Reference of 108966-71-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 108966-71-8, name is 3,4-Difluorobenzenesulfonamide belongs to amides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
In a 500 mL round-bottomed flask fitted with a condenser and N2 inlet septum was placed a stir bar, 3, 4-difluoro-benzenesulfonamide (10 g, 52 mmol), anhydrous hydrazine (10. 56 mL, 336 mmol), and acetonitrile (180 mL). The mixture was refluxed for 6 h under N2. The solvent was then removed under vacuum and the residue was treated with H2O. The separated solid was filtered and washed with H20 to give the desired product. Exact mass calculated for C6H8FN302S 205. 03, found 206. 1 (MH+).
The synthetic route of 3,4-Difluorobenzenesulfonamide has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ARENA PHARMACEUTICALS, INC.; WO2005/7658; (2005); A2;,
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