Category: 14294-10-1

Kolodziuk, Robert published the artcilePalladium-catalyzed Suzuki cross-coupling of aryl halides with aryl boronic acids in the presence of glucosamine-based phosphines, Computed Properties of 14294-10-1, the publication is Journal of Organometallic Chemistry (2003), 687(2), 384-391, database is CAplus.

Carbohydrate-substituted phosphines are easily obtained in quite good yields by coupling of protected or non-protected D-glucosamine with the corresponding diphenylphosphino acid. These neutral ligands, in association with palladium acetate, are very active catalysts in the Suzuki cross-coupling reaction. The polyhydroxy phosphines are more active than the peracetylated phosphines. The process tolerates electron-rich as well as electron-poor substituents. Excellent turnovers, up to 97 000 are observed

Journal of Organometallic Chemistry published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, Computed Properties of 14294-10-1.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Umape, Prashant G. published the artcileSynthesis and characterization of novel yellow azo dyes from 2-morpholin-4-yl-1,3-thiazol-4(5H)-one and study of their azo-hydrazone tautomerism, Name: Morpholine-4-carbothioamide, the publication is Dyes and Pigments (2013), 99(2), 291-298, database is CAplus.

Novel yellow azo dyes were synthesized by diazotization of aromatic amines followed by coupling with 2-morpholin-4-yl-1,3-thiazol-4(5H)-one and fully characterized. The geometries of the synthesized dyes for azo and hydrazone tautomeric forms were optimized using B3LYP, CAM-B3LYP and M06 functional and 6-31G(d) and 6-311++G (d,p) basis sets, also their electronic excitation properties were evaluated using d. functional theory. The optimized geometries reveal that the hydrazone for is more stable than the azo form. Photophys. properties of the synthesized dyes were evaluated by UV-Visible spectroscopy and compared with computed vertical excitation obtained from TDDFT. The results clearly illustrate existence of dye 8a, 8b and 8c in hydrazone tautomeric form, while 8d exist in both azo as well as hydrazone form. Thermal stabilities were estimated by using thermo gravimetric anal., and results revels that the synthesized dyes have good thermal stability.

Dyes and Pigments published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C20H19NO4, Name: Morpholine-4-carbothioamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Avhad, Kiran C. published the artcileViscosity induced emission of red-emitting NLOphoric coumarin morpholine-thiazole hybrid styryl dyes as FMRs: Consolidated experimental and theoretical approach, Safety of Morpholine-4-carbothioamide, the publication is Optical Materials (Amsterdam, Netherlands) (2018), 90-107, database is CAplus.

Four new coumarin hybrid styryl dyes are synthesized by condensing 4-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)-2-morpholinothiazole-5-carbaldehyde with dicyanovinylene containing active methylene intermediates and their linear and non-linear optical properties are studied. The dye having dicyanovinylene-isophorone acceptor displayed a large Stokes shift of 3702-4795 cm^-1 in non-polar to polar solvent resp. The dyes exhibit a good charge transfer characteristics and pos. emission solvatochromism (∼50 nm-72 nm) in non-polar to a polar solvent which is well supported by multi-linear regression anal. Viscosity induced enhancement study in ethanol/polyethylene glycol-400 system shows 2.71-6.78 fold increase in emission intensity. The intra and twisted-intramol. charge transfer (ICT-TICT) characteristics were established using emission solvatochromism, polarity plots, generalized Mullikan-Hush (GMH) anal. and optimized geometry. A dye having the highest charge transfer dipole moment relatively possess the maximum two-photon absorption cross-section area (KK-1 = 165-207 GM) which was established using theor. two-level model. The NLO properties have been investigated employing solvatochromic and computational methods and were found to be directly proportional to the polarity of the solvent. Z-scan results reveal that the dyes KK-1 and KK-2 possesses reverse saturable kind of behavior whereas KK-3 and KK-4 show saturable kind of behavior. From the exptl. and theor. data, these coumarin thiazole hybrid dyes can be considered as promising candidates for FMR and NLOphores.

Optical Materials (Amsterdam, Netherlands) published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, Safety of Morpholine-4-carbothioamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Griffiths, John published the artcileSynthesis, light absorption and fluorescence properties of new thiazole analogues of the xanthene dyes, Recommanded Product: Morpholine-4-carbothioamide, the publication is Dyes and Pigments (2003), 57(2), 107-114, database is CAplus.

The synthesis of a new class of cationic dye is described, whose chromophoric system is formally related to that of the cationic xanthene dyes in which one of the aminophenyl rings is replaced by a 2-aminothiazole ring. The light absorption and fluorescence properties of a range of representative dyes of this type have been investigated. The dyes were found to absorb at shorter wavelengths than their xanthene analogs (λ_max 490-506 nm in methanol), in agreement with theor. predictions, and they also showed moderate to intense fluorescence in dichloromethane solution, with Stokes shifts ranging from 33 to 50 nm.

Dyes and Pigments published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, Recommanded Product: Morpholine-4-carbothioamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Matulenko, Mark A. published the artcile5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure-activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors, HPLC of Formula: 14294-10-1, the publication is Bioorganic & Medicinal Chemistry (2005), 13(11), 3705-3720, database is CAplus and MEDLINE.

4-Amino-5,7-disubstituted pyridopyrimidines are potent, non-nucleoside inhibitors of adenosine kinase (AK). The authors recently identified a potent, orally efficacious analog I containing a 7-pyridylmorpholine substituted ring system as the key structural element of this template. The pharmacol. effects of five- and six-membered heterocyclic ring replacements for the pyridine ring in I are reported. These replacements were found to have interesting effects on in vivo efficacy and genotoxicity as well as in vitro potency. The authors discovered that the nitrogen in the heterocyclic ring at C(7) is important for the modulation of mutagenic side effects (Ames assay).

Bioorganic & Medicinal Chemistry published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, HPLC of Formula: 14294-10-1.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Kutschy, P. published the artcileReactivity of N’-substituted N-(4-pentynoyl)- and N-[2-(2-propynyl)-4-pentynoyl]thioureas, Category: amides-buliding-blocks, the publication is Chemical Papers (1987), 41(4), 519-26, database is CAplus.

Treatment of HCCCH₂CHRCONHCSNR¹R² (I; R = H, HCCCH₂; R¹, R² = H, Ph; R¹R²N = morpholino) with EtONa and HgCl₂ or Hg(OAc)₂ resp., results in splitting-off the acyl residue and formation of H₂NCSNR¹R². Heating I (R = HCCCH₂, R¹R²N = morpholino) EtOH with a catalytic amount of TiCl₃ gave 58% (HCCCH₂)₂CHCONHCSOEt. Treating I (R = H, HCCCH₂; R¹ = R² = Ph) with Br₂ in CHCl₃ gave 80-87% the benzothiazoline derivatives II (R = H, HCCCH₂).

Chemical Papers published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Katritzky, Alan R. published the artcileSynthesis of mono- and N,N-disubstituted thioureas and N-acylthioureas, SDS of cas: 14294-10-1, the publication is Synthesis (2004), 1799-1805, database is CAplus.

1-Benzotriazole-1-carbothioamide, prepared from 1-cyanobenzotriazole and hydrogen sulfide, reacts with amines to give thioureas R¹NR²CSNH₂ (R¹ = MeOC₆H₄, Bn, pyrrolidinyl, Ph, PhNH; R² = H, Bn). Reactions of (benzotriazol-1-yl)carboximidamides and acyl- or arylaminocarbonyl(benzotriazol-1-yl)carboximidamides with hydrogen sulfide give the corresponding thioureas, N-acylthioureas, or N-carbamoylthioureas.

Synthesis published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, SDS of cas: 14294-10-1.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Keshari, Twinkle published the artcileCarbon tetrabromide mediated oxidative cyclocondensation of ketones and thioureas: an easy access to 2-aminothiazoles, COA of Formula: C5H10N2OS, the publication is Tetrahedron Letters (2015), 56(41), 5623-5627, database is CAplus.

A simple, mild, and efficient one-pot method for the synthesis of substituted 2-aminothiazoles has been reported. The reaction involves the formation of sulfenyl bromide as an umpolung intermediate of nucleophilic sulfur, which is responsible for C-S bond formation leading to oxidative cyclization of ketones and thioureas to furnish the desired products. Carbon tetrabromide was used as a convenient and mild brominating reagent under basic condition at room temperature to give 2-aminothiazoles in good to excellent yields.

Tetrahedron Letters published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C5H10N2OS, COA of Formula: C5H10N2OS.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Solankee, Anjani published the artcile2-Substituted phenyl-5-(ω-methoxycarbonyl propyl/pentyl)-Δ²-thiazolin-4-one. Part IV, HPLC of Formula: 14294-10-1, the publication is Journal of the Institution of Chemists (India) (1994), 66(3), 91-2, database is CAplus.

The title compounds I (R = substituted Ph, 3-pyridyl, morpholino, n = 3, 5) were prepared by treatment of 2-bromoadipic and 2-bromosuberic acid with thioamides followed by esterification of the corresponding acids. with MeOH and thionyl chloride.

Journal of the Institution of Chemists (India) published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C9H8F2O2, HPLC of Formula: 14294-10-1.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Uhlemann, Erhard published the artcileSynthesis of 1,1-disubstituted 3-thiobenzoylthioureas, COA of Formula: C5H10N2OS, the publication is Zeitschrift fuer Chemie (1981), 21(11), 413-14, database is CAplus.

The title thioureas were prepared by acylation of PhCSNH₂ with dialkyl(thio)carbamoyl chlorides in pyridine in the presence of Ni(OAc)₂ (isolated as the Ni chelates), thiobenzoylation of thioureas with PhCS₂CH₂CO₂H in MeCN containing KOH, or treating dialkyl(thio)carbamoyl isothiocyanates with PhMgBr in Et₂O.

Zeitschrift fuer Chemie published new progress about 14294-10-1. 14294-10-1 belongs to amides-buliding-blocks, auxiliary class Morpholine,Thiourea,Amine,Amide, name is Morpholine-4-carbothioamide, and the molecular formula is C8H8ClN5, COA of Formula: C5H10N2OS.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics