On November 8, 2020, Lajin, Bassam; Goessler, Walter published an article.Recommanded Product: 79-07-2 The title of the article was Fluorinated carboxylic acids as “ion repelling agents” in reversed-phase chromatography. And the article contained the following:
Fluorinated carboxylic acids have been in use as ion-pairing reagents for over three decades. It has been observed that ion-pairing reagents not only increase the retention of oppositely charged analytes on reversed-phase HPLC columns but also decrease the retention of similarly charged analytes; these latter effects, however, have not been thoroughly investigated for the fluorinated carboxylic acids, and the application of these reagents has been rather restricted to their ion-pairing capacity to sep. basic analytes. In the present study, we report a systematic investigation about the effects of three fluorinated carboxylic acids (trifluoroacetic acid (TFA), pentafluoropropionic acid (PFPA), and heptafluorobutyric acid (HFBA)) on the retention and selectivity of the separation of halogenated carboxylic acids and sulfonic acids by reversed-phase chromatog. with an inductively coupled plasma mass spectrometry detector (ICPMS). Several eluents were tested and compared at different concentrations (0-100 mM) and pH values, including sulfate, nitrate, phosphate, oxalate, TFA, PFPA, and HFBA. The fluorinated carboxylic acids resulted in a consistent decrease in the retention factors (up to ca. 9-fold with HFBA) in a concentration dependent manner, which plateaued at around 50 mM. Significant improvement of the peak symmetry of the chromatographed acids was also observed We highlight the advantages of incorporating the fluorinated carboxylic acids in modifying the selectivity and retention of organic acids in reversed phase chromatog. in general, and particularly when employing chromatog. detectors with limited compatibility with organic mobile phases such as the ICPMS. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Recommanded Product: 79-07-2
The Article related to fluorinated carboxylic acid ion repelling agent reversed phase chromatog, alkyl sulfonate, fluorinated acetic acids, heptafluorobutyric acid, icpms, ion-pair chromatography and other aspects.Recommanded Product: 79-07-2
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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics