Category: 123-39-7

Sikorski, Patryk published the artcileSolid-liquid equilibria in systems consisting of potassium pseudohalides and amides, Recommanded Product: N-Methylformamide, the main research area is potassium pseudohalide amide solid liquid equilibrium.

Within the framework of this research, we measured solid-liquid equilibrium diagrams of binary systems of potassium thiocyanate or potassium selenocyanate in {formamide, or N-methylformamide, or N,N-dimethylformamide} as functions of temperature, using the cloud-point and DSC techniques over the full concentration range. The temperatures varied approx. between 220 and 450 K. As a next step, we determined limited solubility data for the potassium cyanate with {formamide or N-methylformamide}. We then correlated the data by the thermodn. solubility equations with the solute activity coefficients represented by the Redlich-Kister model. Finally, we proceeded to calculate the coordinates of the invariant points, and discussed the observed phenomena.

Journal of Molecular Liquids published new progress about Amides Role: PEP (Physical, Engineering or Chemical Process), PROC (Process). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Dudko, Volodymyr published the artcileOsmotic delamination: Forceless alternative for production of nanosheets now in highly polar and aprotic solvents, Name: N-Methylformamide, the main research area is osmotic delamination nanosheet polar aprotic solvent.

Repulsive osmotic delamination is thermodynamically allowed “”dissolution”” of two-dimensional (2D) materials and therefore represents an attractive alternative to liquid-phase exfoliation to obtain strictly monolayered nanosheets with an appreciable aspect ratio with quant. yield. However, osmotic delamination was so far restricted to aqueous media, severely limiting the range of accessible 2D materials. Alkali-metal intercalation compounds of MoS2 or graphite are excluded because they cannot tolerate even traces of water. We now succeeded in extending osmotic delamination to polar and aprotic organic solvents. Upon complexation of interlayer cations of synthetic hectorite clay by crown ethers, either 15-crown-5 or 18-crown-6, steric pressure is exerted, which helps in reaching the threshold separation required to trigger osmotic delamination based on translational entropy. This way, complete delamination in water-free solvents like aprotic ethylene and propylene carbonate, N-methylformamide, N-methylacetamide, and glycerol carbonate was achieved.

Langmuir published new progress about Alkali metals Role: TEM (Technical or Engineered Material Use), USES (Uses). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Name: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Srinivasulu, A. published the artcileCopper-Catalyzed N-Alkyl Formamide Activation: Tandem Oxidative Coupling Approach for the Construction of C-N and C-O Bonds to Synthesize 3-Alkyl-1,3-Benzoxazine-2,4-Dione and 4-Methylene-3-Alkyl-1,3-Benzoxazine-2-One Derivatives, Application of N-Methylformamide, the main research area is alkyl benzoxazine dione preparation; salicyaldehyde alkyl formamide activation tandem oxidative coupling copper catalyst; methylene alkyl dihydrobenzoxazineone preparation; hydroxy acetophenone alkyl formamide activation tandem oxidative coupling copper.

Synthesis of 3,4-dihydro-2H-benzo[e][1,3]oxazin-2-ones I [R = Me, Et; R1= H, 6-Me, 7-OMe, etc.; X = O, CH2] via N-alkyl formamide activation by using copper/oxidant system via tandem oxidative coupling with salicyaldehydes/hydroxy acetophenones constructing C-N/C-O bond was reported. This protocol elucidated a method for the synthesis of pharmaceutically interested 3-alkyl-1,3-benzoxazine-2,4-dione and 1,3-methylene-3-alkyl-benzoxazine-2-one derivatives without the aid of toxic chems. such as phosgene or its derivatives

Advanced Synthesis & Catalysis published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent) (o-hydroxy). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Perry, Carolina Trindade published the artcileAmides as cryoprotectants for the freezing of Brycon orbignyanus sperm, Safety of N-Methylformamide, the main research area is Brycon sperm freezing amide cryoprotectant.

The objective of this study was to evaluate the use of different amides as an alternative for the cryopreservation of sperm from the endangered species, Bryconorbignyamus, an important fish for aquaculture in Brazil. The cryoprotectants which were combined with Beltsville Thawing Solution extender, each at the concentrations of 2.5%, 5%, 7.5%, and 10%, were as follows: (1) dimethylacetamide (DMA), (2) DMF (DMF), and (3) methylformamide (MF). The cyoprotectant methylglycol (MG, 10%) was used as a control group. Therefore, 13 treatment groups were performed. In order to assess DNA fragmentation index, lipid peroxidation, cell integrity, integrity of plasma membrane, membrane fluidity, mitochondrial functionality, and reactive oxygen species, flow cytometry was used. The best results were obtained with 7.5% DMF, among all the amides tested, with sperm motility (66%) significantly higher than the other cryoprotectants evaluated (P < .05). It also exhibited high membrane integrity (84.5%) and cell integrity (98.7%), and low membrane fluidity (20.3%) (P < .05). MG (10%) exhibited only 38% motility, lower mitochondrial protection (39.8%), and higher DNA fragmentation index (0.07), despite the high membrane integrity observed (85.6%). The DMF concentration of 7.5% demonstrated greater protection of sperm function and cellular structure, and is therefore recommended for the cryopreservation of B. orbignyamus spermatozoa. Aquaculture published new progress about Amides Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Safety of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ding, Wenwu published the artcileCharacterization of volatile compounds between industrial closed fermentation and traditional open fermentation doubanjiang-meju, Application of N-Methylformamide, the main research area is alc ester volatile compound doubanjiang meju closed open fermentation.

Doubanjiang-meju has been used as an intermediate for producing Pixian Douban (PXDB) and contributes significantly to its flavor. In this study, a profiling anal. of volatile compounds in open fermented doubanjiang-meju (OFD) and closed fermented doubanjiang-meju (CFD) was performed with gas chromatog.-mass spectrometry (GC-MS) and gas chromatog.-olfactometry (GC-O). A total of 42 and 50 volatile compounds were identified in the OFD and CFD, resp. Compared with the OFD, more diversity and higher concentrations of alcs. and esters were found in the CFD. Ten and 12 volatile compounds were finally identified as the major aroma-active compounds in the OFD and CFD, resp., by the combined anal. of aroma intensity values and odor activity values (OAVs). The CFD had significantly stronger umami and soy sauce flavor but weaker beany when compared with the OFD (p < 0.05) by quant. descriptive anal. (QDA), which were basically consistent with intensity values of aroma compounds obtained with GC-O. The results indicated that the CFD had better characteristics of volatile compounds than those of the OFD, which provided a basis of further study for the closed fermentation process of tank fermenter. European Food Research and Technology published new progress about Acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Xu, Xu-Dong published the artcileMetal-Free Regioselective Radical Cyclization of 1,6-Enynes with Carbonyl Compounds, Product Details of C2H5NO, the main research area is enyne carbonyl regioselective radical cyclization.

A regioselective cyclization of 1,6-enynes is reported by a tert-Bu hydroperoxide (TBHP)-mediated, one-pot, cascade reaction with com. available carbonyl compounds under metal- and additive-free conditions. The reaction scope includes both 1,6-enynes and carbonyl compounds A possible cascade reaction mechanism, consisting of acyl radical addition, intramol. cyclization, and hydrogen abstraction, is proposed.

ACS Sustainable Chemistry & Engineering published new progress about Alkenynes Role: RCT (Reactant), RACT (Reactant or Reagent) (1,6-Enynes). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Product Details of C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Asakawa, Tomohiro published the artcilePractical Synthesis of Polymethylated Flavones: Nobiletin and Its Desmethyl Derivatives, Name: N-Methylformamide, the main research area is nobiletin synthesis; flavone polymethoxylated preparation.

We present a practical synthesis of the polymethoxylated citrus flavone nobiletin that is suitable for use on a hundred gram scale. Ready availability of this compound and its derivatives will aid detailed chem.-biol. investigations of their biol. activities, including activation of signaling via the cAMP-dependent protein kinase A/extracellular signal-related protein kinase/cAMP response element-binding protein pathway.

Organic Process Research & Development published new progress about Methoxyflavones Role: SPN (Synthetic Preparation), PREP (Preparation). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Name: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ligterink, Niels F. W. published the artcileThe family of amide molecules toward NGC 6334I, Synthetic Route of 123-39-7, the main research area is amide mol chem network star interstellar dust.

Amide mols. produced in space could play a key role in the formation of biomols. on a young planetary object. However, the formation and chem. network of amide mols. in space is not well understood. In this work, Atacama Large Millimeter/submillimeter Array observations are used to study a number of amide(-like) mols. toward the high-mass star-forming region NGC 6334I. The first detections of cyanamide (NH2CN), acetamide (CH3C(O)NH2), and N-methylformamide (CH3NHCHO) are presented for this source. These are combined with analyses of isocyanic acid (HNCO) and formamide (NH2CHO), and a tentative detection of urea (carbamide; NH2C(O)NH2). Abundance correlations show that most amides are likely formed in related reactions occurring in ices on interstellar dust grains in NGC 6334I. However, in an expanded sample of sources, large abundance variations are seen for NH2CN that seem to depend on the source type, which suggests that the phys. conditions within the source heavily influence the production of this species. The rich amide inventory of NGC 6334I strengthens the case that interstellar mols. can contribute to the emergence of biomols. on planets.

Astrophysical Journal published new progress about Amides Role: TEM (Technical or Engineered Material Use), USES (Uses). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Synthetic Route of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wang, Wenran published the artcileProton Initiated Ligand Exchange Reactions for Colloidal Nanocrystals Functionalized by Inorganic Ligands with Extremely Weak Coordination Ability, Category: amides-buliding-blocks, the main research area is inorganic ligand nanocrystal.

Replacing initial long chain organic ligands by small, stable, and conductive inorganic ligands (ILs) via inorganic ligand exchange reaction (ILER) opens up new opportunities for the functionalization and application of colloidal nanocrystals (NCs). Although IL functionalized NCs have been successfully obtained via ILER for most ILs, some common anions, including F-, NO3-, SO42-, and ClO4- with extremely weak coordination ability, are hardly explored. Herein, we demonstrate for the first time the access of these IL capped NCs via ILER by using H+ as the electrophile reagent, which efficiently and irreversibly strips off the original organic ligands first. A long-term colloidal stability can be realized for these anion capped NCs via the replacement of H+ by other suitable monovalent counterions. It is believed that the successful capping with these hard ILs for soft NCs such as CdSe will not only promote the development of IL exchange theory and mechanism but also significantly enrich the toolbox of colloidal NCs and provide great opportunities in the design and construction of new NC-based devices.

Chemistry of Materials published new progress about IR spectra. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Category: amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Woelders, H. published the artcileFreezing chicken semen: Influence of base medium osmolality, cryoprotectants, cryoprotectant concentration, and cooling rate on post-thaw sperm survival, Computed Properties of 123-39-7, the main research area is freezing chicken sperm survival osmolality cryoprotectant cooling post thawing; CPA; CPA concentration; Chicken semen; Cooling rate; Cryopreservation; Dimethylacetamide; Extender; Freezing medium.

A classical chicken semen diluent (Lake′s 7.1 diluent) was modified to have lowered osmolalities (ranging from 290 to 410 mOsm/kg). The modified medium with physiol. osmolality of 325 mOsm/kg allowed cold storage of fresh semen for several days with very little loss of membrane integrity and motility, while high osmolalities inhibited motility. This modified medium was then used as base for freezing medium to test effects of the type and concentration of cryoprotective agent (CPA), and the cooling rate (CR). A number of CPAs (methylformamide, methylacetamide, DMF (DMF), dimethylacetamide (DMA), diethylformamide, and propylene glycol) were first compared by freezing semen with 0.6 mol/l of the resp. CPA at a cooling rate of 250 °C/min. Post-thaw motility and membrane integrity were highest with DMA and DMF. Finally, in more detailed factorial experiments, semen from individual cocks or pooled semen was frozen using CRs of 4, 50, 250, and 440 °C/min and DMA concentrations ([DMA]) of 0.4, 0.6, 1.0, and 1.5 mol/l. Straws from each semen sample x treatment combination were divided for semen assessment at three different research groups for sperm motility, membrane integrity, kinked tails, and DNA fragmentation, using microscopy, computer assisted motility anal., and flow cytometry. There were clear effects of both CR and [DMA] and their interaction. CRs 50 and 250 °C/min gave best post-thaw sperm performance. Higher DMA concentrations gave better post-thaw membrane integrity, but concentrations above 1.0 mol/l can decrease sperm velocity or even inhibit sperm motility. Therefore [DMA] may best be 0.6-1.0 mol/l at a CR of 50-250 °C/min.

Cryobiology published new progress about Cell survival. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Computed Properties of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics