On September 25, 2001, Li, Yan-yun; Yin, Zhen-yan; Hu, Ying-xi; Liu, Xia; Chen, Chi-yang; Liu, Bin published an article.SDS of cas: 97-09-6 The title of the article was Synthesis of 2-nitrophenol-4-sulfonylamide. And the article contained the following:
2-Nitrophenol-4-sulfonylamide was synthesized by sulfochlorination, ammoniation, hydrolysis from o-nitrochlorobenzene being as raw materials. The reaction conditions were optimized in material proportion, reaction temperature, reaction time. The optimum technol. conditions were obtained as the follows: The molar ratio of n(o-C6ClH4NO2):n(HSO3Cl) = 1:4; The raw material has been fed in batches and the ration Na2SO4 is added, reaction temperature is 140°C, reaction time is 6-7 b. The product n (2-nitrochlorobenzene-4-sulfochlorides):n(NH3) = 1:1.5 has been treated with ammonia water at reaction temperature 38-40°C for 2 h, and treated with 30% NaOH solution at 105°C for 3-4 h, and then phase transfer catalyst is added, finally after acidifying, the product can be obtained. The excellent yield was 70%. The three products obtained in above three phases were characterized by IR. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).SDS of cas: 97-09-6
The Article related to nitrophenol sulfonylamide preparation, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Dye Intermediates and other aspects.SDS of cas: 97-09-6
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics