Category: 102-07-8

On December 31, 2021, Vala, Anand; Parmar, Nirali; Soni, Jigar Y.; Kotturi, Sharadsrikar; Guduru, Ramakrishna published an article.HPLC of Formula: 102-07-8 The title of the article was 1,4,2-Dioxazol-5-ones as Isocyanate Equivalents: An Efficient Synthesis of 2-Quinolinones via β-Keto Amides. And the article contained the following:

Under thermal conditions, 1,4,2-dioxazol-5-ones were known to undergo decarboxylation followed by Lossen’s rearrangement to yield isocyanates. A safe and efficient method for the generation and capture of isocyanates to gave β-keto amides I [R1 = H, 3-Cl, 4-OMe; R2 = H, 4-Br, 4-F, etc.] was established. The β-keto amides I were efficiently converted into quinolin-2-ones II [R1 = H, 3-Cl, 4-OMe; R2 = H, 4-Br, 4-F, etc.] in good to excellent yields. Importantly, the method was transition metal-free and involved a simple two-step procedure that could be of interest to the pharmaceutical industry. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).HPLC of Formula: 102-07-8

The Article related to quinolinone preparation, beta keto amide preparation polyphosphoric acid cyclization, dioxazolone acetophenone thermal degradation isocyanate in situ trapping, Heterocyclic Compounds (One Hetero Atom): Quinolines and Isoquinolines and other aspects.HPLC of Formula: 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 31, 2022, Hyder, M.; O’Donnell, A. D.; Chippindale, A. M.; German, I. M.; Harries, J. L.; Shebanova, O.; Hamley, I. W.; Hayes, W. published an article.Name: 1,3-Diphenylurea The title of the article was Tailoring viscoelastic properties of dynamic supramolecular poly(butadiene)-based elastomers. And the article contained the following:

The discovery and development of new adhesive materials is critical for real-world applications of polymeric composite materials. Herein, we report the design and synthesis of a library of structurally related phase-separated supramol. polyurethanes whose mech. properties and adhesive characteristics can be enhanced through minor structural modifications of the polymer end-group. The interplay between phase separation of the hard domain polar end-groups and soft polybutadiene domains, coupled with tuneable self-assembly afforded by the polar end-groups, gives rise to a class of materials with tuneable mech. properties. Exceptionally strong supramol. adhesives and mech. robust self-healing elastomers were identified. The mech. properties were investigated through tensile testing. Finally, rheol. anal. of the supramol. materials was used to identify suitable healing and adhesive temperatures in addition to elucidate the supramol. polyurethanes’ thermal-responsive nature. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Name: 1,3-Diphenylurea

The Article related to polybutadiene elastomer synthesis phase separation viscoelastic property, Synthetic Elastomers and Natural Rubber: Physical Properties and Testing and other aspects.Name: 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 7, 2022, Rostami, Ali; Ebrahimi, Amirhossein; Sakhaee, Nader; Golmohammadi, Farhad; Al-Harrasi, Ahmed published an article.Computed Properties of 102-07-8 The title of the article was Microwave-Assisted Electrostatically Enhanced Phenol-Catalyzed Synthesis of Oxazolidinones. And the article contained the following:

An electrostatically enhanced phenol is utilized as a straightforward, sustainable, and potent one-component organocatalyst for the atom-economic transformation of epoxides to oxazolidinones under microwave irradiation Integrating a pos. charged center into phenols over a modular one-step preparation gives rise to a bifunctional system with improved acidity and activity, competent in rapid assembly of epoxides and isocyanates under microwave irradiation in a short reaction time (20-60 min). A careful assessment of the efficacy of various pos. charged phenols and anilines and the impact of several factors, such as catalyst loading, temperature, and the kind of nucleophile, on catalytic reactivity were examined Under neat conditions, this one-component catalytic platform was exploited to prepare more than 40 examples of oxazolidinones from a variety of aryl- and alkyl-substituted epoxides and isocyanates within minutes, where up to 96% yield and high degree of selectivity were attained. DFT calculations to achieve reaction barriers for different catalytic routes were conducted to provide mechanistic understanding and corroborated the exptl. findings in which concurrent epoxide ring-opening and isocyanate incorporation were proposed. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Computed Properties of 102-07-8

The Article related to oxazolidinone preparation microwave irradiation, epoxide isocyanate cycloaddition electrostatically enhanced phenol catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Computed Properties of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yingcharoen, Prapussorn; Natongchai, Wuttichai; Poater, Albert; D’ Elia, Valerio published an article in 2020, the title of the article was Intertwined chemistry of hydroxyl hydrogen-bond donors, epoxides and isocyanates in the organocatalytic synthesis of oxazolidinones versus isocyanurates: rational catalytic investigation and mechanistic understanding.Synthetic Route of 102-07-8 And the article contains the following content:

The use of hydroxyl hydrogen bond donors (HBDs) was investigated in cycloaddition of isocyanates to epoxides to afford 3-aryl-2-oxazolidinones I [R1 = H, 2-Me, 4-NO2, etc.; R2 = Et, CH2OCH2CH=CH2, CH2OCH2Ph, etc.] as a class of heterocycles with promising applications in pharmaceutical chem. In this work, a systematic investigation of readily available HBDs as catalytic components of binary systems for latter cycloaddition reaction was carried out. Such a study showed crucial role of HBDs’ pKa1 value in driving selectivity of reaction toward oxazolidinones as opposed to formation of oligomeric isocyanurates or ureas, with most acidic HBDs (pKa1: 3-4) displaying best catalytic performance. Mechanistic investigation with the support of DFT calculations allowed deeper insight into reaction dynamics and origin of exptl. observed chemoselectivity for cyclization vs. cyclo-oligomerization at different reaction temperatures, shedding light on a strictly intertwined chem. between the HBDs, isocyanates and epoxides. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Synthetic Route of 102-07-8

The Article related to aryl oxazolidinone chemoselective preparation dft reaction mechanism, isocyanate epoxide cycloaddition organocatalyst hydrogen bond donor, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Synthetic Route of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 30, 2020, Zhang, Hui; Cui, Xiaojing; Wang, Hongliang; Wang, Yuqi; Zhao, Yuhua; Ma, Hui; Chai, Lin; Wang, Yingxiong; Hou, Xianglin; Deng, Tiansheng published an article.Reference of 1,3-Diphenylurea The title of the article was Degradation of polycarbonate-based polyurethane via selective cleavage of carbamate and urea bonds. And the article contained the following:

Deep eutectic solvents (DESs) have attracted broad attention due to their low cost and toxicity, easy preparation, good biol. compatibility and similar characteristics to those of ionic liquids In this study, a DES system composed of choline chloride and urea has been applied for the controllable degradation of polyurethane (PU). By the combination of Fourier transform IR spectroscopy (FT-IR), NMR spectroscopy (NMR) and matrix-assisted laser anal. ionization time-of-flight mass spectrometer (MALDI-TOF-MS), the selective cleavage of carbamate and urea bonds with little damage on carbonate bonds was achieved in the DES system by the regulation of reaction conditions, which favored the recovery of both valuable polycarbonate diol (PCDL) and 3,3′-Dimethyl-[1,1′-biphenyl]-4,4′-Diamine (o-toluidine). The degradation rate of PU and the yield of PCDL reached 100% and 57.4% resp. under mild conditions (1 atm, 170°C, 8 h). A possible degradation mechanism was proposed based on the exptl. results, in which the synergistic effect of choline chloride and urea activated largely the carbamate bond and thus led to a controlled degradation of PU. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Reference of 1,3-Diphenylurea

The Article related to polycarbonate urethane rubber degradation deep eutectic solvent, Synthetic Elastomers and Natural Rubber: Chemical Properties Of Elastomers and other aspects.Reference of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Madej, Dominik; Konopko, Adrian; Piotrowski, Piotr; Krogul-Sobczak, Agnieszka published an article in 2020, the title of the article was Pd nanoparticles and mixture of CO2/CO/O2 applied in the carbonylation of aniline.Related Products of 102-07-8 And the article contains the following content:

CO2 is a compound of high stability which proves useful in some organic syntheses as a solvent or component decreasing explosivity of gases. It is also a good carbonylating agent for aliphatic amines although not for aromatic ones, the latter being carbonylated with phosgene or, as in our previous works, with CO/O2 in the presence of Pd(II) complexes. In this work we have used the mixture of CO/O2 and CO2 for carbonylation of aniline to N,N’-diphenylurea. After optimization of the reaction conditions (56% of CO2 in CO2/CO mixture) we studied the activity of three kinds of pre-catalysts: (a) Pd(II) complexes, (b) Pdblack, and (c) palladium nanoparticles (PdNPs) in the presence of derivatives of pyridine (XnPy). The highest conversion of aniline (with selectivity towards N,N-diphenylurea ca. 90%) was observed for PdNPs. The results show that catalytic cycle involves Pd(0) stabilized by pyridine ligand as active species. Basing on this observation, we put the hypothesis that application of PdNPs instead of Pd(II) complex can efficiently reduce the reaction time. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Related Products of 102-07-8

The Article related to palladium nanoparticle carbon dioxide monoxide oxygen aniline carbonylation, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Catalysts and other aspects.Related Products of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 8, 2022, Liu, Jingjing; Gnanou, Yves; Feng, Xiaoshuang published an article.Quality Control of 1,3-Diphenylurea The title of the article was Expanding the Scope of Boron-Based Ate Complexes by Manipulating Their Reactivity: The Case of Cyclic Esters and Their (Co)Polymers. And the article contained the following:

The value and merit of triethylborane (TEB)-based ate complexes for the synthesis of various oxygenated polymers have been recently illustrated through successful examples of homopolymerization of epoxides and of their copolymerization with CO2, CS2, COS, anhydrides, isocyanates, etc. To further expand the scope of TEB-based initiating systems to a broader family of oxygenated polymers, they were used in this study to anionically polymerize cyclic esters and to copolymerize the latter monomers with propylene oxide (PO). To promote a fast and controlled ring-opening polymerization (ROP) of cyclic esters, hydrogen-bonding donors such as amines and (thio)ureas were added to TEB-based ate complexes used as initiators. Only under these conditions could the ROP of ε-caprolactone (CL), δ-valerolactone (VL), and L-lactide (LLA) proceed under controlled conditions with hardly detectable intra- or intermol. transesterifications. The role of amines and (thio)ureas when used alone or together in association with these boron-based initiators is discussed in detail. The controlled character of the polymerization of CL, VL, and LLA is attested by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-ToF MS) and other characterization techniques. As examples of the far-reaching potential of these borane-based ate complexes, random P(PO-co-VL) copolymers were derived by statistical copolymerization of VL with PO and various well-defined block copolymers-PPO-b-PVL, PVL-b-PPO, PPO-b-PCL, PPO-b-PLLA, and PPO-b-PVL-b-PPO-were grown by sequential polymerization of the corresponding monomers. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Quality Control of 1,3-Diphenylurea

The Article related to boron ate complex cyclic ester polymer, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Quality Control of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 22, 2020, Park, Nathaniel H.; Zubarev, Dmitry Yu.; Hedrick, James L.; Kiyek, Vivien; Corbet, Christiaan; Lottier, Simon published an article.Safety of 1,3-Diphenylurea The title of the article was A Recommender System for Inverse Design of Polycarbonates and Polyesters. And the article contained the following:

The convergence of artificial intelligence and machine learning with material science holds significant promise in rapidly accelerating the development timelines of new high-performance polymeric materials. Within this context, we report an inverse design strategy for polycarbonate and polyester discovery based on a recommendation system that proposes polymerization experiments that are likely to produce materials with targeted properties or characteristics. Following the recommendations of the system driven by the historical ring-opening polymerization results, we carried out experiments targeting specific ranges of monomer conversion and dispersity for polyesters or polycarbonates. The results of the experiments were in close agreement with the recommendation targets with few false negatives or positives obtained for each class. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Safety of 1,3-Diphenylurea

The Article related to recommender system design polycarbonate polyester, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Safety of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 6, 2020, Jurrat, Mark; Pointer-Gleadhill, Benjamin J.; Ball, Liam T.; Chapman, Andy; Adriaenssens, Louis published an article.Application In Synthesis of 1,3-Diphenylurea The title of the article was Polyurethanes and Polyallophanates via Sequence-Selective Copolymerization of Epoxides and Isocyanates. And the article contained the following:

Aryl isocyanates are introduced as comonomers for ring opening copolymerization (ROCOP) with epoxides. Informed by studies of reaction kinetics, we show that divergent sequence selectivity for AB- and ABB-type copolymers can be achieved with a single dimagnesium catalyst. The resulting materials resp. constitute a new class of polyurethane (PU) and a new class of material featuring an unprecedented backbone structure, the polyallophanate (PA). The successful use of isocyanate comonomers in this way marks a new direction for the field of ROCOP, while providing distinct opportunities for expansion of PU structural diversity. Specifically, the methodol. reported herein delivers PUs featuring fully substituted (tertiary) carbamyl nitrogen atoms, a structural motif that is almost inaccessible via extant polymerization strategies. Thus, in one step from com. available comonomers, our methodol. expands the scope of ROCOP and gives access to diverse materials featuring both privileged (PU) and unexplored (PA) microstructures. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application In Synthesis of 1,3-Diphenylurea

The Article related to polyurethane polyallophanate sequence copolymerization epoxide isocyanate, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Application In Synthesis of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 27, 2020, Lin, Binhong; Jadrich, Caleb N.; Pane, Vince E.; Arrechea, Pedro L.; Erdmann, Tim; Dausse, Charles; Hedrick, James L.; Park, Nathaniel H.; Waymouth, Robert M. published an article.Category: amides-buliding-blocks The title of the article was Ultrafast and Controlled Ring-Opening Polymerization with Sterically Hindered Strong Bases. And the article contained the following:

The controlled anionic ring-opening polymerization of lactones and siloxanes is carried out in continuous-flow reactors. Anionic ring-opening polymerization of cyclic esters with strong, soluble bases such as potassium tert-butoxide (KOtBu) is typically performed as batch reactions, leading to broad dispersity and poor control over the mol. weight (Mn) mainly because of transesterification reactions. Although reactions with strong bases give rise to “uncontrolled” polymerizations, a variety of transition metal-based and organocatalysts have been developed with the goal of reliably controlling the dispersity and Mn. Herein, we show that the rapid mixing and short residence times accessible with a continuous-flow apparatus can enable the controlled polymerization of low-reactivity monomers such as δ-valerolactone and ε-caprolactone on millisecond time scales using a base [such as KOtBu or potassium bis(trimethylsilyl)amide (KHMDS)] in conjunction with a primary alc. These reactions exhibit characteristics capable of producing narrow dispersity with predictable mol. weights and can rapidly generate well-defined block copolymers with residence times below 0.1 s. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Category: amides-buliding-blocks

The Article related to ultrafast controlled ring opening polymerization sterically hindered strong base, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics