Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 456-64-4, name is 1,1,1-Trifluoro-N-phenylmethanesulfonamide, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 1,1,1-Trifluoro-N-phenylmethanesulfonamide
6- (3-METHOXYPHENYL)-2- (2-MORPHOLIN-4-YL-2-OXOETHYL)-3-HYDROPYRIMIDIN-4-ONE 8 (leq) is dissolved in CH2CL2 in a round bottom flask, oven dried and kept under N2. Triethylamine is added (1.4 eq) followed by N-Phenyl trifluoromethanesulfonimide (1.2 eq) and DMAP (10 mol%). The reaction mixture is stirred at room temperature overnight. The solvent is evaporated under reduced pressure and the residue purified by chromatography on silicagel (ethyl acetate/hexanes 1: 5), obtaining the desired 6- (3-METHOXYPHENYL)-2- (2-MORPHOLIN-4-YL-2-OXOETHYL) pyrimidin-4-yl (trifluoromethyl) sulfonate 9.
According to the analysis of related databases, 456-64-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; CHIRON CORPORATION; WO2004/48365; (2004); A1;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics