswas added a solution of 11 (2.00mmol) in DCE (5 mL) and stirred for 24 h. The reaction mixture was concentratedand the residue was partitioned between EtOAc (20mL) and water (10 mL). Theorganic layer was washed with water and brine (10 mL each), dried (Na2SO4),concentrated and purified by silica gel column chromatography to afford thetitle compounds
Statistics shows that 2430-27-5 is playing an increasingly important role. we look forward to future research findings about 2-Propylpentanamide.
Reference:
Article; Jain, Arun K.; Gund, Machhindra G.; Desai, Dattatraya C.; Borhade, Namdev; Senthilkumar, Subrayan P.; Dhiman, Mini; Mangu, Naveen K.; Mali, Sunil V.; Dubash, Nauzer P.; Halder, Somnath; Satyam, Apparao; Bioorganic Chemistry; vol. 49; (2013); p. 40 – 48;,
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