Liu, Jiaxin; Wei, Yin; Shi, Min published an article in 2021. The article was titled 《Visible light mediated synthesis of 4-aryl-1,2-dihydronaphthalene derivatives via single-electron oxidation or MHAT from methylenecyclopropanes》, and you may find the article in Organic Chemistry Frontiers.Computed Properties of C4H9NO2 The information in the text is summarized as follows:
A direct single-electron oxidation of methylenecyclopropanes (MCPs) I (R = H, 2-Me, 3-OMe, 4-F, etc.; R1 = H, 2-Me, 3-Cl, 4-F, etc.) for the rapid construction of 4-aryl-1,2-dihydronaphthalene derivatives II (R2 = H, 5-Me, 6-OMe, 7-F, etc.; R3 = H, F) and III (R4 = R5 = H, F) by merging visible light photoredox catalysis and cobalt catalysis was reported. In MeCN with Et3N·3HF (1.0 equivalent), the fluorination of MCPs I can be realized in the presence of 9-mesityl-10-methylacridinium perchlorate and Co(dmgH)2PyCl, affording fluorinated 4-aryl-1,2-dihydronaphthalene derivatives II (R3 = F) in moderate yields. In MeCN/HFIP (7 : 3), 4-aryl-1,2-dihydronaphthalene derivatives II (R3 = H) and III were obtained in good yields through a metal-catalyzed hydrogen atom transfer process under similar conditions. In addition to this study using N-Methoxy-N-methylacetamide, there are many other studies that have used N-Methoxy-N-methylacetamide(cas: 78191-00-1Computed Properties of C4H9NO2) was used in this study.
N-Methoxy-N-methylacetamide(cas: 78191-00-1) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Computed Properties of C4H9NO2
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics