In 2013,Urabe, Fumiya; Nagashima, Shunsuke; Takahashi, Keisuke; Ishihara, Jun; Hatakeyama, Susumi published 《Total Synthesis of (-)-Cinatrin C1 Based on an In(OTf)3-Catalyzed Conia-Ene Reaction》.Journal of Organic Chemistry published the findings.Application of 71432-55-8 The information in the text is summarized as follows:
The stereocontrolled total synthesis of (-)-cinatrin C1 (I), a phospholipase A2 inhibitor, has been accomplished. The key feature includes the stereoselective construction of the highly substituted THF core by In(OTf)3-catalyzed Conia-ene reaction of the oxygen-tethered acetylenic malonic ester II followed by dihydroxylation with concomitant lactonization. The experimental part of the paper was very detailed, including the reaction process of tert-Butyl N,N’-diisopropylcarbamimidate(cas: 71432-55-8Application of 71432-55-8)
tert-Butyl N,N’-diisopropylcarbamimidate(cas: 71432-55-8) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Application of 71432-55-8
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics