Zhang, Youcan; Yin, Zhiping; Wu, Xiao-Feng published the artcile< Copper-catalyzed carbonylative synthesis of β-homoprolines from N-fluoro-sulfonamides>, Application In Synthesis of 6961-82-6, the main research area is amino acid homoproline synthesis solvent effect; fluoro sulfonamide carbonylation copper catalyst; carbonylation mechanism intramol cyclization free carbon radical.
A new methodol. for the carbonylative transformation of N-fluoro-sulfonamides into N-sulfonyl-β-homoproline esters has been described. In the presence of a catalytic amount of Cu(OTf)2, a range of β-homoproline derivatives were prepared in moderate to good yield. The reaction proceeds via the intramol. cyclization and intermol. carbonylation of a free carbon radical. Notably, this procedure offers the possibility to build potential functionalized bioactive mols.
Organic Letters published new progress about Amino acids Role: SPN (Synthetic Preparation), PREP (Preparation). 6961-82-6 belongs to class amides-buliding-blocks, and the molecular formula is C6H6ClNO2S, Application In Synthesis of 6961-82-6.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics