On June 1, 2021, Pereira, Kelly L.; Ward, Martyn W.; Wilkinson, John L.; Sallach, Jonathan Brett; Bryant, Daniel J.; Dixon, William J.; Hamilton, Jacqueline F.; Lewis, Alastair C. published an article.Application In Synthesis of 1,3-Diphenylurea The title of the article was An automated methodology for non-targeted compositional analysis of small molecules in high complexity environmental matrices using coupled ultra performance liquid chromatography orbitrap mass spectrometry. And the article contained the following:
The life-critical matrixes of air and water are among the most complex chem. mixtures that are ever encountered. Ultrahigh-resolution mass spectrometers, such as the Orbitrap, provide unprecedented anal. capabilities to probe the mol. composition of such matrixes, but the extraction of non-targeted chem. information is impractical to perform via manual data processing. Automated non-targeted tools rapidly extract the chem. information of all detected compounds within a sample dataset. However, these methods have not been exploited in the environmental sciences. Here, we provide an automated and (for the first time) rigorously tested methodol. for the non-targeted compositional anal. of environmental matrixes using coupled liquid chromatog.-mass spectrometric data. First, the robustness and reproducibility was tested using authentic standards, evaluating performance as a function of concentration, ionization potential, and sample complexity. The method was then used for the compositional anal. of particulate matter and surface waters collected from worldwide locations. The method detected >9600 compounds in the individual environmental samples, arising from critical pollutant sources, including carcinogenic industrial chems., pesticides, and pharmaceuticals among others. This methodol. offers considerable advances in the environmental sciences, providing a more complete assessment of sample compositions while significantly increasing throughput. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application In Synthesis of 1,3-Diphenylurea
The Article related to automated methodol nontargeted compositional analysis small mol environmental matrixes, coupled ultra performance liquid chromatog orbitrap mass spectrometry, compound discoverer, liquid chromatography−mass spectrometry, non-targeted analysis, ultrahigh-resolution mass spectrometry and other aspects.Application In Synthesis of 1,3-Diphenylurea
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