On May 25, 2022, Qaroush, Abdussalam K.; Alsayyed, Ahed W.; Eftaiha, Ala’a F.; Al-Qaisi, Feda’a M.; Salameh, Bader A. published an article.Recommanded Product: 102-07-8 The title of the article was Green Microwave-Assisted Synthesis of Cyclic/Acyclic Ureas from Propylene Carbonate. And the article contained the following:
Herein, an organocatalyzed synthetic pathway for the preparation of acyclic ureas RHNC(O)NHR (R = Bu, sec-Bu, Ph, cyclohexyl, cyclohexylmethyl, benzyl)/cyclic ureas I (n = 1, 2) from their parent primary aliphatic or aromatic monoamines NH2(CH2)nCH2NH2/diamines RNH2 with propylene carbonate as a carbonylating agent obtaining reasonable to very good yields with high selectivity has been described. This method is considered green as nine out of twelve green chem. principles (GCPs) are fulfilled. Most importantly, the absence of solvent and, energy-efficient pathway, in addition to the ease of synthesis and separation, under fast reaction times down to a few minutes together with the straightforward workup with min. use of organic solvents are described. This method was successful in preparing 1,3-diphenylurea from aniline giving 8% yield in 10 min, which was not previously reported using aromatic amines with carbonate esters. The method is applicable for primary rather than secondary amines, which implies high chemoselectivity of the former for the synthesis of urea compounds The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Recommanded Product: 102-07-8
The Article related to acyclic urea preparation green chem microwave chemoselective, primary amine propylene carbonate carbonylation diazabicycloundecene catalyst, cyclic urea preparation green chem microwave chemoselective, diamine primary propylene carbonate carbonylation diazabicycloundecene catalyst and other aspects.Recommanded Product: 102-07-8
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics