《Catalytic, Directed C-C Bond Functionalization of Styrenes》 was published in Journal of the American Chemical Society in 2020. These research results belong to Onodera, Shunsuke; Togashi, Ryo; Ishikawa, Soya; Kochi, Takuya; Kakiuchi, Fumitoshi. Application In Synthesis of N-Methoxy-N-methylacetamide The article mentions the following:
A method for catalytic conversion of C(aryl)-C(alkenyl) bonds in styrene derivatives R1-2-R2C6H3C(=CHR4)R3 (R1 = H, 4-Me, 3-Cl, 5-Me, etc.; R2 = 1-pyrazolyl, 2-pyridyl; R3 = H, Me, Ph, 4-methoxyphenyl, etc.; R4 = H, Ph, 4-chlorophenyl) to new C-C bonds is developed. In the presence of a rhodium catalyst, the alkenyl groups of styrenes bearing a pyrazolyl directing group were efficiently converted to other carbon substituents upon reacting with various alkenes RCH=CH2 (R = 4-methylhex-1-en-1-yl, 2-cyclohexylethenyl, 2-phenylethenyl, etc.) and allyl alcs. R5CH(OH)CH=CH2(R5 = cyclohexyl, Me, Et, etc.). It is also indicated that the C-C bond cleavage proceeded via a hydrometalation/β-carbon elimination pathway. The experimental part of the paper was very detailed, including the reaction process of N-Methoxy-N-methylacetamide(cas: 78191-00-1Application In Synthesis of N-Methoxy-N-methylacetamide)
N-Methoxy-N-methylacetamide(cas: 78191-00-1) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).Application In Synthesis of N-Methoxy-N-methylacetamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics