On August 31, 2010, Ali, Muhammad Shaiq; Shahnaz; Tabassum, Sobia; Ogunwande, Isiaka Ajani; Pervez, Muhammad Kashif; Ibrahim, Oladosu Adebayo published an article.Safety of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide The title of the article was Naturally occurring antifungal aromatic esters and amides. And the article contained the following:
During the search of antifungal natural products from terrestrial plants, a new long chained aromatic ester named grandiflorate (1) along with spatazoate (2) from Portulaca grandiflora and N-[2-methoxy-2-(4-methoxyphenyl) ethyl]-trans-cinnamide (3) and aegeline (4) from Solanum erianthum of Nigeria were isolated and tested against six fungal species. The known constituents 2-4 have not been reported so far from mentioned investigated plants. Structures of the isolated compounds were elucidated with the aid of spectroscopic techniques including two dimensional NMR experiments Among the compounds 1-4, the esters (1-2) found more potent than amides (3-4) against Candida albicans and Aspergillus flavus. The new compound grandiflorate (1) gave response against all tested fungal species while aegeline (4) was found to give lowest inhibition during this study. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Safety of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide
The Article related to grandiflorate structure spatazoate fungicide portulaca, methoxymethoxyphenylethylcinnamide aegeline solanum fungicide, Plant Biochemistry: Composition and Products and other aspects.Safety of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics