Category: 144-80-9

On July 8, 2022, Yang, Lei; Wu, Xiaona; Chen, Xiaoyu; Chen, Fei; Zheng, Xiaona; Song, Qinan; Liu, Xiang; Li, Miao published an article.COA of Formula: C8H10N2O3S The title of the article was Synergistic Removal of Nutrient Pollutants and Pharmaceutical and Personal Care Products (PPCPs) from Contaminated Groundwater: Macro- and Microelements and Microorganisms. And the article contained the following:

The synergistic removal performance of nutrient pollutants and pharmaceutical and personal care products (PPCPs) from contaminated groundwater, and the biogeochem. interactions of macro- and microelements-contaminants-microorganisms were further studied. The electrolysis-zeolite/basalt system proved to achieve better synergistic removal performance than all other purification systems considered, reaching average removal efficiencies of 85.8% for nutrient pollutants and 74.7% for PPCPs. Electrolysis not only enhanced the abundance and distribution of MOB and DNB, but also promoted the production of microelements Fe3+ (0.1 ± 0.1 mg/L) and Zn2+ (0.3 ± 0.3 mg/L). Macroelements Ca2+ and Mg2+ increased by 27.8 ± 2.7 and 16.5 ± 9.6 mg/L, resp., which significantly stimulated the activities of function microbials. Microelements Fe3+ exchanged from zeolite, Mn2+ from basalt, and Cu2+ from groundwater itself were crucial for enzyme activity. Meanwhile, Mn2+ was co-regulated by oxidation-reduction processes and ion-exchange strength. Thus, the electrolysis-zeolite/basalt system is a promising technol. for synergistic nutrient pollutant and PPCP removal from contaminated groundwater, especially in dispersive water supplied in the countryside of China. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).COA of Formula: C8H10N2O3S

The Article related to microelement microorganism synergistic removal nutrient groundwater pollutant, Waste Treatment and Disposal: Physical Treatment Of Aqueous Wastes and other aspects.COA of Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 15, 2022, Li, Xitong; Liang, Kaiming; Yang, Bo; Xiao, Ke; Duan, Huabo; Song, Guangqing; Zhao, Huazhang published an article.Formula: C8H10N2O3S The title of the article was Preparation and application of a targeted magnetically separated catalyst for sulfonamides degradation based on molecular dynamics selection and mechanism analysis. And the article contained the following:

As refractory pollutants, sulfonamides (SAs) are widely distributed in the aquatic environment. The existing methods for advanced oxidation used to remove SAs from water received wide attention. In this study, surface mol. imprinting technol. has been used to prepare targeted catalysts that can be rapidly separated The results showed that molecularly imprinted catalysts can significantly improve the removal capacity of sulfonamides. When compared to Fe3O4, the removal rates observed for 3 different SAs increased by 98, 20 and 61%, resp. over 480 min on target catalyst and a good magnetic separation effect was observed in short time. The theor. results show that the optimal imprinted conditions can be quickly determined by analyzing the energy variation in the optimized system. Combined with energy anal. and free radical detection, the effects of weak interactions such as hydrogen bonds and van der Waals forces on the selective recognition ability of the materials were determined The results also show that the selective recognition process mainly exists in the higher activity groups (-NH2 and -NH-) that connect to the benzene ring in SAs. The catalysts also maintain their targeted catalytic activity in complex water samples. The results show that computational chem. and mol. imprinting can be used to design and prepare a targeted catalyst quickly and analyze the mechanism of its targeted degradation process. This study can provide reference for the rapid design of targeted catalysts and an improvement in the degradation efficiency of refractory pollutants found in wastewater. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Formula: C8H10N2O3S

The Article related to sulfonamide surface mol imprinting degradation wastewater treatment, Waste Treatment and Disposal: Chemical Treatment Of Aqueous Wastes and other aspects.Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 15, 2021, Zhang, Lili; Zhang, Cheng; Lian, Keting; Liu, Chongxuan published an article.SDS of cas: 144-80-9 The title of the article was Effects of chronic exposure of antibiotics on microbial community structure and functions in hyporheic zone sediments. And the article contained the following:

Microbial communities in hyporheic zones (HZ) provide vital biogeochem. functions such as contaminant degradation for river ecosystems. Antibiotics are contaminants that have been increasingly detected in HZ sediments. In this study, sediments from different HZ locations in a contaminated river, Maozhou river, China were sampled and analyzed using qPCR and high-throughput sequencing to investigate the effect of antibiotic contamination on microbial community structures and functions in HZ sediments. Results indicated that types and concentrations of antibiotics in HZ sediments were heterogeneously distributed that were largely consistent with the distribution of antibiotic sources. Sediments near animal farm and hospital contained higher antibiotic concentrations compared with those from mainstream. The distribution of ARGs was well correlated with antibiotics. Bacterial indicator genera indicating differences between mainstream area and other sampling areas were pos. correlated with antibiotics, suggesting the influences of antibiotics on reshaping microbial community structures. PICRUSt revealed pos. relationships between antibiotics and predicted functional genes involved in defense, signal transduction, and recombination and repair. This imply the defensive response of microbial communities on antibiotic attack. These results indicated that antibiotic contamination in the watershed posed a potential risk on HZ microbial community structures and functions, which may further threaten river ecosystem functions. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).SDS of cas: 144-80-9

The Article related to antibiotic microbial community structure chronic exposure river ecosystem, antibiotic resistance genes, antibiotics, hyporheic zone, microbial community, sediments, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.SDS of cas: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 15, 2021, Sakurai, Karen Sayuri Ito; Pompei, Caroline Moco Erba; Tomita, Ines N.; Santos-Neto, Alvaro J.; Silva, Gustavo Henrique Ribeiro published an article.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Hybrid constructed wetlands as post-treatment of blackwater: An assessment of the removal of antibiotics. And the article contained the following:

New sanitation systems have been developed to treat, recover energy and nutrients, and permit reuse processes at the source of generation, minimizing water use and flow segregation. Thus, this study was carried out with the objective of evaluating the potential of hybrid constructed wetlands in the removal of organic matter, nutrients, pathogenic microorganisms, and 12 antibiotics from blackwater previously treated by an upflow anaerobic sludge blanket reactor. A hybrid system of constructed wetlands was used, comprised of a horizontal subsurface flow constructed wetland with a total volume of 0.60 m3 followed by a vertical subsurface flow constructed wetland with a total volume of 0.20 m3. Three different hydraulic retention times were comparatively tested (1.0, 2.0, and 3.0 days for the horizontal subsurface flow constructed wetland, and 1.1, 0.9, and 0.4 days for the vertical subsurface flow constructed wetland) in four distinct stages. The plant species used was Canna generalis. The results from this study demonstrate the potential of constructed wetlands as a suitable technol. for post-treatment of segregated domestic wastewater (anaerobically-digested blackwater). Efficient reduction of COD, BOD5, total nitrogen, and total phosphorus (74, 93, 50, and 61%, resp.) was achieved, with a hydraulic retention time of 3.0 and 1.1 days for horizontal and vertical subsurface flow constructed wetland, resp. (stage IV). The presence of ciprofloxacin was confirmed by chromatog. and mass spectrometric anal. in an average concentration of 442.6 ng. L-1 at the inflow of the horizontal subsurface flow constructed wetland, but was not observed at the outflow. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to ciprofloxacin canna phragmites anaerobic sludge blanket reactor, antibiotics removal, blackwater, hybrid constructed wetlands, new sanitation, post-treatment, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2021, Wang, Juan; Zhang, Peng-Li; Ansari, Mohammad Fawad; Li, Shuo; Zhou, Cheng-He published an article.COA of Formula: C8H10N2O3S The title of the article was Molecular design and preparation of 2-aminothiazole sulfanilamide oximes as membrane active antibacterial agents for drug resistant Acinetobacter baumannii. And the article contained the following:

A series of 2-aminothiazole sulfanilamide oximes were developed as new membrane active antibacterial agents to conquer the microbial infection. Benzoyl derivative 10c was preponderant for the treatment of drug-resistant A. baumannii infection in contrast to norfloxacin and exerted excellent biocompatibility against mammalian cells including erythrocyte and LO2 cell line. Meanwhile, it had ability to eradicate established biofilm to alleviate the resistance burden. Mechanism investigation elucidated that compound 10c was able to disturb the membrane effectively and inhibit lactic dehydrogenase, which led to cytoplasmic content leakage. The cellular redox homeostasis was interfered via the production of reactive oxygen and nitrogen species (RONS), which further contributed to respiratory pathway inactivation and reduction of GSH activity. This work indicated that 2-aminothiazole sulfanilamide oximes could be a promising start for the exploitation of novel antibacterial agents against pathogens. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).COA of Formula: C8H10N2O3S

The Article related to acinetobacter aminothiazole sulfanilamide oxime antibacterial mol design, a. baumannii, aminothiazole, antibacterial, oxime, sulfanilamide, Microbial, Algal, and Fungal Biochemistry: Antimicrobial Sensitivity and other aspects.COA of Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 30, 2022, Pu, Miao; Ailijiang, Nuerla; Mamat, Anwar; Chang, Jiali; Zhang, Qiongfang; Liu, Yifan; Li, Nanxin published an article.Name: N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Occurrence of antibiotics in the different biological treatment processes, reclaimed wastewater treatment plants and effluent-irrigated soils. And the article contained the following:

Reclaimed wastewater is increasingly being used for agricultural irrigation to address water scarcity, particularly in arid and semiarid areas. In this study, the occurrence and removal of 24 antibiotics were investigated in two wastewater treatment systems (WWTSs) and their irrigation areas located in the arid northwestern region of China. The different WWTSs included absorption-biodegradation (AB) + anaerobic-anoxic-oxic (AAO) and AAO + AAO + membrane bioreactor (MBR). Nineteen antibiotics were detected, with concentrations ranging from low to 60.8μg/L. The dominant antibiotic classes were quinolones (QNs) and macrolides (MLs) in winter, and MLs and sulfonamides (SAs) in summer. The AAO + AAO + MBR system exhibited better removal efficiencies for most antibiotics, improving their adsorption and biodegradation Except for ofloxacin (OFC) and norfloxacin (NFC), the concentrations of the detected antibiotics were higher in summer than in winter. However, the antibiotic removal efficiency increased by 2-141% in summer compared to winter due to the increase in microbial activity with temperature Even though reclaimed treatment water plants contributed to the removal of antibiotics, residual antibiotics still affected the soil environment after green irrigation. In irrigated soil, QNs were predominantly detected, with a maximum concentration of 150.9 ng/kg for NFC. An ecol. risk assessment showed that OFC, NFC, enrofloxacin, and lomefloxacin presented low or medium ecol. risks in at least two irrigated sites. Thus, more attention should be given to the reuse of reclaimed wastewater, as it may pose toxicity risks to organisms in the soil environment. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Name: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotics biol process reclaimed wastewater treatment plant soil, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.Name: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 1, 2021, Cysewski, Piotr; Jelinski, Tomasz; Procek, Dominika; Dratwa, Aleksandra published an article.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Solubility of Sulfanilamide and Sulfacetamide in neat solvents: Measurements and interpretation using theoretical predictive models, first principle approach and artificial neural networks. And the article contained the following:

Solubilities of Sulfanilamide and Sulfacetamide in neat solvents were both measured and collected from the literature. The set comprising 35 systems was interpreted in terms of the empirical and semi-empirical predictive models including Buchowski-Ksiazczak model (λh-equation), extended Buchowski’s model (λβ-equation), modified Apelblat equation, van’t Hoff-Yaws model, Non-Random Two Liquid (NRTL) model, Wilson model and the Weibull two-parameter extrapolation model. The advantage of corrected Akaike information criterion was used for precise quantification of the quality of each model. It turned out that the lowest values of this measure were found for the Buchowski-Ksiazczak approach indicating the best correlation with exptl. solubility data. Interestingly, λβ-equation and van’t Hoff-Yaws model give a fitting of almost the same quality but were slightly less accurate compared to λh-equation. The results of applied COSMO-RS computations suffered seriously from inaccuracies providing only a qual. guess of solubility Hence, machine learning procedure was applied for building a non-linear fully predictive model. The set of used mol. descriptors comes from COSMO-RS computations and characterizes intermol. interactions in pure solvents. Based on the quality of obtained machine learning model it is possible to confirm that the selected set of descriptors can be used for solubility modeling and carries the most important information necessary for quantifying of saturated solutions The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to solubility sulfanilamide sulfacetamide solvent theor model artificial neural network, Phase Equilibriums, Chemical Equilibriums, and Solutions: Nonelectrolytic Solutions and other aspects.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 1, 2021, Rahimpour, Elaheh; Acree, William E. Jr.; Jouyban, Abolghasem published an article.Synthetic Route of 144-80-9 The title of the article was Prediction of sulfonamides’ solubilities in the mixed solvents using solvation parameters. And the article contained the following:

The exptl. solubility data of various sulfonamides in the binary solvent systems at various temperatures are collected from the literature and fitted to Jouyban-Acree model as an accurate cosolvency model for providing solubility prediction tools. In order to obtain predictive cosolvency models, the Jouyban-Acree model is combined with physicochem. parameters of the Abraham solvation parameters and the Hansen solubility parameters. Based on these computations, the generally trained versions of the combined models are proposed which enable one to predict the solubility of sulfonamides in the binary solvent mixtures at various temperatures with reasonable error levels. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Synthetic Route of 144-80-9

The Article related to sulfonamide solubility binary solvent system solvation parameter, Phase Equilibriums, Chemical Equilibriums, and Solutions: Nonelectrolytic Solutions and other aspects.Synthetic Route of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2021, Carvalho, Fernando Marques; So, Yuri Alves de Oliveira; Wernik, Alessandra Sofia Kiametis; Silva, Monica de Abreu; Gargano, Ricardo published an article.Computed Properties of 144-80-9 The title of the article was Accurate acid dissociation constant (pKa) calculation for the sulfachloropyridazine and similar molecules. And the article contained the following:

Accurate calculation of the acid dissociation constant (pKa) has fundamental importance for the description of mol. systems with pharmacol. activities. The search for a more appropriate procedure for its determination is always welcome and has aroused increasing interest from the scientific community. In this sense, this work presents a computational study involving the combination of ten DFT functionals (M062X, M06L, B3LYP, BLYP, PBEPBE, BP86, LC-BLYP, SPBE, CAM-B3LYP, LC-PBEPBE) and HF method, eight basis set functions (6-311G, 6-311 + G, 6-311G(d,p), 6-311 + G(d,p), 6-311+ +G(d,p), 6-311(2d,2p), 6-311+ +G(2d,2p), and aug-cc-pVDZ), and three solvation models (SMD, PCM, and CPCM) for an accurate sulfachloropyridazine (SCR) pKa determination It was found that the smallest deviation (0.02 unit of pKa) between the current study and exptl. result was achieved with the BLYP/6-311 + G(d,p)/PCM combination. Therefore, this combination was extended to calculate the pKa of six SCR similar mols. selected through the eletroshape similarity method. For all these mols., the difference between the obtained results and exptl. data ranged between 0.14 and 0.69 units of pKa. This feature suggests that the obtained combination can determine pKa with exptl. precision for complexes that are formed by sulfonamide functional group (SO2NHR). The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Computed Properties of 144-80-9

The Article related to sulfonamide dissociation constant deprotonation substituent effect, acid dissociation constant (pka), dft, electroshape similarity, sulfonamide molecules, Physical Organic Chemistry: Theoretical Organic Chemical Concepts, Including Quantum and Molecular Mechanical Studies and other aspects.Computed Properties of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Kai; Tang, Jing; He, Yang; Guo, Jianmin; Li, Laicai published an article in 2021, the title of the article was Theoretical study on the adsorption and catalytic degradation mechanism of sulfacetamide on anatase TiO2(001) and (101) surfaces.Application of 144-80-9 And the article contains the following content:

D. functional theory (DFT) calculations are used to explore the adsorption characteristics and degradation mechanism of sulfacetamide on anatase TiO2(101) and (001) surfaces. The most probable adsorption configuration was firstly determined by comparing the adsorption energies and structural bond lengths before and after adsorption. After adsorption, some of the bond lengths are elongated. We have proposed about six possible degradation pathways of sulfacetamide, such as branch chain breaking, benzene ring dihydroxylation, amino substitution and sulfur nitrogen bond breaking. And the relevant degradation processes are studied in detail. Based on the calculated results, we conclude that the TiO2(001) surface is more suitable for the degradation of sulfacetamide considering its much smaller energy barriers in several degradation paths than the TiO2(101). Among all the six possible degradation paths, we find that the hydroxyl radical attacks of C(1), C(3) and N(6) atoms of the (001) surface and the C(4) atom of (101) surface sulfacetamide are most probable reaction pathways due to their much smaller energy barriers, i.e. 7.7, 26.1 kcal mol-1 and 14.6, 23.4 kcal mol-1 indicating that these reactions can easily take place in room temperature Our computational results are not only consistent with the exptl. results of sulfacetamide degradation, but also reveal the possible microscopic mechanisms of the photocatalytic reaction. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application of 144-80-9

The Article related to sulfacetamide anatase titania adsorption catalytic degradation mechanism, Physical Organic Chemistry: Theoretical Organic Chemical Concepts, Including Quantum and Molecular Mechanical Studies and other aspects.Application of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics