Category: 102-07-8

On October 12, 2022, Zhong, Pinyong; Wu, Junran; Liu, Jin-Biao; Luo, Nianhua published an article.Recommanded Product: 1,3-Diphenylurea The title of the article was Atmosphere-controlled selective synthesis of ureas and thioureas from isothiocyanates. And the article contained the following:

An atmosphere-controlled selective synthesis of ureas and thioureas from isothiocyanates in the presence of 4-dimethylaminopyridine is described. A series of disubstituted ureas and thioureas were prepared in air and nitrogen atm., resp. This protocol employs benign reagents and exhibits good chemoselectivity and practicality. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Recommanded Product: 1,3-Diphenylurea

The Article related to urea thiourea preparation chemoselective atm controlled, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Recommanded Product: 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yang, Jinchen; Chen, Ling; Dong, Yibo; Zhang, Jinli; Wu, Yangjie published an article in 2022, the title of the article was Di-tert-butyl peroxide (DTBP)-mediated synthesis of symmetrical N,N’-disubstituted urea/thiourea motifs from isothiocyanates in water.Application In Synthesis of 1,3-Diphenylurea And the article contains the following content:

A direct approach to N,N’-disubstituted urea/thiourea from the self-condensation reactions of isothiocyanates in water has been developed. This access tolerated a wide range of functional groups on the aromatic ring, providing a practical and environment-friendly process to N,N’-disubstituted urea/thiourea in moderate to excellent yields from safe and easily available starting materials. A plausible mechanism of the desulfurization self-condensation reaction for urea was also proposed and the role of di-tert-Bu peroxide (DTBP) and copper catalyst in the present strategy was demonstrated with the help of ESI mass spectrometry of intermediate studies. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application In Synthesis of 1,3-Diphenylurea

The Article related to urea thiourea preparation green chem, isothiocyanate desulfurization self condensation ditert butyl peroxide, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Application In Synthesis of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 31, 2021, Harish, N.; Kathyayini, N.; Baby, Bindhu; Nagaraju, N. published an article.Application of 102-07-8 The title of the article was Investigation of active sites using solid state 27Al and 31P MAS NMR in ceramic amorphous aluminophosphate materials prepared from different potassium salts of phosphate for the synthesis of diphenyl urea derivatives. And the article contained the following:

Ceramic amorphous aluminophosphate (CAmAlP) catalysts were prepared by precipitation method using different phosphate salts of potassium such as KH2PO4, K4P2O7 and K2HPO4 as well as H3PO4. The prepared materials were characterized by PXRD, FT-IR, XPS, SEM, BET Surface area, NH3-TPD, 27Al NMR and 31P NMR anal. methods. The catalytic activity of the materials was checked in the synthesis of di-Ph urea (DPU) from aniline and di-Et carbonate, under refluxing conditions. Further, the general application of the catalysts was tested using various substituted anilines. The recyclability of the catalysts was also studied. Uncertainties in percentage yields were calculated to check the reproducible surface properties. The P-XRD, BET Surface area and NH3-TPD results indicated that the materials were amorphous with mesoporous texture, surface areas and acidities in the range 200-260 m2/g and 0.4-0.7 mmol/g resp. 27Al NMR studies revealed that Al was present in three different coordination states such as tetrahedral, pentagonal and octahedral. The relative percentages of these Al sites depended on the type of the potassium precursor phosphate salt used. Both tetrahedral and pentagonal Al sites in conjunction with each other represented catalytically active sites. An increase in the pentagonal sites contributed to addnl. increments to the catalytic activity of CAmAlP. The catalyst prepared from KH2PO4 was found to be the best and demonstrated 96% DPU yield. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application of 102-07-8

The Article related to diphenyl urea preparation, aniline diethyl carbonate condensation ceramic amorphous aluminophosphate catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Application of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 26, 2022, Joseph, Devaneyan; Lee, Sunwoo published an article.Application In Synthesis of 1,3-Diphenylurea The title of the article was Reaction of Amide and Sodium Azide for the Synthesis of Acyl Azide, Urea, and Iminophosphorane. And the article contained the following:

Amides reacted with NaN3 to give the acyl azides in DMF at 25°C and produce the sym. ureas in THF/H2O at 80°C via the sequential reaction of acyl substitution and Curtius rearrangement. All acyl azides were also obtained from the secondary amides via sequential reaction of p-toluenesulfonyl chloride and NaN3. In addition, keto-stabilized iminophosphoranes were prepared from a one-pot reaction of amides, NaN3, and phosphines. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application In Synthesis of 1,3-Diphenylurea

The Article related to acyl azide sym aromatic urea iminophosphorane preparation, amide sodium azide phosphine substitution curtius rearrangement, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Application In Synthesis of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Song, Xizhong; Liu, Xiaoyu; Yu, Wei; Jin, Yi published an article in 2021, the title of the article was Amide-Assisted Rearrangement of Hydroxyarylformimidoyl Chloride to Diarylurea.HPLC of Formula: 102-07-8 And the article contains the following content:

A novel amide-assisted rearrangement reaction of hydroxybenzimidoyl chloride was established for the efficient synthesis of 1,3-diphenylurea derivatives A variety of electronically and sterically different 1,3-diphenylurea derivatives could be obtained in good to excellent yields, and a proposed reaction mechanism was also presented. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).HPLC of Formula: 102-07-8

The Article related to hydroxyarylformimidoyl chloride rearrangement, diphenylurea preparation, diarylurea, benzamide, hydroxyarylformimidoyl chloride, rearrangement, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.HPLC of Formula: 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 29, 2020, Zhang, Guofu; Cui, Yin; Zhao, Yiyong; Cui, Yunqiang; Bao, Shenxiao; Ding, Chengrong published an article.Category: amides-buliding-blocks The title of the article was A Practical Approach to Ureas and Thiocarbamates: SO2F2-Promoted Lossen Rearrangement of Hydroxamic Acid. And the article contained the following:

A simple, mild and practical method for the synthesis of sym. urea ArNHC(O)NHAr (Ar = C6H5, 1-naphthyl, 2-pyridyl, etc.) via Lossen rearrangement promoted by SO2F2, which achieves the conversion from hydroxamic acid ArC(O)NHOH to sym. urea in high selectivity and provides a new method for facile initiation of Lossen rearrangement has been described. Meanwhile, the reaction within amines R1NHR2 (R1 = 4-CH3OC6H4, 4-ClC6H4, C6H5CH2; R2 = H, Me) or thiols like 4-methylbenzene-1-thiol and phenylmethanethiol also provide the efficient synthetic strategy towards unsym. ureas C6H5NHC(O)NR1R2 or thiocarbamates like S-(p-tolyl) phenylcarbamothioate and S-benzyl phenylcarbamothioate. Significant for gram-scale application, the desired product on gram-scale by filtration without further purifn was afforded. A plausible mechanism which is supported by control exptl. and spectral data is proposed. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Category: amides-buliding-blocks

The Article related to urea preparation, hydroxamic acid lossen rearrangement, amine hydroxamic acid lossen rearrangement, thiocarbamate preparation, thiol hydroxamic acid lossen rearrangement, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 8, 2020, Yang, Wenbo; Sukhanov, Andrei A.; Lim, Jong Hyeon; Li, Xiaoxin; Meng, Yinshan; Zhao, Jianzhang; Sun, Haoling; Lee, Jin Yong; Gurzadyan, Gagik G.; Voronkova, Violeta K. published an article.Recommanded Product: 102-07-8 The title of the article was N^N Pt(II) Bisacetylide Complexes with Oxoverdazyl Radical Ligands: Preparation, Photophysical Properties, and Magnetic Exchange Interaction between the Two Radical Ligands. And the article contained the following:

To study the effect of a stable radical on the photophys. properties of a phosphorescent Pt(II) coordination framework and the intramol. magnetic interaction between radical ligands in the N^N Pt(II) bisacetylide complexes, authors prepared a series of N^N Pt(II) bis(acetylide) complexes with oxoverdazyl radical acetylide ligands. The linker between the Pt(II) center and the spin carrier was systematically varied, to probe the effect on the sign and magnitude of the spin exchange interactions between the radical ligands and photophys. properties. The complexes were studied with steady-state and femtosecond/ns transient absorption spectroscopy, continuous-wave ESR spectroscopy, and d. functional theory (DFT) computations. The transient absorption spectral studies show that the doublet excited state of the radicals are short-lived (τD ≈ 2 ps) and nonfluorescent. Moreover, the intrinsic long-lived triplet excited state (τT = 1.2μs) of the Pt(II) coordination center was efficiently quenched by the radical (τT = 6.9 ps for one representative radical Pt(II) complex). The intramol. magnetic interaction between the radical ligands through the diamagnetic Pt(II) atom was studied with temperature-dependent EPR spectroscopy; antiferromagnetic exchange interaction (-J S1S2, J = -5.4 ± 0.1 cm-1) for the complex with the shortest radical-radical distance through bridge fragments was observed DFT computations give similar results for the sign and magnitude of the J values. For complexes with larger inter-radical distance, however, very weak coupling between the radical ligands was observed (|J| < 0.7 cm-1). The results are useful for the study of the effect of a radical on the photophys. properties of the phosphorescent transition-metal complexes. A series of Pt(II) complexes containing oxoverdazyl radical ligands was prepared The length of the linker between Pt(II) center and spin carrier exerts significant effect on photophys. and magnetic property. The intrinsic long-lived triplet excited state of the Pt(II) coordination center was efficiently quenched by the presence of the radical. Antiferromagnetic interaction between the two radical ligands was observed The sign and the magnitude of the electronic spin-spin exchange was reproduced with DFT computations. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Recommanded Product: 102-07-8

The Article related to oxoverdazyl radical platinum bisacetylide preparation mol structure calculation electrochem, photophys magnetic exchange oxoverdazyl radical platinum bisacetylide complex and other aspects.Recommanded Product: 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 29, 2021, Xiao, Shouchun; Lv, Shengchen; Cheng, Zheng; Hu, Caiwei; Li, Pengxi; Nan, Fang; Liu, Xueke; Liu, Donghui; Zhou, Zhiqiang; Wang, Peng published an article.COA of Formula: C13H12N2O The title of the article was A Simple Method for the Determination of Pharmaceutical and Personal Care Products in Fish Tissue Based on Matrix Solid-Phase Dispersion. And the article contained the following:

A simple and effective pretreatment method based on matrix solid-phase dispersion was developed for the determination of pharmaceutical and personal care products (PPCPs) and their metabolites in fish by high-performance liquid chromatog. tandem mass spectrometry. The type and amount of dispersant, adsorbent, and eluting solvent were optimized by a single-factor experiment and Box-Behnken design. Under the optimal conditions with 2.5 g of Florisil as a dispersant, 500 mg of C18 as an adsorbent, and 5 mL of acetonitrile as an eluting solvent, the recoveries ranged from 70.4 to 99.9% with relative standard deviations less than 10.5%, and the limits of quantitation ranged from 0.13 to 1.01μg/kg. The developed method was successfully applied to detect PPCPs in marketed fish, and five PPCPs, including triclocarban, sulfadiazine, sulfadimidine, sulfamethoxazole, and carbamazepine, were detected at trace levels. The proposed method, which has the advantages of short anal. time, less solvent consumption, and high sensitivity, can be used for the determination of trace PPCPs in fish. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).COA of Formula: C13H12N2O

The Article related to fish contamination pharmaceutical personal care product matrix solid dispersion, box−behnken design, fish, matrix solid-phase dispersion, pharmaceutical and personal care products and other aspects.COA of Formula: C13H12N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 31, 2021, Yadav, Mangal S.; Singh, Sumt K.; Agrahari, Anand K.; Singh, Anoop S.; Tiwari, Vinod K. published an article.Reference of 1,3-Diphenylurea The title of the article was N -Acylbenzotriazoles as Proficient Substrates for an Easy Access to Ureas, Acylureas, Carbamates, and Thiocarbamates via Curtius Rearrangement Using Diphenylphosphoryl Azide (DPPA) as Azide Donor. And the article contained the following:

A diverse range of ureas RNHC(O)NHC(O)R1 [R = Ph, 2-IC6H4, 3-BrC6H4, etc.; R1 = Ph, 2-IC6H4], N-acylureas R1NHC(O)NHR2 [R1 = Ph, 3-BrC6H4, 2-MeOC6H4, etc; R2 = Ph, 2-BrC6H4, 2-IC6H4], carbamates and thiocarbamates R1NHC(O)R2 [R1 = Ph, 3,5-di-MeC6H3, 3-MeC6H4; R2 = OPh, SPh, S(2-MeC6H4), etc.] was synthesized in good to excellent yields by reacting N-acylbenzotriazoles individually with amines/amides/phenols/thiols in the presence of diphenylphosphoryl azide (DPPA) as a suitable azide donor in anhydrous toluene at 110°C for 3-4 h. In this route, DPPA was found to be a good alternative to trimethylsilyl azide and sodium azide for the azide donor in Curtius degradation The high reaction yields, one-pot and metal-free conditions, straightforward nature, easy handling, use of readily available reagents and in many cases avoidance of column chromatog. were the notable features of the devised protocol. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Reference of 1,3-Diphenylurea

The Article related to urea or acylurea preparation, acylbenzotriazole amine or amide curtius rearrangement dppa, carbamate or thiocarbamate preparation, phenol or thiol acylbenzotriazole curtius rearrangement dppa and other aspects.Reference of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 29, 2020, Serrano, Joao L.; Soeiro, Pedro F.; Reis, Melani A.; Boto, Renato E. F.; Silvestre, Samuel; Almeida, Paulo published an article.Electric Literature of 102-07-8 The title of the article was Synthesis and process optimization of symmetric and unsymmetric barbiturates C5-coupled with 2,1-benzisoxazoles. And the article contained the following:

An unexpected formation of sym. 3-substituted 2,1-benzisoxazoles I [X = O, S; R = R1 = H, Ph, Me] through reduction of 5-(2-nitrobenzylidene)barbiturates II has been described. This reductive intramol. heterocyclization probably involves a nitroso intermediary. To improve the previous reaction conditions, the nature of the reducing agent and additives, reaction time and solvents were evaluated. By applying the optimized conditions, several sym. I [X = O, S; R = R1 = H, Ph, Me] and unsym. barbiturates C5-coupled with 2,1-benzisoxazoles I [X = S; R = Ph; R1 = H, 3-chlorophenyl, 4-chlorophenyl, 4-fluorophenyl, 4-iodophenyl] were prepared with an yield of 52-87%. From this set, seven compounds I (X = S, R = R1 = Me; X = O, R = R1 = Ph; X = S, R = Ph, R1 = H, 3-chlorophenyl, 4-chlorophenyl, 4-fluorophenyl, 4-iodophenyl) were novel and the unsym. nature of the (thio)barbituric acid moiety was explored. For that, the total synthesis, starting from the resp. urea or thiourea, was successfully performed, and 11 thiobarbiturates, benzylidene barbiturate and thiobarbiturate precursors are described. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Electric Literature of 102-07-8

The Article related to benzisoxazole preparation, nitrobenzylidene barbiturate reductive heterocyclization, 2,1-benzisoxazoles, anthranils, barbituric acid derivatives, nitroaromatic reduction, process optimization and other aspects.Electric Literature of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics