Category: 102-07-8

On September 22, 2020, Harrier, Danielle D.; Kenis, Paul J. A.; Guironnet, Damien published an article.Computed Properties of 102-07-8 The title of the article was Ring-Opening Polymerization of Cyclic Esters in an Aqueous Dispersion. And the article contained the following:

Aqueous polymer dispersions are commodity materials produced on a multimillion-ton scale annually. Today none of these materials are biodegradable because the process by which they are made is not compatible with the synthesis of biodegradable polymers. Herein, we report a droplet microfluidic encapsulation strategy for protecting a water incompatible ring-opening polymerization (ROP) catalyst from the aqueous phase, yielding biodegradable polymer particles dispersed in water. Polymerization yields 300μm sized particles comprised of biodegradable poly(δ-valerolactone) with mol. weights up to 19.5 kg mol-1. The success of this approach relies on simultaneous precise control of the kinetics of polymerization, the rate of mass transfer, and fluid mechanics. The power of this methodol. was demonstrated by the synthesis of cross-linked polymer particles through the copolymerization of bis(ε-caprolactone-4-yl)propane and δ-valerolactone, producing cross-linked polymer particles with mol. weights reaching 65.3 kg mol-1. Overall, this encapsulation technique opens the door for the synthesis of biodegradable polymer latex and processable, biodegradable elastomers. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Computed Properties of 102-07-8

The Article related to ring opening polymerization cyclic ester aqueous dispersion microfluidic encapsulation, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Computed Properties of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Waleed, Hadeer Q.; Csecsi, Marcell; Konyhas, Vivien; Boros, Zsanett R.; Viskolcz, Bela; Fejes, Zsolt; Fiser, Bela published an article in 2022, the title of the article was Aliphatic tertiary amine catalyzed urethane formation – a combined experimental and theoretical study.Application In Synthesis of 1,3-Diphenylurea And the article contains the following content:

A kinetic and mechanistic investigation of the alcoholysis of Ph isocyanate (PhNCO) using stoichiometric butan-1-ol (BuOH) in acetonitrile in the presence of different tertiary amine catalysts was performed. The reaction mechanisms in the absence and presence of exptl. applied catalysts were described by using the G3MP2BHandHLYP composite method. The apparent activation energies obtained from the calculations were in good agreement with the exptl. data (ΔΔE = <2 kJ mol-1). Both exptl. and theor. results proved the important effect of tertiary amine catalysts on urethane formation. These results can aid in polyurethane catalyst design and development. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application In Synthesis of 1,3-Diphenylurea

The Article related to phenylisocyanate butanol tertiary amine alcoholysis kinetics mechanism, Physical Organic Chemistry: Addition, Elimination, and Substitution Reactions and other aspects.Application In Synthesis of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 17, 2021, Arisawa, Mieko; Mizuno, Taro; Nozawa-Kumada, Kanako; Itto-Nakama, Kaori; Furuta, Miyu; Tanii, Saori published an article.Application of 102-07-8 The title of the article was Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl)ureas Involving an Equilibrium Shift. And the article contained the following:

Unsym. di(heteroaryl)ureas such as Ar1NHC(O)NHAr2 [Ar1 = pyrimidin-2-yl, 4-methoxyphenyl, 4,6-dimethylpyrimidin-2-yl, etc.; Ar2 = Ph, 4-pyridyl, 4-methoxy-2-pyridyl, etc.] were efficiently synthesized from two sym. ureas, Ar1NHC(O)NHAr1 and Ar2NHC(O)NHAr2, by rhodium-catalyzed exchange reactions. The equilibrium in some of the reactions could be shifted to the formation of unsym. ureas by the aggregation of the dimers formed by inter- and intramol. hydrogen bonding. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application of 102-07-8

The Article related to di heteroaryl urea preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Application of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 1, 2020, Pacheco, Kelvin A.; Bresciani, Antonio E.; Nascimento, Claudio A. O.; Alves, Rita M. B. published an article.COA of Formula: C13H12N2O The title of the article was Assessment of property estimation methods for the thermodynamics of carbon dioxide-based products. And the article contained the following:

Carbon dioxide can be used as feedstock to produce chems. It represents a stimulating defiance to manufacture novel cost competitive materials with less environmental impact, besides to investigate new opportunities for catalysts and industrial chem. The contribution of carbon dioxide conversion goes beyond lowering global warming, by reducing fossil resource depletion or even yielding more benign production pathways. Albeit promising, the literature data regarding the quantity of energy needed to convert carbon dioxide into chems. is limited and narrowed to the most studied processes and products. In order to understand and model the formation of species using carbon dioxide as raw material, some basic thermodn. data are needed. The development of detailed reaction schemes in the field is also scarce. To enhance and further complete the database of the products obtained from carbon dioxide, this study investigates different procedures to estimate the basic thermodn. properties of the reactants and products of these reactions. To date various methods have been developed and introduced to determine the gas-phase standard enthalpies of formation and Gibbs energy. Among them, group additivity and semi-empirical methods are widely employed due to their accuracy and effort time for implementation compared to more rigorous methods. Semi empirical quantum-chem. methods were compared with group additivity methods. Available literature data were used to select the best method for property estimation of the whole set of species, whereby produced from carbon dioxide. The products from carbon dioxide were categorized in sixteen chem. classes, the reaction enthalpy for the direct route to manufacture the products were assessed and indicate a large difference among the classes. The results of this investigation show that semi empirical quantum-chem. methods revealed to be more accurate for the studied species; addnl., the method demonstrates robustness in estimating the properties. Together, these results provide important insights into the thermodn. of carbon dioxide related products. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).COA of Formula: C13H12N2O

The Article related to carbon dioxide product thermodn property, Thermodynamics, Thermochemistry, and Thermal Properties: Thermochemical Properties and other aspects.COA of Formula: C13H12N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 19, 2020, Soccio, Michelina; Mazzoni, Rita; Lucarelli, Carlo; Quattrosoldi, Silvia; Cingolani, Andrea; Fiorini, Maurizio; Lotti, Nadia; Tabanelli, Tommaso published an article.Recommanded Product: 1,3-Diphenylurea The title of the article was Urea and Polyurea Production: An Innovative Solvent- and Catalyst-Free Approach through Catechol Carbonate. And the article contained the following:

The peculiar reactivity of catechol carbonate (CC) with amines and polyamines in both solvent- and catalyst-free conditions is herein described. In all the tests performed at room temperature, CC conversion reached 100% in a few seconds leading to the selective formation of the corresponding 2-hydroxyphenylcarbamate. This compound is further rapidly converted to the disubstituted urea by the consecutive nucleophilic attack of another amine. Noteworthy, the application of this approach can be successfully extended to the one-pot bioamine-based synthesis of polyurea as herein proposed for the first time in the literature. The reaction is of general purpose for primary amines, and catechol can be easily recovered by sublimation as pure crystals ready to be recycled for the synthesis of new CC. An exception is related to the reactivity of secondary amine, which leads to the selective formation of substituted phenolic carbamates (e.g., 2-hydroxyphenyl diethylcarbamate), suitable as intermediates in medicinal chem. Superior reactivity is displayed by catechol carbonate toward aminolysis yielding urea and polyurea in mild, solvent- and catalyst-free conditions. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Recommanded Product: 1,3-Diphenylurea

The Article related to urea production solvent catalyst free catechol carbonate amine, polyurea catechol carbonate diamine polym green chem, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.Recommanded Product: 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Marshall, Sarah R.; Singh, Anmol; Wagner, Jacqueline N.; Busschaert, Nathalie published an article in 2020, the title of the article was Enhancing the selectivity of optical sensors using synthetic transmembrane ion transporters.Synthetic Route of 102-07-8 And the article contains the following content:

Herein, we introduce a new method to optimize the properties of optical sensors, coined the transporter-liposome-fluorophore (TLF) approach. It is shown that this approach can greatly improve the selectivity of the sensor, increase the dynamic range and maintain the sensitivity of the original fluorophore. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Synthetic Route of 102-07-8

The Article related to enhancing selectivity optical sensor synthetic transmembrane ion transporter, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Luminescence and other aspects.Synthetic Route of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zhang, Qiao; Yuan, Hao-Yu; Lin, Xiao-Tao; Fukaya, Norihisa; Fujitani, Tadahiro; Sato, Kazuhiko; Choi, Jun-Chul published an article in 2020, the title of the article was Calcium carbide as a dehydrating agent for the synthesis of carbamates, glycerol carbonate, and cyclic carbonates from carbon dioxide.Synthetic Route of 102-07-8 And the article contains the following content:

Carbon dioxide (CO2) is a nontoxic and inexpensive C1 building block, which can be used for the synthesis of valuable chems. such as aromatic carbamates from anilines and methanol (MeOH), glycerol carbonate from glycerol, and cyclic carbonates from diols. However, these reactions generate water as the byproduct and suffer from thermodn. limits, which lead to low yields. Calcium carbide (CaC2) is a renewable chem., which can be recycled from calcium that is abundant in the Earth’s crust. Furthermore, CaC2 rapidly reacts with water. The authors used CaC2 as a dehydrating agent for the direct synthesis of carbamates (including polyurethane precursors) from amines, CO2, and MeOH. All reagents were com. available. In addition, CaC2 was employed for the synthesis of glycerol carbonate from glycerol and CO2 with a zinc catalyst and N-donor ligand. A similar protocol was applied to synthesize cyclic carbonates from diols and CO2. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Synthetic Route of 102-07-8

The Article related to carbonate glycerol carbonate carbamate preparation calcium carbide carbon dioxide, Heterocyclic Compounds (More Than One Hetero Atom): Dioxoles, Oxathioles, Dithioles and other aspects.Synthetic Route of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 15, 2022, Muranaka, Ryo; Liu, Yue; Okada, Itsuumi; Okazoe, Takashi; Tsuda, Akihiko published an article.Quality Control of 1,3-Diphenylurea The title of the article was Photo-on-Demand Phosgenation Reactions with Chloroform for Selective Syntheses of N-Substituted Ureas and Isocyanates. And the article contained the following:

Two new reaction processes involving the in situ oxidative photochem. conversion of CHCl3 to COCl2 allowed selective syntheses of N-substituted ureas and isocyanates from amines. (I) A CHCl3 solution containing an amine and an organic base under O2 bubbling provided the urea derivative under exposure to UV light generated from a low-pressure mercury lamp at 20-40°C. (II) A two-step reaction involving the oxidative photodecomposition of CHCl3 at lower temperatures and subsequent sequential injections of an amine and organic base into the sample solution provided the isocyanate in high yield. The reaction processes of (I) and (II) capitalize on the solution conditions of [COCl2] < [amine] and [COCl2] > [amine], resp., to result in 1:2 and 1:1 reactions. In general, isocyanates, especially aromatic and haloalkyl ones, readily undergo hydrolysis in the presence of an organic base. However, with the advantage of synthesizing the isocyanates in CHCl3 solvent, direct addition of monoalcs. and diols to the as-prepared sample solution containing the diisocyanate allowed the one-pot syntheses of biscarbamates and polyurethanes, resp. The reactions developed in this study are simple, safe, and inexpensive methods of synthesizing N-substituted ureas and isocyanates, and derivatives of isocyanates such as carbamates and polyurethanes. The present new methods can replace current synthetic methods using COCl2 in both academia and industry. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Quality Control of 1,3-Diphenylurea

The Article related to substituted urea isocyanate preparation, chloroform amine phosgenation oxidative photochem, Aliphatic Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Quality Control of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ma, Haowen; Feng, Jiajie; Zhou, Wei; Chen, Chen; Deng, Zhuoji; Zhou, Fengtao; Ouyang, Yifan; Zhang, Xinhao; Cai, Qian published an article in 2021, the title of the article was Copper(I)-catalyzed asymmetric intramolecular C-arylation with ureas as the additives: highly enantioselective formation of spirooxindoles.Application of 102-07-8 And the article contains the following content:

An enantioselective synthesis of spirooxindoles I [Y = CH2, O, NMe; R = Me, allyl, Bn, etc.; R1 = H, 5-F, 6-Me, etc.] via copper-catalyzed asym. intramol. C-arylation reaction with ureas as the co-catalysts was developed. By formation of hydrogen bonds with 1,3-dicarbonyl structures, ureas could activate the substrates, stabilize the carbanion intermediates and the products, and fix the syn-configurations of 1,3-dicarbonyl structures. They help enhance the reactivity, prevent side reactions and improve the enantioselectivities. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application of 102-07-8

The Article related to spirooxindole enantioselective preparation, cyclic beta ketoamide preparation copper catalyst ullmann hurtley arylation, Heterocyclic Compounds (One Hetero Atom): Spiro Compounds With One Hetero Atom In Each Ring and other aspects.Application of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Shaifali; Sheetal; Bains, Rohit; Kumar, Ajay; Ram, Shankar; Das, Pralay published an article in 2020, the title of the article was Supported palladium catalyzed aminocarbonylation of aryl iodides employing bench-stable CO and NH3 surrogates.Synthetic Route of 102-07-8 And the article contains the following content:

A simple, efficient and phosphine free protocol for carbonylative synthesis of primary aromatic amides under polystyrene supported palladium (Pd@PS) nanoparticle (NP) catalyzed conditions has been demonstrated. Herein, instead of using two toxic and difficult to handle gases simultaneously, we have employed the solid, economical, bench stable oxalic acid as the CO source and ammonium carbamate as the NH3 source in a single pot reaction. For the first time, we have applied two non-gaseous surrogates simultaneously under heterogeneous catalyst (Pd@PS) conditions for the synthesis of primary amides using an easy to handle double-vial (DV) system. The developed strategy showed a good functional group tolerance towards a wide range of aryl iodides and afforded primary aromatic amides in good yields. The Pd@PS catalyst was easy to sep. and can be recycled up to four consecutive runs with small loss in catalytic activity. We have successfully extended the scope of the methodol. to the synthesis of isoindole-1,3-diones from 1,2-dihalobenzene, 2-halobenzoates and 2-halobenzoic acid following double and single carbonylative cyclization approaches. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Synthetic Route of 102-07-8

The Article related to aryl iodide aminocarbonylation palladium polystyrene, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Synthetic Route of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics