In 2018,Nowak, Monika; Fornal, Emilia; Kontek, Renata; Sroczynski, Dariusz; Jozwiak, Andrzej; Augustowska, Ewelina; Warpas, Anna; Adamczyk, Marta; Malinowski, Zbigniew published 《Synthesis of acylnaphthylamines and their applications in the formation of benzoquinazolines》.ARKIVOC (Gainesville, FL, United States) published the findings.SDS of cas: 78191-00-1 The information in the text is summarized as follows:
The synthesis of acyl N-Boc-1-naphthylamines I (R1 = Me, t-Bu) and N-Boc-2-naphthylamines II (R2 = Me, i-Pr) and their transformation into alkyl substituted benzoquinazolines III (R3 = Me, t-Bu; X = H, Br) and alkyl substituted benzoquinazolinones IV (R4 = Me, i-Pr), V (R5 = Me, t-Bu) through the reaction with formamide or potassium cyanate in the presence of ammonium acetate is described. Presented acyl derivatives were obtained from the reactions of the corresponding lithiated N-Boc naphthylamines with various acetylating agents like AcCl, Ac2O, AcOEt, PivCl, i-PrCOCl and also Weinreb amides. Biol. screening of the potential cytotoxicity on the HT29 cell line and lymphocytes were demonstrated for some benzoquinazoline derivatives After reading the article, we found that the author used N-Methoxy-N-methylacetamide(cas: 78191-00-1SDS of cas: 78191-00-1)
N-Methoxy-N-methylacetamide(cas: 78191-00-1) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).SDS of cas: 78191-00-1
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics