Category: 144-80-9

On May 31, 2022, Konda, Satyanand; Asati, Ankita; Williams, Mike; Mudiam, Mohana Krishna Reddy published an article.Electric Literature of 144-80-9 The title of the article was Development and evaluation of a multi-class analytical method based on solid-phase extraction combined with liquid chromatography-tandem mass spectrometry for the analysis of pharmaceuticals and personal care products in urban wastewater samples. And the article contained the following:

An anal. method has been developed for the quant. evaluation of 64 pharmaceuticals and personal care products in urban wastewater using solid-phase extraction coupled with liquid chromatog.-tandem mass spectrometry. Design of experiments approach was used in the multiparametric optimization of solid-phase extraction method for the anal. of pharmaceuticals and personal care products. The method was found to be linear within the range of 0.01-1 渭g/L with coefficient of determination (R2) ranging from 0.990 to 0.999. The limit of detection and limit of quantification were found to be in the range of 0.002-0.028 and 0.007-0.091 渭g/L, resp. The accuracy was calculated with respect to percent recovery, and it was found to be in the range of 70.0-129% for all the analytes. The intra- and interday precisions were found to be less than 15% relative standard deviation for all the analytes. The developed anal. method was applied to real samples collected from four different sampling sites of Musi River in Hyderabad to evaluate its performance. The method found a wide application for the anal. of urban wastewater samples. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Electric Literature of 144-80-9

The Article related to wastewater analysis pharmaceutical personal care product solid phase extraction, Placeholder for records without volume info and other aspects.Electric Literature of 144-80-9

Referemce:
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Amide – an overview | ScienceDirect Topics

Zheng, Guihua; Yang, Yiyi; Deng, Linghui; Zhang, Ting; Zhu, Feiyun; Sun, Jing; Li, Shuangjiang; Feng, Xiaonan published an article in 2022, the title of the article was Pollution status and health impact assessment of antibiotics in environmental – and drinking water.Electric Literature of 144-80-9 And the article contains the following content:

The problem of antibiotics pollution in environmental water and drinking water has attracted the attention of environmental protection departments and all walks of life. At present, antibiotics have been widely detected in many water systems, and the concentration range is from ng/L to pg/L. In this paper, a method for the anal. of antibiotics in water by high performance liquid chromatog. tandem mass spectrometry (HPLC-MS/MS) was established. Then, the risk quotient (HQ) of antibiotics in wastewater treatment plant effluent and river water was calculated and studied. The results showed that some antibiotics did not cause direct ecol. risk. Finally, the health risk assessment of environmental water and drinking water was carried out. The results showed that the non carcinogenic risk caused by antibiotic pollution in the reservoir was far lower than the acceptable risk level, even far lower than the negligible risk level, indicating that the residues of these antibiotics in the drinking water would not pose significant non carcinogenic harm to human body. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Electric Literature of 144-80-9

The Article related to antibiotic wastewater treatment plant drinking water health risk assessment, Placeholder for records without volume info and other aspects.Electric Literature of 144-80-9

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wu, Huizhen; Zhou, Min; Xu, Jie; Wang, Jianmei; Tong, Jianying; Sun, Nabo; Qian, Mingrong published an article in 2022, the title of the article was Determining a wide range of antibiotics and pesticides in poultry feathers using selective accelerated solvent extraction-liquid chromatography-mass spectrometry.SDS of cas: 144-80-9 And the article contains the following content:

This study established a detection method based on accelerated solvent extraction-liquid chromatog.-mass spectrometry for determining residues of 3 chloramphenicols, 8 macrolides, 18 sulfonamides, 4 nitroimidazoles, 15 insecticides, and 22 fungicides in poultry feathers. The extraction solvent, methanol, was used for a static extraction time of 5 min, and repeated three times. Fifty milligrams of adsorbents C18/PSA (1 : 1, W/W) were added to the extraction cell to achieve simultaneous extraction and purification The extraction efficiency of three solvents, methanol, acetonitrile and Et acetate, was investigated. An orthogonal exptl. design was used to explore the optimal combination of extraction temperature, static extraction time, number of extraction cycles, and adsorbent ratio for accelerated solvent extraction After the optimal ratio was determined, the dosage of adsorbents was optimized. The extracted sample solution was concentrated by blowing nitrogen, redissolved, passed through a 0.22 渭m PTFE membrane filter, then injected for instrumental anal. The validation results showed that the recovery of the proposed method was 60.4-107.6%, the limit of detection 0.2-3.0 渭g kg-1, and the limit of quantification 0.5-8.3 渭g kg-1. This quant. multi-residue detection method was able to determine the residues of 70 target compounds in poultry feathers. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).SDS of cas: 144-80-9

The Article related to liquid chromatog mass spectrometry antibiotic pesticide poultry feather, Placeholder for records without volume info and other aspects.SDS of cas: 144-80-9

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On November 15, 2022, Zhang, Keqiang; Ruan, Rong; Zhang, Zulin; Zhi, Suli published an article.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was An exhaustive investigation on antibiotics contamination from livestock farms within sensitive reservoir water area: Spatial density, source apportionment and risk assessment. And the article contained the following:

Although the studies on antibiotic contamination are common at present, large-scale sampling studies drawing highly representative conclusions are still scarce. This study conducted a comprehensive investigation on a total of 1183 samples from 70 livestock farms within a sensitive area around reservoir waters. 45 types of antibiotics belonging to 5 different classes were monitored. This is the first anal. to comprehensively investigate the d. distribution, source apportionment, ecol. and health risk of antibiotics in an entire area of sensitive waters. The results showed that the layer manure samples had highest detection rate of antibiotics (0.0 %-96.1 %, average value = 30.7 %) followed by pig manure samples. Oxytetracycline had the highest concentration of 712.16 mg/kg in a pig manure sample. Different from using antibiotic concentration as a proxy for pollution level, the spatial d. was calculated by averaging antibiotic concentration to area and converting different livestock to pig equivalent The spatial d. of pig equivalent can more realistically reflect the pollution caused by different breeds of livestocks. It was shown that the pig farms contributed higher to total antibiotic d. than the layer and cattle farms did. After assessed, a few antibiotics (oxytetracycline, chlorotetracycline and tetracycline) have posed high ecol. risks to soil around the farms. However, none of them caused hazard quotient (HQ) risk and carcinogenic risk (CR) to human health in the water of reservoir. Children were more likely to be at hazard risk than adults. Antibiotic mass fluctuation rules were analyzed along the chain (feed 鈫?livestock waste 鈫?soil 鈫?surface water). Feed, livestock waste and soil had similar diversity, but the antibiotic concentrations continued to decline, implying the possible sources of antibiotic residues were similar. Thus, it is important to reduce unnecessary antibiotic use to prevent the potential long-term risk of antibiotics. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotic livestock farm risk assessment surface water, antibiotic, livestock farm, risk assessment, source apportionment, spatial density, Placeholder for records without volume info and other aspects.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 15, 2022, Tan, Haiguang; Sun, Feifei; Abdallah, Mohamed F.; Li, Jianxun; Zhou, Jinhui; Li, Yi; Yang, Shupeng published an article.Category: amides-buliding-blocks The title of the article was Background ions into exclusion list: A new strategy to enhance the efficiency of DDA data collection for high-throughput screening of chemical contaminations in food. And the article contained the following:

Foods contaminated with hazardous compounds, could pose potential risks for human health. To date, there is still a big challenge in accurate identification. In this study, a novel data-dependent acquisition (DDA) approach, based on a combination of inclusion list and exclusion list, was proposed to acquire more effective MS/MS spectra. This strategy was successfully applied in a large-scale screening survey to detect 50 mycotoxins in oats, 155 veterinary drugs in dairy milk, and 200 pesticides in tomatoes. Compared with traditional acquisition modes, this new strategy has higher detection rate, particularly at ultra-low concentration by eliminating background influence, thereby generating the MS/MS spectra for more potential hazardous materials instead of matrix interference. Addnl., the obtained MS/MS spectra are simpler and more likely to be traced back than DIA. Moreover, this new strategy would be more comprehensively applied in food safety monitoring with the improvement of HRMS and post-acquisition techniques. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Category: amides-buliding-blocks

The Article related to throughput screening chem contamination food, data acquisition, food safety, high-resolution mass spectrometer, non-targeted screening, Placeholder for records without volume info and other aspects.Category: amides-buliding-blocks

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Amide – an overview | ScienceDirect Topics

On February 5, 2021, Song, Mengke; Song, Dandan; Jiang, Longfei; Zhang, Dayi; Sun, Yingtao; Chen, Guoen; Xu, Huijuan; Mei, Weiping; Li, Yongtao; Luo, Chunling; Zhang, Gan published an article.Synthetic Route of 144-80-9 The title of the article was Large-scale biogeographical patterns of antibiotic resistome in the forest soils across China. And the article contained the following:

Soil is a reservoir of environmental resistomes. Information about their distribution, profiles, and driving forces in undisturbed environments is essential for understanding and managing modern antibiotic resistance genes (ARGs) in human disturbed environments. However, knowledge about the resistomes in pristine soils is limited, particularly at national scale. Here, we conducted a national-scale investigation of soil resistomes in pristine forests across China. Although the antibiotics content was low and ranged from below limit of detection (LOD) to 0.290 渭g/kg, numerous detected ARGs conferring resistance to major classes of modern antibiotics were identified and indicated forest soils as a potential source of resistance traits. ARGs ranged from 6.20 x 10-7 to 2.52 x 10-3 copies/16S-rRNA and were predominated by those resisting aminoglycoside and encoding deactivation mechanisms. Low abundance of mobile genetic elements (MGEs) and its scarcely pos. connections with ARGs suggest the low potential of horizontal gene transfer. The geog. patterns of ARGs and ARG-hosts in pristine forest soils were mainly driven by soil physiochem. variables and followed a distance-decay relationship. This work focusing on pristine soils can provide valuably new information for our understanding of the ARGs in human disturbed environments. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Synthetic Route of 144-80-9

The Article related to gene expression antibiotic resistance forest soil, antibiotic resistome, distribution, driving force, forest soils, national scale, Placeholder for records without volume info and other aspects.Synthetic Route of 144-80-9

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On October 31, 2022, Gao, Hui; Zhao, Fuqiang; Li, Ruijing; Jin, Shuaichen; Zhang, Haibo; Zhang, Keyu; Li, Shisheng; Shu, Qin; Na, Guangshui published an article.COA of Formula: C8H10N2O3S The title of the article was Occurrence and distribution of antibiotics and antibiotic resistance genes in water of Liaohe River Basin, China. And the article contained the following:

Surface water environment is an important repository of antibiotics and antibiotic resistance genes (ARGs). It is of great significance to study the occurrence and distribution of antibiotics and ARGs in surface water environment. In this study, the Liaohe River Basin, China was taken as the study area, and the concentrations of antibiotics and ARGs in water were investigated by HPLC-MS/MS and HT-qPCR. The results showed that a total of 53 antibiotics of 6 types were detected in water, and the pollution level was at ND∼331.64 ng/L, where PCG was the highest. Totally 164 ARGs and 10 mobile genetic elements (MGEs) were detected in the water, and the absolute abundances were at 2.18 × 104∼3.95 × 107 copies/L and 1.82 × 105-3.78 × 107 copies/L, resp. The multidrug and aminoglycoside were the dominant ARG types. Amoxicillin, erythromycin, anhydroerythromycin and ofloxacin posed certain ecol. risks for sensitive aquatic organisms. In spatial distribution, the pollution of antibiotics and ARGs in the Daliao River system was higher than that in the Liaohe River system. There was a significant pos. correlation between total concentrations of antibiotics and total relative abundance of ARGs (r = 0.66, p < 0.05). The co-occurrence of multiple antibiotics promoted the pollution and spread of ARGs. In addition, the total relative abundance of MGEs and ARGs showed a significant pos. correlation (r = 0.946, p < 0.01), and MGEs played an important role in the occurrence and evolution of ARGs in water. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).COA of Formula: C8H10N2O3S

The Article related to antibiotic resistance gene occurrence distribution water hplc ms, Water: Analysis and other aspects.COA of Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 31, 2021, Low, Kyleyoung; Chai, Layching; Lee, Choonweng; Zhang, Gan; Zhang, Ruijie; Vahab, Vaezzadeh; Bong, Chuiwei published an article.Formula: C8H10N2O3S The title of the article was Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak. And the article contained the following:

Abstract: Antibiotics released into the environment through anthropogenic activities exert selective pressure, driving bacteria towards increasing antimicrobial resistance. The prevalence of antibiotics and the ecol. risks posed in the riverine estuarine of Larut River and Sangga Besar River, which included wastewater effluents from hospital, zoo, and poultry slaughterhouse sources were investigated. Solid phase extraction (SPE) followed by high-performance liquid chromatog. tandem mass chromatog. (HPLC-MS/MS) were used to extract and quantify the antibiotic residues from 22 antibiotics belonging to six major antibiotic classes (sulfonamide, macrolide, fluoroquinolone, phenicol, trimethoprim, and tetracycline). Sixteen antibiotic residues were detected with concentrations ranging from limit of detection (LOD) to 1 262.3 ng/L. Fluoroquinolones and macrolides were the most frequently detected compounds Erythromycin, clarithromycin, and ofloxacin detected in hospital and zoo effluents posed a high risk to algae while tetracycline had low to medium ecol. risks toward all the relevant organisms from aquatic environments (algae, invertebrate Daphnia magna, and fish). The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Formula: C8H10N2O3S

The Article related to antibiotic risk assessment riverine estuarine water perak, Water: Analysis and other aspects.Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Guo, Yaoguang; Liu, Zhiyuan; Lou, Xiaoyi; Fang, Changling; Wang, Pu; Wu, Genying; Guan, Jie published an article in 2021, the title of the article was Insights into antimicrobial agent sulfacetamide transformation during chlorination disinfection process in aquaculture water.Name: N-((4-Aminophenyl)sulfonyl)acetamide And the article contains the following content:

Antibiotic addition and chlorination are two common processes in fishery culture. Antibiotic residues not only pollute aquaculture water, but are also one of the potential precursors of disinfection byproducts (DBPs) during chlorination. The degradation kinetics, products identification and reaction mechanism of sulfacetamide (SFA), a new sulfonamides antibiotics, and potential formation of haloacetic acids (HAAs) in chlorination were explored. The results showed that the degradation of SFA followed pseudo first-order kinetic model, and chlorinating agent dose, pH of water, water temperature, NH4+, HCO3- and humic acid (HA) had various effects on the degradation of SFA and the yields of HAAs. The presence of Br- accelerated both the degradation rate of SFA and more formation of Br-DBPs. Through the identification of intermediate products, we proposed the transformation pathway of SFA during the chlorination disinfection process. Namely, in this NaClO disinfection system, the C-S bond between the sulfonyl group and benzene ring, and S-N bond between sulfonyl and acylamino of SFA were broken, and then the primary formed groups were further oxidized to produce intermediates, such as chloroanilines and chlorophenols. And then chlorophenols were subsequently chlorinated to form toxic HAAs. The present study might be of significance for the evaluation of effective degradation of SFA and potential production of halogenate-DBPs (H-DBPs) during the chlorination disinfection process in aquaculture water. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Name: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to sulfacetamide chlorination disinfection degradation, Water: Analysis and other aspects.Name: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Liu, Xi; Zhang, Zhi; Zhang, Lu; Fan, Weiying; Yang, Chao; Li, Enhua; Du, Yun; Wang, Xuelei published an article in 2021, the title of the article was Inconsistent seasonal variation of antibiotics between surface water and groundwater in the Jianghan Plain: Risks and linkage to land uses.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide And the article contains the following content:

Antibiotics are widely used in humans and animals, but their transformation from surface water to groundwater and the impact of land uses on them remain unclear. In this study, 14 antibiotics were systematically surveyed in a complex agricultural area in Central China. Results indicated that the selected antibiotic concentrations in surface waters were higher in winter (average: 32.7 ng/L) than in summer (average: 17.9 ng/L), while the seasonal variation in groundwaters showed an opposite trend (2.2 ng/L in dry winter vs.8.0 ng/L in summer). Macrolides were the predominant antibiotics in this area, with a detected frequency of over 90%. A significant correlation between surface water and groundwater antibiotics was only observed in winter (R2=0.58). This study further confirmed the impact of land uses on these contaminants, with optimal buffer radii of 2500 m in winter and 500 m in summer. Risk assessment indicated that clarithromycin posed high risks in this area. Overall, this study identified the spatiotemporal variability of antibiotics in a typical agricultural area in Central China and revealed the impact of land uses on antibiotic pollution in aquatic environments. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotic surface water groundwater, antibiotic pollution, honghu lake, land use, optimal buffer, risk assessment, antibiotics, environmental risk assessment, groundwaters, nitrates role: pol (pollutant), occu (occurrence), ph, redox potential, surface waters, temperature, turbidity and other aspects.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
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Amide – an overview | ScienceDirect Topics