《Fluorescent Membrane Tension Probes for Super-Resolution Microscopy: Combining Mechanosensitive Cascade Switching with Dynamic-Covalent Ketone Chemistry》 was written by Garcia-Calvo, Jose; Maillard, Jimmy; Fureraj, Ina; Strakova, Karolina; Colom, Adai; Mercier, Vincent; Roux, Aurelien; Vauthey, Eric; Sakai, Naomi; Furstenberg, Alexandre; Matile, Stefan. SDS of cas: 78191-00-1 And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:
The authors report the design, synthesis, and evaluation of fluorescent flipper probes for single-mol. super-resolution imaging of membrane tension in living cells. Reversible switching from bright-state ketones to dark-state hydrates, hemiacetals, and hemithioacetals is demonstrated for twisted and planarized mechanophores in solution and membranes. Broadband femtosecond fluorescence up-conversion spectroscopy evinces ultrafast chalcogen-bonding cascade switching in the excited state in solution According to fluorescence lifetime imaging microscopy, the new flippers image membrane tension in live cells with record red shifts and photostability. Single-mol. localization microscopy with the new tension probes resolves membranes well below the diffraction limit. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methylacetamide(cas: 78191-00-1SDS of cas: 78191-00-1)
N-Methoxy-N-methylacetamide(cas: 78191-00-1) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.SDS of cas: 78191-00-1
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Amide – an overview | ScienceDirect Topics