Kakeya, Nobuharu; Yata, Noboru; Kamada, Akira; Aoki, Masaru published an article in 1970, the title of the article was Biological activities of drugs. IX. Structure-activity relation of sulfonamide carbonic anhydrase inhibitors. 4.Application In Synthesis of 3-Nitro-4-chlorobenzenesulfonamide And the article contains the following content:
Hansch-Fujita’s equation has been applied to an anal. of the natriuretic activity of sulfonamide carbonic anhydrase inhibitors using π and πc as hydrophobic parameters, and σ, ΔpKa, Δppm and Δfr as electronic parameters. Sixteen benzenesulfonamide derivatives were satisfactorily applied to the structure-activity anal. of heterocyclic sulfonamides. It was concluded that a strong natriuretic activity was observed for sulfonamides which had an optimal hydrophobicity and low electronegativity at the sulfamoyl group or a strong inhibitory activity against carbonic anhydrase. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Application In Synthesis of 3-Nitro-4-chlorobenzenesulfonamide
The Article related to structure activity sulfonamides antienzymic, activity structure sulfonamides antienzymic, sulfonamides antienzymic structure activity, antienzymic sulfonamides structure activity, carbonic anhydrase inhibitor structure and other aspects.Application In Synthesis of 3-Nitro-4-chlorobenzenesulfonamide
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