Category: 144-80-9

On August 16, 2021, Ji, Baocheng; Zhao, Wenhao; Xu, Xu; Han, Yu; Jie, Mingsha; Xu, Gaigai; Bai, Yanhong published an article.Reference of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Development of a modified quick, easy, cheap, effective, rugged, and safe method based on melamine sponge for multi-residue analysis of veterinary drugs in milks by ultra-performance liquid chromatography tandem mass spectrometry. And the article contained the following:

The purpose of this study was to develop a modified QuEChERS method based on melamine sponge for rapid determination of multi-class veterinary drugs in milks by UPLC-MS/MS. Through simple infiltration and extrusion, fast and convenient matrix purification could be achieved within several seconds, and there was no need of extra phase separation operations. Good linearity with correlation coefficient (R2) ≥0.999 was obtained for all drugs in the range of 2∼500μg·kg-1. The obtained matrix effects were within ±20% for all monitored drugs. The recoveries of all monitored drugs ranged from 60.7% to 116.0% at three spiked levels (50, 100, and 200μg·kg-1), with relative standard deviations less than 7.4%. Comparatively low LODs and LOQs were obtained in the ranges of 0.1∼3.8μg·kg-1 and 0.2∼6.3μg·kg-1, resp. Compared with conventional purification adsorbents, melamine sponge yielded an equal or higher purification performance with matrix removal rate as high as 52.5% and acceptable recoveries in range of 60%-120% for all monitored drugs. The satisfactory results have demonstrated the good potential of melamine sponge in matrix purification for rapid determination of multiclass residues in food safety. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Reference of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to milk veterinary drug melamine sponge uplc ms, matrix purification, melamine sponge, milk, quechers, veterinary drug, Food and Feed Chemistry: Analysis and other aspects.Reference of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 31, 2021, Wang, Chun; Chen, Meng; Hu, Qi; Bai, Hua; Wang, Changhai; Ma, Qiang published an article.SDS of cas: 144-80-9 The title of the article was Non-lethal microsampling and rapid identification of multi-residue veterinary drugs in aquacultured fish by direct analysis in real time coupled with quadrupole-Orbitrap high-resolution mass spectrometry. And the article contained the following:

An anal. protocol for the identification of 52 multi-class veterinary drug residues in aquacultured fish has been developed based on direct anal. in real time (DART) coupled with quadrupole-Orbitrap high-resolution mass spectrometry (Q-Orbitrap HRMS). A “sample-and-release” strategy was adopted where live fishes are captured for non-lethal blood microsampling and then released back into the original farming water. A simple micro liquid-liquid extraction (micro-LLE) was incorporated for the extraction and clean-up of veterinary drug analytes from fish blood samples. The main parameters affecting micro-LLE, DART ionization, and Q-Orbitrap HRMS anal. were systematically studied. Data acquisition was carried out using a synchronous full-scan MS/data-dependent MS/MS (full-scan MS1/dd-MS2) workflow. Suspect screening was conducted by comparing the exptl. measured exact mass of precursor and fragment ions with the custom accurate-mass database and by matching the acquired mass spectra against the mass spectral library. The anal. performance of the developed methodol. was assessed in terms of sensitivity, linearity, repeatability, and recovery. The limits of detection (LODs) and quantitation (LOQs) of the 52 analytes were in the range of 0.5-20μg/L and 2-50μg/L, resp. The matrix effect ratios ranged from -23.5% to 25.9%. The developed approach demonstrated promising potential for rapid, real-time monitoring of veterinary drug residues to ensure food safety and consumer health. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).SDS of cas: 144-80-9

The Article related to nonlethal microsampling multiresidue veterinary drug aquacultured fish qorbitrap hrms, Food and Feed Chemistry: Analysis and other aspects.SDS of cas: 144-80-9

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 30, 2021, Yazdanfar, Najmeh; Shamsipur, Mojtaba; Ghambarian, Mahnaz published an article.HPLC of Formula: 144-80-9 The title of the article was Determination of sulfonamide residues in animal foodstuffs by magnetic dispersive solid-phase extraction using magnetic carbon nanocomposites coupled with ion pair-dispersive liquid-liquid micro-extraction combined with HPLC-DAD. And the article contained the following:

Abstract: In this study, magnetic-dispersive solid-phase extraction coupled with ion pair-dispersive liquid-liquid micro-extraction (MSPE-i-DLLME) was used to the pre-concentration and extraction of five sulfonamides residues (sulfadiazine, sulfathiazole, sulfacetamide, sulfamethazine and sulfamethoxazole) in animal foodstuffs. The sulfonamides are extracted using magnetic carbon nanocomposite and then eluted with acetonitrile. In the DLLME step, the target analytes are collected in 1-octanol containing 10% Aliquat-336 (as extraction solvent). Finally, the compounds are quantified by HPLC with DAD detection. The extraction parameters optimized using the one at the time and central composite design methods. Under the optimized conditions: sample solution volume was 100 mL; initial pH: 12, amounts of MCNs: 30 mg; desorption solvent (ACN) volume, 1 mL; desorption condition, 10 min sonication at two step; extraction solvent (1-octanol + 10% aliquat) volume, 115μL; pH of DLLME step, 3; salt effect, 24.6%, (w/v) NaCl; centrifuge, 5 min, 4000 rpm. In these extraction conditions, the proposed procedure represented good pre-concentration factors between 130 and 490; detection limits in the range from 0.01 to 5μg kg-1 (at S/N = 3), and linear response in the 0.1-400μg kg-1 concentration range. The method is successfully applied to the determination of sulfonamides residues in animal foodstuffs. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).HPLC of Formula: 144-80-9

The Article related to sulfonamide residue foodstuff mspe i dllme mcn hplc dad, Food and Feed Chemistry: Analysis and other aspects.HPLC of Formula: 144-80-9

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 31, 2022, Igualada, Carmen; Giraldo, Jennifer; Font, Guillermina; Yusa, Vicent published an article.Computed Properties of 144-80-9 The title of the article was Validation of a multi-residue UHPLC-HRMS method for antibiotics screening in milk, fresh cheese, and whey. And the article contained the following:

The aim of this study was to develop a UHPLC-HRMS methodol. as a suitable tool for the screening of antibiotics in milk, fresh cheese, and whey. Compounds were analyzed using an Orbitrap Exactive analyzer working at a resolving power of 50,000 FWHM in full scan, both in pos. and neg. electrospray ionization mode, and a high mass accuracy (<5 ppm) and a retention time deviation of ±2.5% were set as identification criteria. The multiclass method was developed for the simultaneous determination of 36 substances from different antibiotic groups (β-lactams, lincosamides, macrolides, quinolones, sulfonamides, and tetracyclines) and the quantification was performed by using matrix-matched calibration curves corrected by the corresponding internal standards Matrix effect and recovery percentages were also calculated prior to the selection of internal standard After comparing different sample preparation procedures, a quick and easy extraction with acetate buffer at pH 5.2 and acetonitrile (20/80, volume/volume), followed by C18 dispersive Solid Phase Extraction (dSPE) bulk sorbent was selected. The detection capabilities (CCβs) were established at 25% or 50% of the Maximum Residue Limit (MRL) set in milk (no regulation for cheese and whey), and precision (repeatability and reproducibility) and trueness (recovery) were satisfactory according to Commission Decision 2002/657/EC. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Computed Properties of 144-80-9

The Article related to antibiotics milk fresh cheese whey uhplchrms, Food and Feed Chemistry: Analysis and other aspects.Computed Properties of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 15, 2022, Sun, Feifei; Tan, Haiguang; Abdallah, Mohamed F.; Li, Yanshen; Zhou, Jinhui; Li, Yi; Yang, Shupeng published an article.Name: N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was A novel calibration strategy based on isotopic distribution for high-throughput quantitative analysis of pesticides and veterinary drugs using LC-HRMS. And the article contained the following:

Preparation of calibration curves is a critical step for large-scale quantification. However, this procedure is time-consuming, labor intensive. Herein, a novel isotopologue multipoint calibration (IMC) strategy, was proposed and demonstrated for the simultaneous quantitation of 120 pesticides and 83 veterinary drugs in surface water samples using Liquid Chromatog.-High Resolution Mass Spectrometry (LC-HRMS). In this strategy, the natural isotopic distribution was used to generate external calibration curves, eliminating the need of analyst’s adjustment and many sets of chem. standard solutions required in external calibration curves. Addnl., this strategy was comprehensively validated, and the results indicated this strategy had better performance in both accuracy and precision, fully meeting the requirements for the quant. anal. Interestingly, for the samples with high concentration beyond the upper limit of quantitation, the IMC strategy could avoid samples dilution by monitoring the less abundant isotopic channels. Furthermore, the IMC method was successfully applied in the surface water samples collected from Anhui province, China. Among which, sulfamethoxazole and imidacoprid were the main contributors. In conclusion, we present a promising LC-HRMS strategy for the accurate quantitation of small mols., which has a potential application in food and environmental anal. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Name: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to pesticide veterinary drug isotopic distribution calibration, high resolution mass spectrometry, isotope distribution, quantitative analysis, water environment pollution, Waste Treatment and Disposal: Other and other aspects.Name: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 30, 2022, Ruan, Weifeng; Wang, Jiaxi; Huang, Jie; Tai, Yiping; Wang, Rui; Zhu, Weipeng; Yang, Yang published an article.HPLC of Formula: 144-80-9 The title of the article was The in vivo and vitro degradation of sulfonamides in wetland plants reducing phytotoxicity and environmental pollution. And the article contained the following:

Aquatic plants can be used for in situ remediation of water-borne pharmaceutical compounds; however, such information and that of the potential risks of metabolites released into the environment are limited. This study determined the capacity of Canna indica and Acorus calamus used in the remediation of water-borne sulfonamides (SA). The tolerance, removal, accumulation, and biotransformation of various water-borne SAs were investigated in vivo by exposing plants to SA solutions (50 μg/L and 500 μg/L). After 28 days, C. indica removed more SAs (89.3-97.8%) than A. calamus (12.8-84.6%) and non-planted systems (8.0-69.3%). The SA removal results, except from the A. calamus system with 500 μg/L SA, fit the first-order kinetics model. The estimated half-lives of all SAs were 3-40 h and 2-60 h in the C. indica and A. calamus systems, resp. In vivo biotransformation and rhizosphere degradation were the major phyto-removal mechanisms, constituting 24.9-81.1% and 0.0-37.1% of all SAs in the C. indica and A. calamus systems, resp. SA acetyl metabolites were detected only in plant tissues supporting evidence for plant metabolic processes without risk into the environment. SA metabolism including oxidation, methylation, and conjugation via acetylation was potentially beneficial to accumulation and tolerate stress of antibiotic. Canna indica was more suitable for cleaning SA. Our findings better clarify the potential and low risks of phytoremediation in antibiotic-contaminated waters. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).HPLC of Formula: 144-80-9

The Article related to sulfonamide wetland phytotoxicity biol wastewater treatment, aquatic pollution, detoxification, environmental risk, metabolism in vivo, phytoremediation, Placeholder for records without volume info and other aspects.HPLC of Formula: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 15, 2021, Kong, Ming; Bu, Yuan-Qing; Zhang, Qin; Zhang, Sheng-Hu; Xing, Li-Qun; Gao, Zhan-Qi; Bi, Feng-Zhi; Hu, Guan-Jiu published an article.HPLC of Formula: 144-80-9 The title of the article was Distribution, abundance, and risk assessment of selected antibiotics in a shallow freshwater body used for drinking water, China. And the article contained the following:

With rapid improvements in industrialization and urbanization, antibiotics are now extensively used to prevent and treat human and animal diseases and husbandry and aquaculture. Some research has been conducted to assess the environmental distribution and risk level of antibiotics, but their distribution remains largely uncharacterized. Thus, this study investigated the distribution and abundance of 39 antibiotics belonging to five groups, and their associated risks in surface water around Luoma Lake in the north of Jiangsu province, China. Nineteen antibiotics were detected, at a detection frequency (DF) ranging from 2.27% to 100%. The total antibiotics (ΣABs) concentrations ranged from 34.91 to 825.93 ng/L, with a median concentration of 195.45 ng/L. Among these antibiotics, chlortetracycline (DF: 100%; median: 172.02 ng/L) was the dominant antibiotic, accounting for a median percentage of 91.0% of ΣABs concentrations Spearman rank correlation method found a significant correlation between clindamycin (DF: 72.7%; median: 2.01 ng/L) and lincomycin (DF: 79.5%; median: 4.58 ng/L). The ecol. risk quotient (RQ) values for two out of 44 sampling sites were higher than 1, indicating a high risk; 11.4% of the RQ values fell between 0.1 and 1, indicating a medium risk. Moreover, roxithromycin was found to be the dominant contributor to the ecol. risk, accounting for a median of 79.7% of ΣABs. However, the total non-carcinogenic (<6.54 x 10-4) and carcinogenic risks (<1.64 x 10-7) of ΣABs were negligible at the detected concentrations The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).HPLC of Formula: 144-80-9

The Article related to antibiotics drinking water shallow freshwater risk assessment china, antibiotic residues, ecological risk, health risk, luoma lake, spatial distribution, Placeholder for records without volume info and other aspects.HPLC of Formula: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 15, 2022, Matamoros, V.; Casas, M. Escola; Mansilla, S.; Tadic, Dj.; Canameras, N.; Carazo, N.; Portugal, J.; Pina, B.; Diez, S.; Bayona, J. M. published an article.HPLC of Formula: 144-80-9 The title of the article was Occurrence of antibiotics in Lettuce (Lactuca sativa L.) and Radish (Raphanus sativus L.) following organic soil fertilisation under plot-scale conditions: Crop and human health implications. And the article contained the following:

Recent studies have demonstrated the crop uptake of antibiotics (ABs) from soils treated with AB-carrying fertilisers. However, there is a lack of plot-scale studies linking their effects at the agronomic and metabolomic/transcriptomic level to their impact on human health. This paper assesses the plant uptake of 23 ABs following two productive cycles of lettuce and radish cropped with sewage sludge, pig slurry, the organic fraction of municipal solid waste, or chem. fertilisation under plot-scale conditions (32 plots spanning 3-10 m2 each). AB uptake by plants depended on both the vegetable and the AB class and was higher in radish than in lettuce edible parts. Levels ranged from undetectable to up to 76 ng/g (fresh weight). Repetitive organic fertilisation resulted in an increase in the concentration of ABs in lettuce leaves, but not in radish roots. Significant metabolomic and transcriptomic changes were observed following soil fertilisation. Nevertheless, a human health risk assessment indicates that the occurrence of ABs in lettuce or radish edible parts does not pose any risk. To our knowledge, this is the first holistic plot-scale study demonstrating that the use of organic fertilisers containing ABs is safe for crop security and human health. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).HPLC of Formula: 144-80-9

The Article related to lettuce radish organic soil fertilization antibiotic occurrence health implication, antibiotics, crops, human health risk, metabolomics, transcriptomics, Placeholder for records without volume info and other aspects.HPLC of Formula: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 20, 2022, Wang, Yu-Qing; Hu, Li-Xin; Zhao, Jia-Hui; Han, Yu; Liu, You-Sheng; Zhao, Jian-Liang; Yang, Bin; Ying, Guang-Guo published an article.Reference of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Suspect, non-target and target screening of pharmaceuticals and personal care products (PPCPs) in a drinking water system. And the article contained the following:

Drinking water quality and safety are very important in protecting human health. Chem. contaminants in drinking water system have become an increasing concern. Our knowledge about what chems. are present in drinking water is still limited. Here we screened chems. of emerging concern in a conventional drinking water system based on suspect, non-target screening and target anal., and assessed their variations in different seasons and different treatment units. Overall, 720 chems. were identified with HRMS databases from the suspect and non-target screening and 48 chems. in five categories were further confirmed with the high confidence level, with predominance of pharmaceuticals and personal care products (PPCPs) and pesticides. Four compounds are newly found in aquatic environment with no literature or chem. occurrence data record. Temporal variations and variable removals were observed for these chems. in the system. Target anal. of 110 PPCPs showed detection of 21, 19 and 22 compounds in the drinking water treatment plant with a concentration range of 0.11-844 ng/L in the three seasons, but only 8, 9 and 15 compounds detected in tap water (0.16-32.5 ng/L). The variations of the detected chems. were less obvious in tap water, with most having concentrations below 2 ng/L. The results indicated efficient removal for most PPCPs in the drinking water system. The findings from this study demonstrated the strong capability of combined non-target screening and target anal. in identifying and assessing various organic chems. in drinking water system. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Reference of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to pharmaceutical personal care product detection drinking water system, drinking water, emerging contaminants, suspect screening, target analysis, water, Placeholder for records without volume info and other aspects.Reference of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 2, 2022, Song, Xue-Chao; Dreolin, Nicola; Damiani, Tito; Canellas, Elena; Nerin, Cristina published an article.Safety of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Prediction of Collision Cross Section Values: Application to Non-Intentionally Added Substance Identification in Food Contact Materials. And the article contained the following:

The synthetic chems. in food contact materials can migrate into food and endanger human health. In this study, the traveling wave collision cross section in nitrogen values of more than 400 chems. in food contact materials were exptl. derived by traveling wave ion mobility spectrometry. A support vector machine-based collision cross section (CCS) prediction model was developed based on CCS values of food contact chems. and a series of mol. descriptors. More than 92% of protonated and 81% of sodiated adducts showed a relative deviation below 5%. Median relative errors for protonated and sodiated mols. were 1.50 and 1.82%, resp. The model was then applied to the structural annotation of oligomers migrating from polyamide adhesives. The identification confidence of 11 oligomers was improved by the direct comparison of the exptl. data with the predicted CCS values. Finally, the challenges and opportunities of current machine-learning models on CCS prediction were also discussed. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Safety of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to nonintentional substance food contact collision crossection svm, nias, collision cross section, food contact materials, ion mobility, machine learning, Placeholder for records without volume info and other aspects.Safety of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics