Category: 167316-28-1

On December 21, 2000, Wagner, Alain; Mioskowski, Charles; Mohar, Barbara; Desmurs, Jean-roger; Le Guyader, Frederic; Schlama, Thierry published a patent.Application of 167316-28-1 The title of the patent was Sulfonamides and carboxamides and their use in asymmetrical catalysis. And the patent contained the following:

Optically active diamines were converted to their monosulfonamides with fluorinated alkane- or arenesulfonyl halides. The resulting sulfona,ides were used as ligands in the stereoselective reduction of ketones or in the stereoselective oxidation of racemic alcs. Thus, (1S,2S)-1,2-cyclohexanediamine was treated with F3CSO2Cl to give (1S,2S)-N-trifluoromethylsulfonyl-1,2-cyclohexanediamine (I). I was used together with [RuCl2(p-cymene)]2 to reduce PhCOMe to (S)-HOCHPhMe and to preferentially oxidize (S)-HOCHPhMe to PhCOMe, leaving enriched (R)-HOCHPhMe. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Application of 167316-28-1

The Article related to diamine monosulfonamide preparation ligand asym reduction oxidation, General Organic Chemistry: Synthetic Methods and other aspects.Application of 167316-28-1

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 21, 2010, Liu, Chen; Lu, Yixin published an article.HPLC of Formula: 167316-28-1 The title of the article was Primary amine/(+)-CSA salt-promoted organocatalytic conjugate addition of nitro esters to enones. And the article contained the following:

The combination of 9-amino-9-deoxy-epi-cinchonine and (+)-CSA resulted in a novel primary amine-based organocatalyst for effective iminium activation of 伪,尾-unsaturated ketones. Such a catalytic system could catalyze the conjugate addition of nitroacetate to enones in a highly enantioselective manner, affording the desired adducts in high yields and with up to 99% ee. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).HPLC of Formula: 167316-28-1

The Article related to substituted nitroester asym preparation, nitroacetate unsaturated ketone asym michael addition chiral amine csa, General Organic Chemistry: Synthetic Methods and other aspects.HPLC of Formula: 167316-28-1

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 23, 2021, Fan, Qinghua; Zhang, Shanshan; Chen, Fei; He, Yanmei published a patent.Recommanded Product: 167316-28-1 The title of the patent was Asymmetric hydrogenation kinetic resolution of racemic polysubstituted dihydroisoquinoline. And the patent contained the following:

The invention discloses an asym. hydrogenation kinetic resolution method of racemic polysubstituted dihydroisoquinoline, which can realize the resolution of racemic polysubstituted dihydroisoquinoline compounds, and obtain a single optical isomer of polysubstituted chiral tetrahydroisoquinoline compounds and polysubstituted chiral dihydroisoquinoline compounds with certain optical purity. The asym. hydrogenation kinetic resolution method comprises the following steps: in the presence of chiral diamine metal catalyst, the mixture containing enantiomers of polysubstituted dihydroisoquinoline compounds is asym. hydrogenated with hydrogen. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Recommanded Product: 167316-28-1

The Article related to asym hydrogenation kinetic resolution racemic polysubstituted dihydroisoquinoline, Heterocyclic Compounds (One Hetero Atom): Quinolines and Isoquinolines and other aspects.Recommanded Product: 167316-28-1

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 19, 1995, Hashiguchi, Shohei; Fujii, Akio; Takehara, Jun; Ikariya, Takao; Noyori, Ryoji published an article.Safety of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide The title of the article was Asymmetric Transfer Hydrogenation of Aromatic Ketones Catalyzed by Chiral Ruthenium(II) Complexes. And the article contained the following:

A chiral Ru(II) complex, prepared from [RuCl2(η6-mesitylene)]2 and (1S,2S)-N-p-toluenesulfonyl-1,2-diphenylethylenediamine, effects a highly enantioselective transfer hydrogenation of various aromatic alkyl ketones by iso-PrOH. The reduction of acetophenone in a 0.1M solution of iso-PrOH containing the Ru catalyst (substrate/catalyst (S/C) mole ratio = 200) and KOH (5 equiv to Ru atom) proceeds at room temperature to give (S)-1-phenylethanol in 97% ee and 95% yield. The enantioselectivity is slightly lowered as the reaction proceeds owing to the reversibility of the transfer hydrogenation. In a similar manner, a range of simple aromatic ketones (S/C = 200-500) are convertible to secondary alcs. with high enantiomeric purity. A relevant catalyst precursor was obtained by reacting [RuCl2(η6-benzene)]2 and (1S,2S)-N-trifluoromethanesulfonyl-1,2-diphenylethylenediamine in a 1:4 mol ratio in iso-PrOH. The mol. structure was determined by single-crystal x-ray anal. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Safety of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide

The Article related to crystal structure ruthenium benzene sulfonylethylenediamine complex, ruthenium sulfonylethylenediamine transfer hydrogenation catalyst ketone, Physical Organic Chemistry: Oxidation-Reduction, Including Dehydrogenation and Hydrogenolysis and other aspects.Safety of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 15, 2014, Xuan, Yining; Luo, Yan published an article.COA of Formula: C15H15F3N2O2S The title of the article was Synthesis of bifunctional sulfonamides and study on the catalytic asymmetric aldol reaction. And the article contained the following:

A series of monosulfonamide were synthesized from chiral diamines and were used as the catalysts for asym. aldol reaction between acetone and p-nitrobenzaldehyde. The structure effects of the diamines and the sulfonyl groups were investigated. The effect of additive was also studied. Among all the screened catalysts, the monosulfonamide derived from (1S,2S)-1, 2-diphenylethane-1,2-diamine was identified as the best catalyst for the reaction. In the presence of the catalyst and benzoic acid, the reaction was achieved with moderate yield and enantioselectivity. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).COA of Formula: C15H15F3N2O2S

The Article related to bifunctional sulfonamide chiral diamine catalytic asym aldol reaction, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.COA of Formula: C15H15F3N2O2S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Matsunami, Asuka; Kayaki, Yoshihito; Ikariya, Takao published an article in 2015, the title of the article was Enhanced Hydrogen Generation from Formic Acid by Half-Sandwich Iridium(III) Complexes with Metal/NH Bifunctionality: A Pronounced Switch from Transfer Hydrogenation.Reference of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide And the article contains the following content:

By switching the catalytic function from transfer hydrogenation based on the metal/NH bifunctionality, facile dehydrogenation of formic acid was achieved by amido- and hydrido(amine)-Ir complexes derived from N-triflyl-1,2-diphenylethylenediamine (TfDPEN) at ambient temperature even in the absence of base additives. Further acceleration was observed by the addition of water, leading to a maximum turnover frequency above 6000 h-1. A proton-relay mechanism guided by the protic amine ligand and water is postulated for effective protonation of metal hydrides. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Reference of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide

The Article related to hydrogen storage material formic acid dehydrogenation catalyst iridium complex, cooperative effects, dehydrogenation, homogeneous catalysis, hydride ligands, iridium, Electrochemical, Radiational, and Thermal Energy Technology: Energy Handling, Transport, and Storage and other aspects.Reference of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 5, 2006, Marko, Istvan; De Paolis, Michael; Mignani, Gerard published a patent.Computed Properties of 167316-28-1 The title of the patent was Use of an aromatic carboxylic acid in an asymmetric catalysis reaction, particularly Aldol condensation, in combination with pyrrolidine-containing chiral derivatives of diamines, amino alcohols, carbonyls, and monosulfonyl compounds. And the patent contained the following:

The invention is related to the use of strong aromatic carboxylic acids of formula I [B = aromatic carbocycle; L = alkyl(en)yl; n = number of R substituents, especially 1-2; each R = independently various substituents on ring B, with at least 1 substituent representing an electron attracting group] in combination with pyrrolidine-containing chiral catalysts such as derivatives of diamines, amino alcs., carbonyls, monosulfonyl compounds, in asym. catalysis, particularly asym. aldolization or ketolization. Thus, 2-nitrobenzoic acid in combination with 2-pyrrolidinamide derivative II was used in an aldolization reaction of 4-nitrobenzaldehyde in CH3CN-H2O-acetone. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Computed Properties of 167316-28-1

The Article related to asym aldolization aryl carboxylic acid, aldol preparation asym catalysis, chiral catalyst asym aldol condensation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Computed Properties of 167316-28-1

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 17, 2009, Soltani, Omid; Ariger, Martin A.; Carreira, Erick M. published an article.Electric Literature of 167316-28-1 The title of the article was Transfer hydrogenation in water: enantioselective, catalytic reduction of (E)-β,β-disubstituted nitroalkenes. And the article contained the following:

A mild catalytic asym. transfer hydrogenation of β,β-disubstituted nitroalkenes is reported. Formic acid is used as a reductant in combination with an Ir catalyst. The reaction is conducted in water at low pH and open to air to give adducts in preparatively useful yield and selectivity. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Electric Literature of 167316-28-1

The Article related to nitropropylbenzene asym preparation, nitropropenylbenzene asym transfer hydrogenation iridium, iridium asym transfer hydrogenation catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Electric Literature of 167316-28-1

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 18, 2009, Martins, Jose E. D.; Wills, Martin published an article.Electric Literature of 167316-28-1 The title of the article was Ir(III) complexes of diamine ligands for asymmetric ketone hydrogenation. And the article contained the following:

The use of a combination of IrCl3 with a series of ligands derived from the C2-sym. diamine diphenylethanediamine (DPEN) forms a catalyst capable of the asym. hydrogenation of ketones in up to 85% ee. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Electric Literature of 167316-28-1

The Article related to arylalkanol asym preparation, arylketone asym hydrogenation iridium chiral diamine, chiral diaminepreparation iridium asym hydrogenation catalyst, diamine sulfonylation reductive amination and other aspects.Electric Literature of 167316-28-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 25, 2007, Kansal, Kinod Kumar; Ahmad, Suhail; Mariappan, Shanmugavel; Tyagi, Bhupendra; Perlman, Nurit; Le Paih, Jacques; Zanotti-Gerosa, Antonio published a patent.Recommanded Product: N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide The title of the patent was Processes for the synthesis of azetidinone. And the patent contained the following:

Provided were intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided were processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe (I). The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Recommanded Product: N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide

The Article related to azetidinone ezetimibe analog preparation drug delivery system, cholesterol absorption inhibitor azetidinone ezetimibe analog preparation, stereoselective reduction ruthenium catalyst ezetimibe preparation and other aspects.Recommanded Product: N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics