On November 23, 2021, Fan, Qinghua; Zhang, Shanshan; Chen, Fei; He, Yanmei published a patent.Recommanded Product: 167316-28-1 The title of the patent was Asymmetric hydrogenation kinetic resolution of racemic polysubstituted dihydroisoquinoline. And the patent contained the following:
The invention discloses an asym. hydrogenation kinetic resolution method of racemic polysubstituted dihydroisoquinoline, which can realize the resolution of racemic polysubstituted dihydroisoquinoline compounds, and obtain a single optical isomer of polysubstituted chiral tetrahydroisoquinoline compounds and polysubstituted chiral dihydroisoquinoline compounds with certain optical purity. The asym. hydrogenation kinetic resolution method comprises the following steps: in the presence of chiral diamine metal catalyst, the mixture containing enantiomers of polysubstituted dihydroisoquinoline compounds is asym. hydrogenated with hydrogen. The experimental process involved the reaction of N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-1,1,1-trifluoromethanesulfonamide(cas: 167316-28-1).Recommanded Product: 167316-28-1
The Article related to asym hydrogenation kinetic resolution racemic polysubstituted dihydroisoquinoline, Heterocyclic Compounds (One Hetero Atom): Quinolines and Isoquinolines and other aspects.Recommanded Product: 167316-28-1
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics