Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2015-19-2, name is 5-Amino-2-chlorobenzenesulfonamide, This compound has unique chemical properties. The synthetic route is as follows., 2015-19-2
The compound 5 (1.24 g, 6.0 mmol), formic acid (2.23 g, 48.0 mmol) and sodium formate (82 mg, 1.2 mmol) were placed into a flask. The reaction was monitored with TLC and complete after 10 h of stirring at room temperature. The resulting mixture was poured onto 50 mL of water, and the suspension was stirred for 10 min. After stewing at 10 C for 10 min, the white precipitate was filtered to give the intermediate 6m.
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Reference:
Article; Pan, Li; Jiang, Ying; Liu, Zhen; Liu, Xing-Hai; Liu, Zhuo; Wang, Gang; Li, Zheng-Ming; Wang, Di; European Journal of Medicinal Chemistry; vol. 50; (2012); p. 18 – 26;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics